Affinity DataIC50: 25nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 126nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 126nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 251nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 251nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 398nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 398nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 631nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 794nMAssay Description:Inhibition of human Nav1.5More data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of rat Nav1.7 by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human Nav1.5More data for this Ligand-Target Pair
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of human Nav1.5More data for this Ligand-Target Pair
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of human Nav1.5More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of human Nav1.5More data for this Ligand-Target Pair
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of human Nav1.5More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of human ERG channel by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of human ERG channel by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of human Nav1.5More data for this Ligand-Target Pair
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of human Nav1.5More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of human ERG channel by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of human Nav1.5More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of human ERG channel by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of human Nav1.5More data for this Ligand-Target Pair
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of human Nav1.5More data for this Ligand-Target Pair
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of human Nav1.5More data for this Ligand-Target Pair
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of human Nav1.5More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of human ERG channel by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of human Nav1.5More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of human ERG channel by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.94E+3nMAssay Description:Inhibition of human Nav1.5More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 7.94E+3nMAssay Description:Inhibition of human ERG channel by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair