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Found 84 with Last Name = 'lewander' and Initial = 't'
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50030418(1-((7R,8S)-7-Dipropylamino-8-methyl-5,6,7,8-tetrah...)
Affinity DataKi:  0.560nMAssay Description:Binding affinity for 5-hydroxytryptamine 1A receptor in rat brain tissue using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50030004(1-((S)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthal...)
Affinity DataKi:  0.700nMAssay Description:Inhibition of [3H]- 8-OH-DPAT binding to 5-HT1A-receptor from rat cerebral cortex membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50030004(1-((S)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthal...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50030012(1-(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50016777(((R)-8-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  1.30nMAssay Description:Compound was evaluated for inhibiting the binding of [3H]- 8-OH-DPAT to 5-HT1A-receptor from cerebral cortex membranes of ratMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50016777(((R)-8-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50030026(((R)-8-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of [3H]- 8-OH-DPAT binding to 5-HT1A-receptor from rat cerebral cortex membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50030026(((R)-8-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50030019((S)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalene...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50030019((S)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalene...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of [3H]- 8-OH-DPAT binding to 5-HT1A-receptor from rat cerebral cortex membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50011247(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol...)
Affinity DataKi:  1.80nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50030025(1-((R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthal...)
Affinity DataKi:  1.80nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50011247(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol...)
Affinity DataKi:  1.80nMAssay Description:Compound was evaluated for inhibiting the binding of [3H]- 8-OH-DPAT to 5-HT1A-receptor from cerebral cortex membranes of ratMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50030025(1-((R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthal...)
Affinity DataKi:  1.80nMAssay Description:Inhibition of [3H]- 8-OH-DPAT binding to 5-HT1A-receptor from rat cerebral cortex membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50013016(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1-c...)
Affinity DataKi:  2.40nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50030415(((7R,8S)-7-Dipropylamino-8-methyl-5,6,7,8-tetrahyd...)
Affinity DataKi:  2.60nMAssay Description:Binding affinity for 5-hydroxytryptamine 1A receptor in rat brain tissue using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50030027((7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-y...)
Affinity DataKi:  2.80nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50030010(((S)-8-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  2.80nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50030010(((S)-8-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  2.80nMAssay Description:Inhibition of [3H]- 8-OH-DPAT binding to 5-HT1A-receptor from rat cerebral cortex membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50011261((+)7-Dipropylamino-8-methyl-5,6,7,8-tetrahydro-nap...)
Affinity DataKi:  2.90nMAssay Description:Binding affinity for 5-hydroxytryptamine 1A receptor in rat brain tissue using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50030001(CHEMBL89014 | Trifluoro-methanesulfonic acid (R)-7...)
Affinity DataKi:  3.80nMAssay Description:Inhibition of [3H]- 8-OH-DPAT binding to 5-HT1A-receptor from rat cerebral cortex membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50030001(CHEMBL89014 | Trifluoro-methanesulfonic acid (R)-7...)
Affinity DataKi:  3.80nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50030016((8-Ethynyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dip...)
Affinity DataKi:  4nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50016777(((R)-8-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  4.10nMAssay Description:Binding affinity for 5-hydroxytryptamine 1A receptor in rat brain tissue using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50030002((R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalene...)
Affinity DataKi:  4.30nMAssay Description:Inhibition of [3H]- 8-OH-DPAT binding to 5-HT1A-receptor from rat cerebral cortex membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50030002((R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalene...)
Affinity DataKi:  4.30nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50029999((7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-y...)
Affinity DataKi:  4.60nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50030406(((1S,2R)-8-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...)
Affinity DataKi:  6nMAssay Description:Binding affinity for 5-hydroxytryptamine 1A receptor in rat brain tissue using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50030005(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1-c...)
Affinity DataKi:  6nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50030405(CHEMBL290546 | Trifluoro-methanesulfonic acid (7R,...)
Affinity DataKi:  6.70nMAssay Description:Binding affinity for 5-hydroxytryptamine 1A receptor in rat brain tissue using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50030421(((7S,8R)-7-Dipropylamino-8-methyl-5,6,7,8-tetrahyd...)
Affinity DataKi:  7.60nMAssay Description:Binding affinity for 5-hydroxytryptamine 1A receptor in rat brain tissue using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50030024(((R)-8-Phenyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-...)
Affinity DataKi:  7.70nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50030024(((R)-8-Phenyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-...)
Affinity DataKi:  7.70nMAssay Description:Inhibition of [3H]- 8-OH-DPAT binding to 5-HT1A-receptor from rat cerebral cortex membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50030003(CHEMBL88994 | Trifluoro-methanesulfonic acid (S)-7...)
Affinity DataKi:  9.5nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50030003(CHEMBL88994 | Trifluoro-methanesulfonic acid (S)-7...)
Affinity DataKi:  9.5nMAssay Description:Inhibition of [3H]- 8-OH-DPAT binding to 5-HT1A-receptor from rat cerebral cortex membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50029998((8-Phenyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipr...)
Affinity DataKi:  12nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50030020((7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-y...)
Affinity DataKi:  16nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50029997((8-Ethynyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dip...)
Affinity DataKi:  16nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50030009(CHEMBL88157 | Dipropyl-(1,2,3,4-tetrahydro-naphtha...)
Affinity DataKi:  17nMAssay Description:Inhibition of [3H]- 8-OH-DPAT binding to 5-HT1A-receptor from rat cerebral cortex membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50030009(CHEMBL88157 | Dipropyl-(1,2,3,4-tetrahydro-naphtha...)
Affinity DataKi:  17nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50030412((7R,8S)-7-Dipropylamino-8-methyl-5,6,7,8-tetrahydr...)
Affinity DataKi:  18nMAssay Description:Binding affinity for 5-hydroxytryptamine 1A receptor in rat brain tissue using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50030006(1-(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1...)
Affinity DataKi:  19nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50030013(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1-c...)
Affinity DataKi:  19nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50030017((8-Ethynyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dip...)
Affinity DataKi:  22nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50030028((7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-y...)
Affinity DataKi:  23nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50030000(((S)-8-Phenyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-...)
Affinity DataKi:  24nMAssay Description:Inhibition of [3H]- 8-OH-DPAT binding to 5-HT1A-receptor from rat cerebral cortex membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50030000(((S)-8-Phenyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-...)
Affinity DataKi:  24nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50030022((7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-y...)
Affinity DataKi:  25nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50030007(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1-c...)
Affinity DataKi:  26nMAssay Description:Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50011261((+)7-Dipropylamino-8-methyl-5,6,7,8-tetrahydro-nap...)
Affinity DataKi:  30nMAssay Description:In vitro binding affinity towards human Dopamine receptor D2A was determined in mouse fibroblast LtK cells using [3H]-racloprideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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