Affinity DataKi: 5.70nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor in rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Displacement of [3H]PT-1284 human muscarinic acetylcholine receptor M1 expressed in CHO cell membranes after 90 mins scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Displacement of [3H]PT-1284 human muscarinic acetylcholine receptor M1 expressed in CHO cell membranes after 90 mins scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Displacement of [3H]PT-1284 human muscarinic acetylcholine receptor M1 expressed in CHO cell membranes after 90 mins scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor in rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:In vitro inhibitory activity against [3H]- (+)-3-PPP binding to Sigma opioid receptor in guinea pig brain membrane homogenatesMore data for this Ligand-Target Pair
Affinity DataKi: 72nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor in rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Activity at rat mGlu5 receptor expressed in CHO cells assessed as inhibition of quisqualate-stimulated calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Activity at rat mGlu5 receptor expressed in CHO cells assessed as inhibition of quisqualate-stimulated calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Activity at rat mGlu5 receptor expressed in CHO cells assessed as inhibition of quisqualate-stimulated calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Activity at rat mGlu5 receptor expressed in CHO cells assessed as inhibition of quisqualate-stimulated calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Activity at rat mGlu5 receptor expressed in CHO cells assessed as inhibition of quisqualate-stimulated calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Activity at rat mGlu5 receptor expressed in CHO cells assessed as inhibition of quisqualate-stimulated calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Activity at rat mGlu5 receptor expressed in CHO cells assessed as inhibition of quisqualate-stimulated calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.70nMAssay Description:Activity at rat mGlu5 receptor expressed in CHO cells assessed as inhibition of quisqualate-stimulated calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Activity at rat mGlu5 receptor expressed in CHO cells assessed as inhibition of quisqualate-stimulated calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Activity at rat mGlu5 receptor expressed in CHO cells assessed as inhibition of quisqualate-stimulated calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Activity at rat mGlu5 receptor expressed in CHO cells assessed as inhibition of quisqualate-stimulated calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of N-type calcium channels in IMR-32 human neuroblastoma cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Displacement of [3H]gabapentin from alpha-2delta calcium channel in pig brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 72nMAssay Description:Activity at rat mGlu5 receptor expressed in CHO cells assessed as inhibition of quisqualate-stimulated calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 75nMAssay Description:Activity at rat mGlu5 receptor expressed in CHO cells assessed as inhibition of quisqualate-stimulated calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 82nMAssay Description:Activity at rat mGlu5 receptor expressed in CHO cells assessed as inhibition of quisqualate-stimulated calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]gabapentin from alpha-2delta calcium channel in pig brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 108nMAssay Description:Displacement of [3H]gabapentin from alpha-2delta calcium channel in pig brain membraneMore data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of N-type calcium channels in IMR-32 human neuroblastoma cellsMore data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of N-type Voltage Sensitive Calcium Channel (VSCC) using IMR-32 assayMore data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of N-type Voltage Sensitive Calcium Channel (VSCC) using IMR-32 assayMore data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:In vitro inhibitory activity against N-type calcium channel in the IMR-32 human neuroblastoma cellsMore data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of N-type calcium channels in IMR-32 human neuroblastoma cellsMore data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of N-type calcium channels in IMR32 human neuroblastoma cellsMore data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:In vitro inhibitory activity against N-type calcium channel in the IMR-32 human neuroblastoma cellsMore data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of N-type calcium channels in IMR-32 human neuroblastoma cellsMore data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of N-type Voltage Sensitive Calcium Channel (VSCC) using IMR-32 assayMore data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Activity at rat mGlu5 receptor expressed in CHO cells assessed as inhibition of quisqualate-stimulated calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:In vitro inhibitory activity against N-type calcium channel in the IMR-32 human neuroblastoma cellsMore data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Inhibition of N-type calcium channels in IMR32 human neuroblastoma cellsMore data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:In vitro inhibitory activity against N-type calcium channel in the IMR-32 human neuroblastoma cellsMore data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 340nMAssay Description:Inhibition of N-type calcium channels in IMR32 human neuroblastoma cellsMore data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 340nMAssay Description:Inhibition of N-type Voltage Sensitive Calcium Channel (VSCC) using IMR-32 assayMore data for this Ligand-Target Pair
Affinity DataIC50: 360nMAssay Description:Activity at rat mGlu5 receptor expressed in CHO cells assessed as inhibition of quisqualate-stimulated calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 360nMAssay Description:Inhibition of N-type calcium channels in IMR-32 human neuroblastoma cellsMore data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 380nMAssay Description:In vitro inhibitory activity against N-type calcium channel in the IMR-32 human neuroblastoma cellsMore data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:In vitro inhibitory activity against N-type calcium channel in the IMR-32 human neuroblastoma cellsMore data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of N-type Voltage Sensitive Calcium Channel (VSCC) using IMR-32 assayMore data for this Ligand-Target Pair
Affinity DataIC50: 430nMAssay Description:Activity at rat mGlu5 receptor expressed in CHO cells assessed as inhibition of quisqualate-stimulated calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 430nMAssay Description:Inhibition of N-type calcium channels in IMR32 human neuroblastoma cellsMore data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 480nMAssay Description:Inhibition of N-type calcium channels in IMR32 human neuroblastoma cellsMore data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 490nMAssay Description:Inhibition of N-type Voltage Sensitive Calcium Channel (VSCC) using IMR-32 assayMore data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of N-type calcium channels in IMR-32 human neuroblastoma cellsMore data for this Ligand-Target Pair