Compile Data Set for Download or QSAR
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Found 1902 with Last Name = 'lotti' and Initial = 'vj'
TargetCholecystokinin(GUINEA PIG)
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM81963(CAS_9011-97-6 | CCK | CCK33 | CHOLECYSTOKININ)
Affinity DataKi:  0.0500nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin(GUINEA PIG)
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM50005463((R)-1H-Indole-2-carboxylic acid (1-methyl-2-oxo-5-...)
Affinity DataKi:  0.0800nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50021195(2-Hydroxy-ethanesulfonic acid (1,3,4,5,6,11b-hexah...)
Affinity DataKi:  0.770nMAssay Description:Evaluated for its ability to displace [3H]-clonidine from alpha-2 adrenergic receptor of calf cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin(GUINEA PIG)
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM81963(CAS_9011-97-6 | CCK | CCK33 | CHOLECYSTOKININ)
Affinity DataKi:  0.900nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM31046(3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphe...)
Affinity DataKi:  0.930nMAssay Description:Binding affinity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]prazosin as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin(GUINEA PIG)
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM50061220(1-((S)-1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benz...)
Affinity DataKi:  1.10nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50021195(2-Hydroxy-ethanesulfonic acid (1,3,4,5,6,11b-hexah...)
Affinity DataKi:  1.10nMAssay Description:Compound was tested for inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50021196(2-Hydroxy-ethanesulfonic acid (1,3,4,5,6,11b-hexah...)
Affinity DataKi:  1.40nMAssay Description:Evaluated for its ability to displace [3H]-clonidine from alpha-2 adrenergic receptor of calf cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50019848(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1...)
Affinity DataKi:  1.5nMAssay Description:Binding activity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]-clonidine as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50021196(2-Hydroxy-ethanesulfonic acid (1,3,4,5,6,11b-hexah...)
Affinity DataKi:  1.60nMAssay Description:Compound was tested for inhibition of hog kidney reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50027034((4,5-Dihydro-1H-imidazol-2-ylmethyl)-phenyl-p-toly...)
Affinity DataKi:  1.80nMAssay Description:Binding affinity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]clonidine as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50027031((2-Chloro-phenyl)-(4,5-dihydro-1H-imidazol-2-ylmet...)
Affinity DataKi:  1.80nMAssay Description:Binding affinity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]clonidine as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(MOUSE)
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM50061220(1-((S)-1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benz...)
In DepthDetails ArticlePubMed
TargetCholecystokinin(GUINEA PIG)
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM50061220(1-((S)-1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benz...)
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM31046(3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphe...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]prazosin as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin(GUINEA PIG)
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM50061220(1-((S)-1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benz...)
Affinity DataKi:  2.20nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM50061220(1-((S)-1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benz...)
Affinity DataKi:  2.40nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50027014(1-(3-Chloro-pyridin-2-yl)-4-methyl-piperazine | CH...)
Affinity DataKi:  2.70nMAssay Description:Binding activity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]-clonidine as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50027027(1-(3-Bromo-pyridin-2-yl)-4-methyl-piperazine | CHE...)
Affinity DataKi:  2.90nMAssay Description:Binding activity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]-clonidine as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin(GUINEA PIG)
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM81964(CAS_5486814 | Gastrin | NSC_5486814 | Neuromedin C)
In DepthDetails ArticlePubMed
TargetCholecystokinin(GUINEA PIG)
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM81962(S-L-365,260)
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50027036((4,5-Dihydro-1H-imidazol-2-ylmethyl)-methyl-p-toly...)
Affinity DataKi:  3.30nMAssay Description:Binding affinity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]clonidine as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM50061220(1-((S)-1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benz...)
Affinity DataKi:  3.90nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin(GUINEA PIG)
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM81964(CAS_5486814 | Gastrin | NSC_5486814 | Neuromedin C)
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50026633(1-(3-Fluoro-pyridin-2-yl)-4-methyl-piperazine | CH...)
Affinity DataKi:  5nMAssay Description:Binding activity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]-clonidine as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50027034((4,5-Dihydro-1H-imidazol-2-ylmethyl)-phenyl-p-toly...)
Affinity DataKi:  5.60nMAssay Description:Binding affinity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]prazosin as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50027035(3-[(4,5-Dihydro-1H-imidazol-2-ylmethyl)-amino]-phe...)
Affinity DataKi:  7.10nMAssay Description:Binding affinity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]clonidine as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50027019(1-(3-Chloro-pyridin-2-yl)-piperazine | CHEMBL29800...)
Affinity DataKi:  7.90nMAssay Description:Binding activity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]-clonidine as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50027024(1-(3-Fluoro-pyridin-2-yl)-piperazine | CHEMBL48833...)
Affinity DataKi:  8.20nMAssay Description:Binding activity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]-clonidine as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50013515((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)
Affinity DataKi:  10nMAssay Description:Compound was tested for inhibition of hog kidney reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50027013(1-(3-Bromo-pyridin-2-yl)-piperazine | CHEMBL295921)
Affinity DataKi:  11nMAssay Description:Binding activity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]-clonidine as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50027032((4,5-Dihydro-1H-imidazol-2-ylmethyl)-p-tolyl-amine...)
Affinity DataKi:  14nMAssay Description:Binding affinity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]clonidine as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50027037((4,5-Dihydro-1H-imidazol-2-ylmethyl)-ethyl-p-tolyl...)
Affinity DataKi:  14nMAssay Description:Binding affinity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]clonidine as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50027015(2-Piperazin-1-yl-nicotinonitrile | CHEMBL48137)
Affinity DataKi:  14nMAssay Description:Binding activity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]-clonidine as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM31005(2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyraz...)
Affinity DataKi:  17nMAssay Description:Binding activity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]-clonidine as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50027021(1-(6-Chloro-pyridin-2-yl)-piperazine | CHEMBL45773)
Affinity DataKi:  18nMAssay Description:Binding activity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]-clonidine as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50026636(17alpha-hydroxy-20alpha-yohimban-16beta-carboxylic...)
Affinity DataKi:  18nMAssay Description:Binding activity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]-clonidine as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin(GUINEA PIG)
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM50005459(4-(3,4-Dichloro-benzoylamino)-4-dipentylcarbamoyl-...)
Affinity DataKi:  22nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Dog)
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM50061220(1-((S)-1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benz...)
Affinity DataKi:  23nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50001901(1-(2-Chloro-phenyl)-piperazine | CHEMBL9841)
Affinity DataKi:  25nMAssay Description:Binding activity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]-clonidine as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50027020(1-(3-Nitro-pyridin-2-yl)-piperazine | CHEMBL296653)
Affinity DataKi:  26nMAssay Description:Binding activity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]-clonidine as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(RABBIT)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035429(4'-[2-Butyl-6-(3-cyclohexyl-ureido)-benzoimidazol-...)
Affinity DataKi:  29nMAssay Description:Tested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50026634(1-(2-pyridyl)piperazine | 1-(pyridin-2-yl)piperazi...)
Affinity DataKi:  37nMAssay Description:Binding activity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]-clonidine as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Dog)
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM50061220(1-((S)-1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benz...)
Affinity DataKi:  39nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50027023(1-(3-Iodo-pyridin-2-yl)-piperazine | CHEMBL295764)
Affinity DataKi:  42nMAssay Description:Binding activity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]-clonidine as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
TBA

Curated by ChEMBL
LigandPNGBDBM31005(2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyraz...)
Affinity DataKi:  43nMAssay Description:Binding activity against alpha-1 adrenergic receptor from calf cerebral cortex, using [3H]-prazosin as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
TBA

Curated by ChEMBL
LigandPNGBDBM31005(2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyraz...)
Affinity DataKi:  43nMAssay Description:Displacement of [3H]-prazosin from calf cerebral cortex alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50013515((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)
Affinity DataKi:  49nMAssay Description:Evaluated for its ability to displace [3H]-clonidine from alpha-2 adrenergic receptor of calf cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50013515((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)
Affinity DataKi:  49nMAssay Description:Binding activity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]-clonidine as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50027031((2-Chloro-phenyl)-(4,5-dihydro-1H-imidazol-2-ylmet...)
Affinity DataKi:  55nMAssay Description:Binding affinity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]prazosin as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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