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Found 90 with Last Name = 'lipinski' and Initial = 'ca'
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006490((+)-(7-Chloro-6-fluoro-4-hydroxy-2-methyl-chroman-...)
Affinity DataIC50:  12nMAssay Description:Compound was tested in vitro for its inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50279984(8-Chloro-1,2,3,4-tetrahydro-acridin-9-ylamine | 9-...)
Affinity DataIC50:  39nMAssay Description:In vitro inhibition of acetylcholinesterase isolated from human erythrocytes.More data for this Ligand-Target Pair
In DepthDetails Article
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50279990(10-Amino-3,4-dihydro-2H-1-oxa-7-aza-9-azonia-anthr...)
Affinity DataIC50:  42nMAssay Description:In vitro inhibition of acetylcholinesterase isolated from human erythrocytes.More data for this Ligand-Target Pair
In DepthDetails Article
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006490((+)-(7-Chloro-6-fluoro-4-hydroxy-2-methyl-chroman-...)
Affinity DataIC50:  46nMAssay Description:Compound was tested in vitro for its inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006490((+)-(7-Chloro-6-fluoro-4-hydroxy-2-methyl-chroman-...)
Affinity DataIC50:  49nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006496((7-Bromo-6-chloro-4-hydroxy-2-methyl-chroman-4-yl)...)
Affinity DataIC50:  50nMAssay Description:Compound was tested in vitro for its inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006500((7-Benzyloxy-6-chloro-4-hydroxy-2-methyl-chroman-4...)
Affinity DataIC50:  60nMAssay Description:Inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006490((+)-(7-Chloro-6-fluoro-4-hydroxy-2-methyl-chroman-...)
Affinity DataIC50:  60nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006530((7-Fluoro-4-hydroxy-2-methyl-6-nitro-chroman-4-yl)...)
Affinity DataIC50:  70nMAssay Description:Inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006496((7-Bromo-6-chloro-4-hydroxy-2-methyl-chroman-4-yl)...)
Affinity DataIC50:  70nMAssay Description:Inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006493(4-Carboxymethyl-4-hydroxy-2-methyl-chroman-7-carbo...)
Affinity DataIC50:  70nMAssay Description:Inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50279995(8-Fluoro-1,2,3,4-tetrahydro-acridin-9-ylamine | 9-...)
Affinity DataIC50:  78nMAssay Description:In vitro inhibition of acetylcholinesterase isolated from human erythrocytes.More data for this Ligand-Target Pair
In DepthDetails Article
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006532((4-Hydroxy-2-methyl-6-nitro-chroman-4-yl)-acetic a...)
Affinity DataIC50:  80nMAssay Description:Inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006507((7-Bromo-6-fluoro-4-hydroxy-2-methyl-chroman-4-yl)...)
Affinity DataIC50:  90nMAssay Description:Inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006533((4-Hydroxy-2,7-dimethyl-6-nitro-chroman-4-yl)-acet...)
Affinity DataIC50:  90nMAssay Description:Inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50279983(8-Methyl-1,2,3,4-tetrahydro-acridin-9-ylamine | CH...)
Affinity DataIC50:  99nMAssay Description:In vitro inhibition of acetylcholinesterase isolated from human erythrocytes.More data for this Ligand-Target Pair
In DepthDetails Article
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006529((6-Chloro-7-ethyl-4-hydroxy-2-methyl-chroman-4-yl)...)
Affinity DataIC50:  100nMAssay Description:Inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006504((7-Chloro-4-hydroxy-2-methyl-6-nitro-chroman-4-yl)...)
Affinity DataIC50:  110nMAssay Description:Inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006507((7-Bromo-6-fluoro-4-hydroxy-2-methyl-chroman-4-yl)...)
Affinity DataIC50:  120nMAssay Description:Compound was tested in vitro for its inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006509((6-Cyano-7-fluoro-4-hydroxy-2-methyl-chroman-4-yl)...)
Affinity DataIC50:  130nMAssay Description:Inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006502((+)-(6,7-Dichloro-4-hydroxy-2-methyl-chroman-4-yl)...)
Affinity DataIC50:  140nMAssay Description:Compound was tested in vitro for its inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  143nMAssay Description:In vitro inhibition of acetylcholinesterase isolated from human erythrocytes.More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50279993(5-Methyl-3,4-dihydro-2H-1-oxa-9-aza-anthracen-10-y...)
Affinity DataIC50:  150nMAssay Description:In vitro inhibition of acetylcholinesterase isolated from human erythrocytes.More data for this Ligand-Target Pair
In DepthDetails Article
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006502((+)-(6,7-Dichloro-4-hydroxy-2-methyl-chroman-4-yl)...)
Affinity DataIC50:  156nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006502((+)-(6,7-Dichloro-4-hydroxy-2-methyl-chroman-4-yl)...)
Affinity DataIC50:  180nMAssay Description:Inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006502((+)-(6,7-Dichloro-4-hydroxy-2-methyl-chroman-4-yl)...)
Affinity DataIC50:  180nMAssay Description:ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006513((6-Chloro-4-hydroxy-7-methoxy-2-methyl-chroman-4-y...)
Affinity DataIC50:  190nMAssay Description:Inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006506((6-Fluoro-4-hydroxy-2-methyl-chroman-4-yl)-acetic ...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006524((6-Chloro-4-hydroxy-2,7-dimethyl-chroman-4-yl)-ace...)
Affinity DataIC50:  240nMAssay Description:Inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006498((6,7-Difluoro-4-hydroxy-2-methyl-chroman-4-yl)-ace...)
Affinity DataIC50:  250nMAssay Description:Inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50279988(10-Amino-3,4-dihydro-2H-1-oxa-9-azonia-anthracene ...)
Affinity DataIC50:  266nMAssay Description:In vitro inhibition of acetylcholinesterase isolated from human erythrocytes.More data for this Ligand-Target Pair
In DepthDetails Article
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006506((6-Fluoro-4-hydroxy-2-methyl-chroman-4-yl)-acetic ...)
Affinity DataIC50:  310nMAssay Description:Compound was tested in vitro for its inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50279981(5-Chloro-3,4-dihydro-2H-1-oxa-9-aza-anthracen-10-y...)
Affinity DataIC50:  313nMAssay Description:In vitro inhibition of acetylcholinesterase isolated from human erythrocytes.More data for this Ligand-Target Pair
In DepthDetails Article
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50279982(5-Fluoro-3,4-dihydro-2H-1-oxa-9-aza-anthracen-10-y...)
Affinity DataIC50:  335nMAssay Description:In vitro inhibition of acetylcholinesterase isolated from human erythrocytes.More data for this Ligand-Target Pair
In DepthDetails Article
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006498((6,7-Difluoro-4-hydroxy-2-methyl-chroman-4-yl)-ace...)
Affinity DataIC50:  350nMAssay Description:Compound was tested in vitro for its inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50279996(1,2,3,4,5,6,7,8-Octahydro-acridin-9-ylamine | CHEM...)
Affinity DataIC50:  360nMAssay Description:In vitro inhibition of acetylcholinesterase isolated from human erythrocytes.More data for this Ligand-Target Pair
In DepthDetails Article
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006508((2-tert-Butyl-6-fluoro-4-hydroxy-chroman-4-yl)-ace...)
Affinity DataIC50:  360nMAssay Description:Inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006519((6-Chloro-7-fluoro-4-hydroxy-2-methyl-chroman-4-yl...)
Affinity DataIC50:  390nMAssay Description:Inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006534((4-Hydroxy-2,2-dimethyl-6-nitro-chroman-4-yl)-acet...)
Affinity DataIC50:  400nMAssay Description:Inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006535((6-Chloro-4-hydroxy-2-methyl-3,4-dihydro-2H-benzo[...)
Affinity DataIC50:  400nMAssay Description:Inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006519((6-Chloro-7-fluoro-4-hydroxy-2-methyl-chroman-4-yl...)
Affinity DataIC50:  410nMAssay Description:Compound was tested in vitro for its inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50279997(6,7,8,9-Tetrahydro-benzo[b][1,8]naphthyridin-5-yla...)
Affinity DataIC50:  429nMAssay Description:In vitro inhibition of acetylcholinesterase isolated from human erythrocytes.More data for this Ligand-Target Pair
In DepthDetails Article
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50279980(3,4,5,6,7,8-Hexahydro-2H-1-oxa-9-aza-anthracen-10-...)
Affinity DataIC50:  455nMAssay Description:In vitro inhibition of acetylcholinesterase isolated from human erythrocytes.More data for this Ligand-Target Pair
In DepthDetails Article
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006503((6-Fluoro-4-hydroxy-2-isopropyl-chroman-4-yl)-acet...)
Affinity DataIC50:  570nMAssay Description:Inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006523((6-Fluoro-4-hydroxy-chroman-4-yl)-acetic acid | CH...)
Affinity DataIC50:  600nMAssay Description:Inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50279994(5-Methoxy-3,4-dihydro-2H-1-oxa-9-aza-anthracen-10-...)
Affinity DataIC50:  606nMAssay Description:In vitro inhibition of acetylcholinesterase isolated from human erythrocytes.More data for this Ligand-Target Pair
In DepthDetails Article
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50279985(8-Methoxy-1,2,3,4-tetrahydro-acridin-9-ylamine | 9...)
Affinity DataIC50:  615nMAssay Description:In vitro inhibition of acetylcholinesterase isolated from human erythrocytes.More data for this Ligand-Target Pair
In DepthDetails Article
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006488((2-Ethyl-6-fluoro-4-hydroxy-chroman-4-yl)-acetic a...)
Affinity DataIC50:  620nMAssay Description:Inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006536((6-Acetyl-4-hydroxy-2-methyl-chroman-4-yl)-acetic ...)
Affinity DataIC50:  650nMAssay Description:Inhibitory activity against human placental aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50279987(2,3,5,6,7,8-Hexahydro-1H-cyclopenta[b]quinolin-9-y...)
Affinity DataIC50:  658nMAssay Description:In vitro inhibition of acetylcholinesterase isolated from human erythrocytes.More data for this Ligand-Target Pair
In DepthDetails Article
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