Compile Data Set for Download or QSAR
maximum 50k data
Found 23 with Last Name = 'lokwani' and Initial = 'dk'
TargetAurora kinase A(Homo sapiens (Human))
Durgamata Institute Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50004205(MK-045 | MK-0457 | TOZASERTIB | US9249124, VX680 |...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of Aurora A (unknown origin) using kemptide acetate as substrate measured after 30 mins by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAurora kinase B(Homo sapiens (Human))
Durgamata Institute Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50600442(CHEMBL5200042)
Affinity DataIC50:  12nMAssay Description:Inhibition of Aurora B (unknown origin) using kemptide acetate as substrate measured after 30 mins by kinase-glo luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAurora kinase A(Homo sapiens (Human))
Durgamata Institute Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50600442(CHEMBL5200042)
Affinity DataIC50:  15nMAssay Description:Inhibition of Aurora A (unknown origin) using kemptide acetate as substrate measured after 30 mins by kinase-glo luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAurora kinase B(Homo sapiens (Human))
Durgamata Institute Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50600441(CHEMBL5180210)
Affinity DataIC50:  15nMAssay Description:Inhibition of Aurora B (unknown origin) using kemptide acetate as substrate measured after 30 mins by kinase-glo luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAurora kinase B(Homo sapiens (Human))
Durgamata Institute Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50004205(MK-045 | MK-0457 | TOZASERTIB | US9249124, VX680 |...)
Affinity DataIC50:  19nMAssay Description:Inhibition of Aurora B (unknown origin) using kemptide acetate as substrate measured after 30 mins by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAurora kinase B(Homo sapiens (Human))
Durgamata Institute Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50600443(CHEMBL5173220)
Affinity DataIC50:  22nMAssay Description:Inhibition of Aurora B (unknown origin) using kemptide acetate as substrate measured after 30 mins by kinase-glo luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAurora kinase A(Homo sapiens (Human))
Durgamata Institute Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50600441(CHEMBL5180210)
Affinity DataIC50:  33nMAssay Description:Inhibition of Aurora A (unknown origin) using kemptide acetate as substrate measured after 30 mins by kinase-glo luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAurora kinase A(Homo sapiens (Human))
Durgamata Institute Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50600443(CHEMBL5173220)
Affinity DataIC50:  42nMAssay Description:Inhibition of Aurora A (unknown origin) using kemptide acetate as substrate measured after 30 mins by kinase-glo luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies

Curated by ChEMBL
LigandPNGBDBM22984((8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-me...)
Affinity DataIC50:  940nMAssay Description:Inhibition of human DNA topoisomerase 2 catalytic activity using supercoiled pRYG DNA as substrate measured after 45 mins in presence of ATP by agaro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies

Curated by ChEMBL
LigandPNGBDBM50543963(CHEMBL4636680)
Affinity DataIC50:  980nMAssay Description:Inhibition of human DNA topoisomerase 2 catalytic activity using supercoiled pRYG DNA as substrate measured after 45 mins in presence of ATP by agaro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies

Curated by ChEMBL
LigandPNGBDBM22984((8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-me...)
Affinity DataIC50:  990nMAssay Description:Inhibition of human topoisomerase-2 alpha in human A498 cells assessed as decrease in relaxation of supercoiled DNA at 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies

Curated by ChEMBL
LigandPNGBDBM50543962(CHEMBL4642846)
Affinity DataIC50:  1.77E+3nMAssay Description:Inhibition of human DNA topoisomerase 2 catalytic activity using supercoiled pRYG DNA as substrate measured after 45 mins in presence of ATP by agaro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies

Curated by ChEMBL
LigandPNGBDBM50543960(CHEMBL4633308)
Affinity DataIC50:  8.15E+3nMAssay Description:Inhibition of human DNA topoisomerase 2 catalytic activity using supercoiled pRYG DNA as substrate measured after 45 mins in presence of ATP by agaro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies

Curated by ChEMBL
LigandPNGBDBM50570427(CHEMBL4864715)
Affinity DataIC50:  1.03E+4nMAssay Description:Inhibition of human topoisomerase-2 alpha in human A498 cells assessed as decrease in relaxation of supercoiled DNA at 10 uMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies

Curated by ChEMBL
LigandPNGBDBM50543961(CHEMBL4647427)
Affinity DataIC50:  1.21E+4nMAssay Description:Inhibition of human DNA topoisomerase 2 catalytic activity using supercoiled pRYG DNA as substrate measured after 45 mins in presence of ATP by agaro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies

Curated by ChEMBL
LigandPNGBDBM50570429(CHEMBL4878037)
Affinity DataIC50:  1.24E+4nMAssay Description:Inhibition of human topoisomerase-2 alpha in human A498 cells assessed as decrease in relaxation of supercoiled DNA at 10 uMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies

Curated by ChEMBL
LigandPNGBDBM50543958(CHEMBL4643603)
Affinity DataIC50:  1.55E+4nMAssay Description:Inhibition of human DNA topoisomerase 2 catalytic activity using supercoiled pRYG DNA as substrate measured after 45 mins in presence of ATP by agaro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies

Curated by ChEMBL
LigandPNGBDBM50570428(CHEMBL4870551)
Affinity DataIC50:  1.67E+4nMAssay Description:Inhibition of human topoisomerase-2 alpha in human A498 cells assessed as decrease in relaxation of supercoiled DNA at 10 uMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies

Curated by ChEMBL
LigandPNGBDBM50570432(CHEMBL4849502)
Affinity DataIC50:  1.71E+4nMAssay Description:Inhibition of human topoisomerase-2 alpha in human A498 cells assessed as decrease in relaxation of supercoiled DNA at 10 uMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies

Curated by ChEMBL
LigandPNGBDBM50543959(CHEMBL4636706)
Affinity DataIC50:  2.08E+4nMAssay Description:Inhibition of human DNA topoisomerase 2 catalytic activity using supercoiled pRYG DNA as substrate measured after 45 mins in presence of ATP by agaro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies

Curated by ChEMBL
LigandPNGBDBM50570430(CHEMBL4855587)
Affinity DataIC50:  2.64E+4nMAssay Description:Inhibition of human topoisomerase-2 alpha in human A498 cells assessed as decrease in relaxation of supercoiled DNA at 10 uMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies

Curated by ChEMBL
LigandPNGBDBM50570431(CHEMBL4869150)
Affinity DataIC50:  3.99E+4nMAssay Description:Inhibition of human topoisomerase-2 alpha in human A498 cells assessed as decrease in relaxation of supercoiled DNA at 10 uMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies

Curated by ChEMBL
LigandPNGBDBM50570433(CHEMBL4853443)
Affinity DataIC50:  4.84E+4nMAssay Description:Inhibition of human topoisomerase-2 alpha in human A498 cells assessed as decrease in relaxation of supercoiled DNA at 10 uMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed