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Found 169 with Last Name = 'maddileti' and Initial = 's'
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50373326(CHEMBL444278)
Affinity DataKi:  0.780nMAssay Description:Inhibition of [3H]-5 binding to P2Y purinoceptor 1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50409757(CHEMBL2112864)
Affinity DataKi:  2.5nMAssay Description:Inhibition of [3H]-5 binding to P2Y purinoceptor 1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50409764(CHEMBL2112867)
Affinity DataKi:  3.60nMAssay Description:Inhibition of [3H]-5 binding to P2Y purinoceptor 1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50134963(CHEMBL146342 | Phosphoric acid mono-[(1R,5S)-4-(2-...)
Affinity DataKi:  5.10nMAssay Description:Inhibition of [3H]-5 binding to P2Y purinoceptor 1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50134966(CHEMBL343651 | Phosphoric acid mono-[(1R,5S)-4-(6-...)
Affinity DataKi:  12.6nMAssay Description:Inhibition of [3H]-5 binding to P2Y purinoceptor 1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50409761(CHEMBL2112863)
Affinity DataKi:  17.6nMAssay Description:Inhibition of [3H]-5 binding to P2Y purinoceptor 1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50134967(CHEMBL356041 | Phosphoric acid mono-[(1R,5S)-4-(6-...)
Affinity DataKi:  35nMAssay Description:Inhibition of [3H]-5 binding to P2Y purinoceptor 1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50409759(CHEMBL2112868)
Affinity DataKi:  45nMAssay Description:Inhibition of [3H]-5 binding to P2Y purinoceptor 1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50215404(CHEMBL227235 | [3-(2-iodo-6-methylaminopurin-9-yl)...)
Affinity DataKi:  66nMAssay Description:Displacement of [3H]MRS2270 from human P2Y1 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50121987(CHEMBL153254 | [3-(2-Chloro-6-methylamino-purin-9-...)
Affinity DataKi:  76nMAssay Description:Displacement of [3H]MRS2270 from human P2Y1 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50409758(CHEMBL2112869)
Affinity DataKi:  80nMAssay Description:Inhibition of [3H]-5 binding to P2Y purinoceptor 1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50409762(CHEMBL2112865)
Affinity DataKi:  91nMAssay Description:Inhibition of [3H]-5 binding to P2Y purinoceptor 1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50215406((1'R,2'S,4'S,5'S)-4-(2-ethynyl-6-methylaminopurin-...)
Affinity DataKi:  95nMAssay Description:Displacement of [3H]MRS2270 from human P2Y1 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50215400((1'R,2'S,4'R,5'S)-phosphoric acid mono-[4-(6-methy...)
Affinity DataKi:  273nMAssay Description:Displacement of [3H]MRS2270 from human P2Y1 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50409756(CHEMBL2112866)
Affinity DataKi:  330nMAssay Description:Inhibition of [3H]-5 binding to P2Y purinoceptor 1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50409763(CHEMBL2112007)
Affinity DataKi:  430nMAssay Description:Inhibition of [3H]-5 binding to P2Y purinoceptor 1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50215402((1'R,2'S,4'R,5'S)-phosphoric acid mono-[4-(2-cyano...)
Affinity DataKi:  540nMAssay Description:Displacement of [3H]MRS2270 from human P2Y1 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50215403((1'R,2'S,4'R,5'S)-phosphoric acid mono-[4-(2-carba...)
Affinity DataKi:  650nMAssay Description:Displacement of [3H]MRS2270 from human P2Y1 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50215401((1'R,2'S,4'S,5'S)-phosphoric acid mono-[1-hydroxym...)
Affinity DataKi:  706nMAssay Description:Displacement of [3H]MRS2270 from human P2Y1 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50409760(CHEMBL2112861)
Affinity DataKi:  863nMAssay Description:Inhibition of [3H]-5 binding to P2Y purinoceptor 1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50215405((1'R,2'S,4'R,5'S)-6-methylamino-9-(4-phosphonooxy-...)
Affinity DataKi:  1.43E+3nMAssay Description:Displacement of [3H]MRS2270 from human P2Y1 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50373326(CHEMBL444278)
Affinity DataIC50:  8.40nMAssay Description:Antagonistic activity against P2Y purinoceptor 1More data for this Ligand-Target Pair
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50134963(CHEMBL146342 | Phosphoric acid mono-[(1R,5S)-4-(2-...)
Affinity DataIC50:  37nMAssay Description:Antagonistic activity against P2Y purinoceptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50409764(CHEMBL2112867)
Affinity DataIC50:  49nMAssay Description:Antagonistic activity against P2Y purinoceptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50409757(CHEMBL2112864)
Affinity DataIC50:  52nMAssay Description:Antagonistic activity against P2Y purinoceptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50118238(CHEMBL339873 | MRS 2279)
Affinity DataIC50:  52nMAssay Description:Antagonist activity against Turkey erythrocyte P2Y purinoceptor 1 (P2Y1) by the compound is measuredMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50134966(CHEMBL343651 | Phosphoric acid mono-[(1R,5S)-4-(6-...)
Affinity DataIC50:  87nMAssay Description:Antagonistic activity against P2Y purinoceptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50215406((1'R,2'S,4'S,5'S)-4-(2-ethynyl-6-methylaminopurin-...)
Affinity DataIC50:  93nMAssay Description:Antagonist activity at human P2Y1 receptor expressed in 1321N1 cells assessed as inhibition of 2-MeSADP-induced inositol phosphate formationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50215406((1'R,2'S,4'S,5'S)-4-(2-ethynyl-6-methylaminopurin-...)
Affinity DataIC50:  93nMAssay Description:Antagonist activity at human P2Y1 receptor expressed in 1321N1 cells assessed as inhibition of 2-MeS-ADP-stimulated PLC activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50409761(CHEMBL2112863)
Affinity DataIC50:  157nMAssay Description:Antagonistic activity against P2Y purinoceptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50076460(CHEMBL288798 | Phosphoric acid mono-[5-(2-chloro-6...)
Affinity DataIC50:  206nMAssay Description:Antagonist activity against Turkey erythrocyte P2Y purinoceptor 1 (P2Y1) by the compound is measuredMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50409762(CHEMBL2112865)
Affinity DataIC50:  221nMAssay Description:Antagonistic activity against P2Y purinoceptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50409759(CHEMBL2112868)
Affinity DataIC50:  356nMAssay Description:Antagonistic activity against P2Y purinoceptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50409760(CHEMBL2112861)
Affinity DataIC50:  367nMAssay Description:Antagonistic activity against P2Y purinoceptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50134967(CHEMBL356041 | Phosphoric acid mono-[(1R,5S)-4-(6-...)
Affinity DataIC50:  377nMAssay Description:Antagonistic activity against P2Y purinoceptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50409758(CHEMBL2112869)
Affinity DataIC50:  452nMAssay Description:Antagonistic activity against P2Y purinoceptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50121987(CHEMBL153254 | [3-(2-Chloro-6-methylamino-purin-9-...)
Affinity DataIC50:  617nMAssay Description:Antagonist activity at human P2Y1 receptor expressed in 1321N1 cells assessed as inhibition of 2-MeS-ADP-stimulated PLC activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50121987(CHEMBL153254 | [3-(2-Chloro-6-methylamino-purin-9-...)
Affinity DataIC50:  620nMAssay Description:Antagonist activity at human P2Y1 receptor expressed in 1321N1 cells assessed as inhibition of 2-MeSADP-induced inositol phosphate formationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50215404(CHEMBL227235 | [3-(2-iodo-6-methylaminopurin-9-yl)...)
Affinity DataIC50:  790nMAssay Description:Antagonist activity at human P2Y1 receptor expressed in 1321N1 cells assessed as inhibition of 2-MeSADP-induced inositol phosphate formationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50215404(CHEMBL227235 | [3-(2-iodo-6-methylaminopurin-9-yl)...)
Affinity DataIC50:  794nMAssay Description:Antagonist activity at human P2Y1 receptor expressed in 1321N1 cells assessed as inhibition of 2-MeS-ADP-stimulated PLC activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50215405((1'R,2'S,4'R,5'S)-6-methylamino-9-(4-phosphonooxy-...)
Affinity DataIC50:  870nMAssay Description:Antagonist activity at human P2Y1 receptor expressed in 1321N1 cells assessed as inhibition of 2-MeSADP-induced inositol phosphate formationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50215405((1'R,2'S,4'R,5'S)-6-methylamino-9-(4-phosphonooxy-...)
Affinity DataIC50:  871nMAssay Description:Antagonist activity at human P2Y1 receptor expressed in 1321N1 cells assessed as inhibition of 2-MeS-ADP-stimulated PLC activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50215401((1'R,2'S,4'S,5'S)-phosphoric acid mono-[1-hydroxym...)
Affinity DataIC50:  1.55E+3nMAssay Description:Antagonist activity at human P2Y1 receptor expressed in 1321N1 cells assessed as inhibition of 2-MeS-ADP-stimulated PLC activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50215401((1'R,2'S,4'S,5'S)-phosphoric acid mono-[1-hydroxym...)
Affinity DataIC50:  1.56E+3nMAssay Description:Antagonist activity at human P2Y1 receptor expressed in 1321N1 cells assessed as inhibition of 2-MeSADP-induced inositol phosphate formationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50215403((1'R,2'S,4'R,5'S)-phosphoric acid mono-[4-(2-carba...)
Affinity DataIC50:  1.74E+3nMAssay Description:Antagonist activity at human P2Y1 receptor expressed in 1321N1 cells assessed as inhibition of 2-MeS-ADP-stimulated PLC activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50215403((1'R,2'S,4'R,5'S)-phosphoric acid mono-[4-(2-carba...)
Affinity DataIC50:  1.75E+3nMAssay Description:Antagonist activity at human P2Y1 receptor expressed in 1321N1 cells assessed as inhibition of 2-MeSADP-induced inositol phosphate formationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50409756(CHEMBL2112866)
Affinity DataIC50:  1.87E+3nMAssay Description:Antagonistic activity against P2Y purinoceptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50215400((1'R,2'S,4'R,5'S)-phosphoric acid mono-[4-(6-methy...)
Affinity DataIC50:  1.94E+3nMAssay Description:Antagonist activity at human P2Y1 receptor expressed in 1321N1 cells assessed as inhibition of 2-MeSADP-induced inositol phosphate formationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50215400((1'R,2'S,4'R,5'S)-phosphoric acid mono-[4-(6-methy...)
Affinity DataIC50:  1.95E+3nMAssay Description:Antagonist activity at human P2Y1 receptor expressed in 1321N1 cells assessed as inhibition of 2-MeS-ADP-stimulated PLC activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50409763(CHEMBL2112007)
Affinity DataIC50:  2.40E+3nMAssay Description:Antagonistic activity against P2Y purinoceptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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