Affinity DataKi: 0.0316nMAssay Description:Displacement of [3H]GR205171 from Mongolian gerbil brain NK1 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:In vitro competitive binding versus [3H]-citalopram in murine kidney cells transfected with cDNA for human serotonin transporter (SERT)More data for this Ligand-Target Pair
Affinity DataKi: 0.0501nMAssay Description:Displacement of [3H]substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0501nMAssay Description:Antagonist activity at human recombinant NK1 receptor expressed in human U20S cells assessed as effect on substance P-induced intracellular calcium l...More data for this Ligand-Target Pair
Affinity DataKi: 0.0631nMAssay Description:Displacement of [3H]SP from human recombinant NK1 receptor expressed in CHO cells after 40 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.0631nMAssay Description:Antagonist activity at human recombinant NK1 receptor expressed in human U20S cells assessed as effect on substance P-induced intracellular calcium l...More data for this Ligand-Target Pair
Affinity DataKi: 0.0646nMAssay Description:Displacement of [3H]SP from human recombinant NK1 receptor expressed in CHO cells after 40 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.0794nMAssay Description:Antagonist activity at human recombinant NK1 receptor expressed in human U20S cells assessed as effect on substance P-induced intracellular calcium l...More data for this Ligand-Target Pair
Affinity DataKi: 0.0794nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.0813nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Antagonist activity at human recombinant NK1 receptor expressed in human U20S cells assessed as effect on substance P-induced intracellular calcium l...More data for this Ligand-Target Pair
Affinity DataKi: 0.117nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.120nMAssay Description:Invitro competitive binding versus [N-methyl-3H]-WIN 35428 in murine kidney cells transfected with cDNA for human dopamine transporter (DAT)More data for this Ligand-Target Pair
Affinity DataKi: 0.126nMAssay Description:Displacement of [3H]GR205171 from human NK1 receptor in cortex homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.138nMAssay Description:Displacement of [3H]SP from human recombinant NK1 receptor expressed in CHO cells after 40 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.141nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.158nMAssay Description:Antagonist activity at human recombinant NK1 receptor expressed in human U20S cells assessed as effect on substance P-induced intracellular calcium l...More data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.178nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]SP from human recombinant NK1 receptor expressed in CHO cells after 40 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.209nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.224nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.224nMAssay Description:Displacement of [3H]substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.240nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.251nMAssay Description:Antagonist activity at human recombinant NK1 receptor expressed in human U20S cells assessed as effect on substance P-induced intracellular calcium l...More data for this Ligand-Target Pair
Affinity DataKi: 0.251nMAssay Description:Antagonist activity at human recombinant NK1 receptor expressed in human U20S cells assessed as effect on substance P-induced intracellular calcium l...More data for this Ligand-Target Pair
Affinity DataKi: 0.251nMAssay Description:Antagonist activity at human recombinant NK1 receptor expressed in human U20S cells assessed as effect on substance P-induced intracellular calcium l...More data for this Ligand-Target Pair
Affinity DataKi: 0.251nMAssay Description:Antagonist activity at human recombinant NK1 receptor expressed in human U20S cells assessed as effect on substance P-induced intracellular calcium l...More data for this Ligand-Target Pair
Affinity DataKi: 0.251nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.275nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.316nMAssay Description:Antagonist activity at human recombinant NK1 receptor expressed in human U20S cells assessed as effect on substance P-induced intracellular calcium l...More data for this Ligand-Target Pair
Affinity DataKi: 0.324nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.331nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Lublin
Curated by ChEMBL
Medical University Of Lublin
Curated by ChEMBL
Affinity DataKi: 0.340nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.360nMAssay Description:Competitive binding versus [N-methyl-3H]-WIN 35,428 in murine kidney cells transfected with human dopamine transporterMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Medical University Of Lublin
Curated by ChEMBL
Medical University Of Lublin
Curated by ChEMBL
Affinity DataKi: 0.370nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in HEK293 cell membranes measured after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.427nMAssay Description:Displacement of [3H]substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.437nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.480nMAssay Description:In vitro affinity determined using [3H]-WIN- 35428 in murine kidney cells transfected with human dopamine transporter (DAT)More data for this Ligand-Target Pair
Affinity DataKi: 0.480nMAssay Description:In vitro competitive binding versus [N-methyl-3H]-WIN 35428 in murine kidney cells transfected with cDNA for human dopamine transporter (DAT)More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 0.490nMAssay Description:Invitro competitive binding versus [N-methyl-3H]-WIN 35428 in murine kidney cells transfected with cDNA for human dopamine transporter (DAT)More data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Antagonist activity at human recombinant NK1 receptor expressed in human U20S cells assessed as effect on substance P-induced intracellular calcium l...More data for this Ligand-Target Pair
Affinity DataKi: 0.537nMAssay Description:Displacement of [3H]substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.646nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.670nMAssay Description:In vitro affinity determined using [3H]-citalopram in murine kidney cells transfected with human serotonin transporter (SERT)More data for this Ligand-Target Pair