Affinity DataIC50: 1.90nMAssay Description:Inhibition of Aurora A (unknown origin) using kemptide acetate as substrate measured after 30 mins by kinase-glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of Aurora B (unknown origin) using kemptide acetate as substrate measured after 30 mins by kinase-glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of Aurora A (unknown origin) using kemptide acetate as substrate measured after 30 mins by kinase-glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of Aurora B (unknown origin) using kemptide acetate as substrate measured after 30 mins by kinase-glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of Aurora B (unknown origin) using kemptide acetate as substrate measured after 30 mins by kinase-glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of Aurora B (unknown origin) using kemptide acetate as substrate measured after 30 mins by kinase-glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of Aurora A (unknown origin) using kemptide acetate as substrate measured after 30 mins by kinase-glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of Aurora A (unknown origin) using kemptide acetate as substrate measured after 30 mins by kinase-glo luminescence assayMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies
Curated by ChEMBL
Prof John Barnabas Post Graduate School of Biological Studies
Curated by ChEMBL
Affinity DataIC50: 940nMAssay Description:Inhibition of human DNA topoisomerase 2 catalytic activity using supercoiled pRYG DNA as substrate measured after 45 mins in presence of ATP by agaro...More data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies
Curated by ChEMBL
Prof John Barnabas Post Graduate School of Biological Studies
Curated by ChEMBL
Affinity DataIC50: 980nMAssay Description:Inhibition of human DNA topoisomerase 2 catalytic activity using supercoiled pRYG DNA as substrate measured after 45 mins in presence of ATP by agaro...More data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies
Curated by ChEMBL
Prof John Barnabas Post Graduate School of Biological Studies
Curated by ChEMBL
Affinity DataIC50: 990nMAssay Description:Inhibition of human topoisomerase-2 alpha in human A498 cells assessed as decrease in relaxation of supercoiled DNA at 10 uMMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies
Curated by ChEMBL
Prof John Barnabas Post Graduate School of Biological Studies
Curated by ChEMBL
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of human DNA topoisomerase 2 catalytic activity using supercoiled pRYG DNA as substrate measured after 45 mins in presence of ATP by agaro...More data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies
Curated by ChEMBL
Prof John Barnabas Post Graduate School of Biological Studies
Curated by ChEMBL
Affinity DataIC50: 8.15E+3nMAssay Description:Inhibition of human DNA topoisomerase 2 catalytic activity using supercoiled pRYG DNA as substrate measured after 45 mins in presence of ATP by agaro...More data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies
Curated by ChEMBL
Prof John Barnabas Post Graduate School of Biological Studies
Curated by ChEMBL
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of human topoisomerase-2 alpha in human A498 cells assessed as decrease in relaxation of supercoiled DNA at 10 uMMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies
Curated by ChEMBL
Prof John Barnabas Post Graduate School of Biological Studies
Curated by ChEMBL
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of human DNA topoisomerase 2 catalytic activity using supercoiled pRYG DNA as substrate measured after 45 mins in presence of ATP by agaro...More data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies
Curated by ChEMBL
Prof John Barnabas Post Graduate School of Biological Studies
Curated by ChEMBL
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of human topoisomerase-2 alpha in human A498 cells assessed as decrease in relaxation of supercoiled DNA at 10 uMMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies
Curated by ChEMBL
Prof John Barnabas Post Graduate School of Biological Studies
Curated by ChEMBL
Affinity DataIC50: 1.55E+4nMAssay Description:Inhibition of human DNA topoisomerase 2 catalytic activity using supercoiled pRYG DNA as substrate measured after 45 mins in presence of ATP by agaro...More data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies
Curated by ChEMBL
Prof John Barnabas Post Graduate School of Biological Studies
Curated by ChEMBL
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibition of human topoisomerase-2 alpha in human A498 cells assessed as decrease in relaxation of supercoiled DNA at 10 uMMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies
Curated by ChEMBL
Prof John Barnabas Post Graduate School of Biological Studies
Curated by ChEMBL
Affinity DataIC50: 1.71E+4nMAssay Description:Inhibition of human topoisomerase-2 alpha in human A498 cells assessed as decrease in relaxation of supercoiled DNA at 10 uMMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies
Curated by ChEMBL
Prof John Barnabas Post Graduate School of Biological Studies
Curated by ChEMBL
Affinity DataIC50: 2.08E+4nMAssay Description:Inhibition of human DNA topoisomerase 2 catalytic activity using supercoiled pRYG DNA as substrate measured after 45 mins in presence of ATP by agaro...More data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies
Curated by ChEMBL
Prof John Barnabas Post Graduate School of Biological Studies
Curated by ChEMBL
Affinity DataIC50: 2.64E+4nMAssay Description:Inhibition of human topoisomerase-2 alpha in human A498 cells assessed as decrease in relaxation of supercoiled DNA at 10 uMMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies
Curated by ChEMBL
Prof John Barnabas Post Graduate School of Biological Studies
Curated by ChEMBL
Affinity DataIC50: 3.99E+4nMAssay Description:Inhibition of human topoisomerase-2 alpha in human A498 cells assessed as decrease in relaxation of supercoiled DNA at 10 uMMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Prof John Barnabas Post Graduate School of Biological Studies
Curated by ChEMBL
Prof John Barnabas Post Graduate School of Biological Studies
Curated by ChEMBL
Affinity DataIC50: 4.84E+4nMAssay Description:Inhibition of human topoisomerase-2 alpha in human A498 cells assessed as decrease in relaxation of supercoiled DNA at 10 uMMore data for this Ligand-Target Pair