Affinity DataKi: 0.0330nMAssay Description:Binding affinity to human AChEMore data for this Ligand-Target Pair
Affinity DataKi: 0.0417nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 0.0537nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 0.0661nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 0.132nMAssay Description:Mixed inhibition of recombinant human AChE expressed in HEK293 cells assessed as dissociation constant for enzyme-inhibitor complex using varying lev...More data for this Ligand-Target Pair
Affinity DataKi: 0.258nMAssay Description:Mixed inhibition of recombinant human AChE expressed in HEK293 cells assessed as dissociation constant for enzyme-substrate-inhibitor complex using v...More data for this Ligand-Target Pair
Affinity DataKi: 0.324nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 0.977nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Competitive inhibition of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate assessed as dissociation constant for enzyme-inhibitor complex by Li...More data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate assessed as dissociation constant for enzyme-substrate-inhibitor com...More data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 7.80nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Universitat Aut£Noma De Barcelona
Curated by ChEMBL
Universitat Aut£Noma De Barcelona
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Non-competitive inhibition of rat liver mitochondrial MAO-B using phenylethylamine as substrate by Line-Weaver Burk plot analysisMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres (Iqog, Csic)
Curated by ChEMBL
Laboratorio De Radicales Libres (Iqog, Csic)
Curated by ChEMBL
Affinity DataKi: 20.2nMAssay Description:Inhibition of Electrophorus electricus AChE by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres (Iqog, Csic)
Curated by ChEMBL
Laboratorio De Radicales Libres (Iqog, Csic)
Curated by ChEMBL
Affinity DataKi: 38.9nMAssay Description:Inhibition of Electrophorus electricus AChE by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres (Iqog, Csic)
Curated by ChEMBL
Laboratorio De Radicales Libres (Iqog, Csic)
Curated by ChEMBL
Affinity DataKi: 41.9nMAssay Description:Inhibition of Electrophorus electricus AChE by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres (Iqog, Csic)
Curated by ChEMBL
Laboratorio De Radicales Libres (Iqog, Csic)
Curated by ChEMBL
Affinity DataKi: 61.3nMAssay Description:Inhibition of Electrophorus electricus AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataKi: 63nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres (Iqog, Csic)
Curated by ChEMBL
Laboratorio De Radicales Libres (Iqog, Csic)
Curated by ChEMBL
Affinity DataKi: 106nMAssay Description:Inhibition of Electrophorus electricus AChE by Ellman's methodMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
University Of Cagliari
Curated by ChEMBL
University Of Cagliari
Curated by ChEMBL
Affinity DataKi: 110nMAssay Description:Noncompetitive inhibition of rat brain FAAH using [3H]AEA as substrate after 10 mins by Dixon plot analysisMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres (Iqog, Csic)
Curated by ChEMBL
Laboratorio De Radicales Libres (Iqog, Csic)
Curated by ChEMBL
Affinity DataKi: 149nMAssay Description:Mixed type inhibition of Electrophorus electricus AchE using acetylthiocholine as substrate by Line-Weaver Burk plot analysisMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres (Iqog, Csic)
Curated by ChEMBL
Laboratorio De Radicales Libres (Iqog, Csic)
Curated by ChEMBL
Affinity DataKi: 157nMAssay Description:Inhibition of Electrophorus electricus AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 229nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
University Of Cagliari
Curated by ChEMBL
University Of Cagliari
Curated by ChEMBL
Affinity DataKi: 390nMAssay Description:Competitive inhibition of rat brain FAAH using [3H]AEA as substrate after 10 mins by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 537nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 537nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 603nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University Of Barcelona
Curated by ChEMBL
University Of Barcelona
Curated by ChEMBL
Affinity DataKi: 630nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in Sprague-Dawley rat brain cortical membrane after 3 hrsMore data for this Ligand-Target Pair
Affinity DataKi: 708nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 890nMAssay Description:Displacement of [N-methyl-11C]6-Me-BTA-1 from pre-aggregated amyloid beta (1 to 40) fibrils (unknown origin) after 30 mins by scintillation counting ...More data for this Ligand-Target Pair
Affinity DataKi: 1.18E+3nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 1.41E+3nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University Of Barcelona
Curated by ChEMBL
University Of Barcelona
Curated by ChEMBL
Affinity DataKi: 1.44E+3nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in Sprague-Dawley rat brain cortical membrane after 3 hrsMore data for this Ligand-Target Pair
Affinity DataKi: 2.24E+3nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 3.00E+3nMAssay Description:Mixed-type inhibition of B6CBAF1/J mouse brain FAAH using [3H]AEA as substrate after 10 mins by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.72E+3nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 4.57E+3nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 6.30E+3nMAssay Description:Mixed-type inhibition of B6CBAF1/J mouse brain FAAH using [3H]AEA as substrate after 10 mins by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 6.76E+3nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres (Iqog, Csic)
Curated by ChEMBL
Laboratorio De Radicales Libres (Iqog, Csic)
Curated by ChEMBL
Affinity DataKi: 6.80E+3nMAssay Description:Inhibition of Electrophorus electricus AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataKi: 6.92E+3nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 7.59E+3nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University Of Barcelona
Curated by ChEMBL
University Of Barcelona
Curated by ChEMBL
Affinity DataKi: 8.21E+3nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in Sprague-Dawley rat brain cortical membrane after 3 hrsMore data for this Ligand-Target Pair
Affinity DataKi: 9.55E+3nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
University Of Barcelona
Curated by ChEMBL
University Of Barcelona
Curated by ChEMBL
Affinity DataKi: 1.68E+4nMAssay Description:Inhibition of recombinant full length human G6PD expressed in Escherichia coli HB351 using G6P as substrate in presence of NADP+ by spectrofluorimetr...More data for this Ligand-Target Pair
Affinity DataKi: 1.86E+4nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair