Found 186 with Last Name = 'ma' and Initial = 'ya' 
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
3D Structure (crystal)TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Induction of internalization of HA-tagged human S1P1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human mPGES-1 expressed in Escherichia coli Rosetta microsomes assessed as reduction in conversion of PGH2 to PGE2 incubate...More data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 6.10nMAssay Description:Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 7.10nMAssay Description:Inhibition of mouse GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 8.5nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 9.10nMAssay Description:Inhibition of rat GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 9.10nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 9.20nMAssay Description:Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human EGFR L858R mutant expressed in baculovirus infected insect cells preincubated for 5 mins followed by ATP addition and...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of EGFR in human HepG2 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in interleukin-1 beta-induced PGE2 production incubated for 30 mins followed by IL-1b...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in interleukin-1 beta-induced PGE2 production incubated for 30 mins followed by IL-1b...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in interleukin-1 beta-induced PGE2 production incubated for 30 mins followed by IL-1b...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in interleukin-1 beta-induced PGE2 production incubated for 30 mins followed by IL-1b...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant membrane bound mPGES-1 assessed as reduction in conversion of PGH2 to PGE2 by measuring MDA and 12-HHT formation by f...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of EGFR in human HepG2 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
