Compile Data Set for Download or QSAR
maximum 50k data
Found 73 with Last Name = 'mcintyre' and Initial = 'p'
TargetB2 bradykinin receptor(RAT)
Novartis Institute For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50370083(CHEMBL1907651)
Affinity DataKi:  0.0230nMAssay Description:Inhibition of specific binding of [3H]-BK (1 nM) to rat Bradykinin receptor B2 by 50% in NG108-15 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(RAT)
Novartis Institute For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50370077(CHEMBL1907652)
Affinity DataKi:  0.310nMAssay Description:Inhibition of specific binding of [3H]-BK (1 nM) to rat Bradykinin receptor B2 by 50% in NG108-15 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(RAT)
Novartis Institute For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50113263((S)-1-[4-(4-benzhydrylthiosemicarbazido)-3-nitrobe...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of specific binding of [3H]-BK (1 nM) to rat Bradykinin receptor B2 by 50% in NG108-15 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(RAT)
Novartis Institute For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50113263((S)-1-[4-(4-benzhydrylthiosemicarbazido)-3-nitrobe...)
Affinity DataKi:  0.600nMAssay Description:Inhibition of specific binding of [3H]-BK (1 nM) to rat Bradykinin receptor B2 by 50% in NG108-15 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
Novartis Institute For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50409527(CHEMBL2112283)
Affinity DataKi:  0.790nMAssay Description:Displacement of [3H]BK (1 nM) from human Bradykinin receptor B2 expressed in Cos-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50151885(1-[4-(2,2-Diphenyl-ethylamino)-3-(morpholine-4-car...)
Affinity DataKi:  1nMAssay Description:Binding affinity for Bradykinin receptor B1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
Novartis Institute For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50409529(CHEMBL2112221)
Affinity DataKi:  1.47nMAssay Description:Displacement of [3H]BK (1 nM) from human Bradykinin receptor B2 expressed in Cos-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
Novartis Institute For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50409528(CHEMBL2112220)
Affinity DataKi:  2.79nMAssay Description:Displacement of [3H]BK (1 nM) from human Bradykinin receptor B2 expressed in Cos-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
Novartis Institute For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50370080(CHEMBL1907656)
Affinity DataKi:  4.67nMAssay Description:Displacement of [3H]BK (1 nM) from human Bradykinin receptor B2 expressed in Cos-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(RAT)
Novartis Institute For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50370081(CHEMBL1907654)
Affinity DataKi:  5.46nMAssay Description:Inhibition of specific binding of [3H]-BK (1 nM) to rat Bradykinin receptor B2 by 50% in NG108-15 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(RAT)
Novartis Institute For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50370078(CHEMBL1907653)
Affinity DataKi:  7.30nMAssay Description:Inhibition of specific binding of [3H]-BK (1 nM) to rat Bradykinin receptor B2 by 50% in NG108-15 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50151884(CHEMBL185551 | N,N-Bis-(3-dimethylamino-propyl)-3-...)
Affinity DataKi:  10nMAssay Description:Binding affinity for Bradykinin receptor B1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50151886(CHEMBL181695 | {2-(2,2-Diphenyl-ethylamino)-5-[4-(...)
Affinity DataKi:  10nMAssay Description:Binding affinity for Bradykinin receptor B1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50151891(CHEMBL273869 | {2-(2,2-Diphenyl-ethylamino)-5-[4-(...)
Affinity DataKi:  10nMAssay Description:Binding affinity for Bradykinin receptor B1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50151894(1-[4-(2,2-Diphenyl-ethylamino)-3-nitro-benzenesulf...)
Affinity DataKi:  10nMAssay Description:Binding affinity for Bradykinin receptor B1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(RAT)
Novartis Institute For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50409527(CHEMBL2112283)
Affinity DataKi:  10.7nMAssay Description:Inhibition of specific binding of [3H]-BK (1 nM) to rat Bradykinin receptor B2 by 50% in NG108-15 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(RAT)
Novartis Institute For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50370080(CHEMBL1907656)
Affinity DataKi:  14.5nMAssay Description:Inhibition of specific binding of [3H]-BK (1 nM) to rat Bradykinin receptor B2 by 50% in NG108-15 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
Novartis Institute For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50370081(CHEMBL1907654)
Affinity DataKi:  34.1nMAssay Description:Displacement of [3H]BK (1 nM) from human Bradykinin receptor B2 expressed in Cos-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(RAT)
Novartis Institute For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50409529(CHEMBL2112221)
Affinity DataKi:  64.5nMAssay Description:Inhibition of specific binding of [3H]-BK (1 nM) to rat Bradykinin receptor B2 by 50% in NG108-15 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
Novartis Institute For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50370077(CHEMBL1907652)
Affinity DataKi:  95nMAssay Description:Displacement of [3H]BK (1 nM) from human Bradykinin receptor B2 expressed in Cos-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
Novartis Institute For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50370083(CHEMBL1907651)
Affinity DataKi:  119nMAssay Description:Displacement of [3H]BK (1 nM) from human Bradykinin receptor B2 expressed in Cos-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50151888(3-[3-Acetyl-4-(2,2-diphenyl-ethylamino)-benzenesul...)
Affinity DataKi:  130nMAssay Description:Binding affinity for Bradykinin receptor B1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50151889(CHEMBL180143 | N,N-Bis-(3-dimethylamino-propyl)-3-...)
Affinity DataKi:  140nMAssay Description:Binding affinity for Bradykinin receptor B1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(RAT)
Novartis Institute For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50409528(CHEMBL2112220)
Affinity DataKi:  176nMAssay Description:Inhibition of specific binding of [3H]-BK (1 nM) to rat Bradykinin receptor B2 by 50% in NG108-15 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50151890(CHEMBL181098 | N,N-Bis-(3-dimethylamino-propyl)-4-...)
Affinity DataKi:  230nMAssay Description:Binding affinity for Bradykinin receptor B1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
Novartis Institute For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50113264(1-[4-(4-benzhydrylthiosemicarbazido)-3-nitrobenzen...)
Affinity DataKi:  237nMAssay Description:Displacement of [3H]BK (1 nM) from human Bradykinin receptor B2 expressed in Cos-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50151893(4-(1-Benzyl-2-phenyl-ethylamino)-N,N-bis-(3-dimeth...)
Affinity DataKi:  250nMAssay Description:Binding affinity for Bradykinin receptor B1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
Novartis Institute For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50409530(CHEMBL2112219)
Affinity DataKi:  253nMAssay Description:Displacement of [3H]BK (1 nM) from human Bradykinin receptor B2 expressed in Cos-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
Novartis Institute For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50370082(CHEMBL1907655)
Affinity DataKi:  299nMAssay Description:Displacement of [3H]BK (1 nM) from human Bradykinin receptor B2 expressed in Cos-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
Novartis Institute For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50370084(CHEMBL1907657)
Affinity DataKi:  645nMAssay Description:Displacement of [3H]BK (1 nM) from human Bradykinin receptor B2 expressed in Cos-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(RAT)
Novartis Institute For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50370082(CHEMBL1907655)
Affinity DataKi:  654nMAssay Description:Inhibition of specific binding of [3H]-BK (1 nM) to rat Bradykinin receptor B2 by 50% in NG108-15 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
Novartis Institute For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50113263((S)-1-[4-(4-benzhydrylthiosemicarbazido)-3-nitrobe...)
Affinity DataKi:  772nMAssay Description:Displacement of [3H]BK (1 nM) from human Bradykinin receptor B2 expressed in Cos-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50151892(3-[3-Chloro-4-(2,2-diphenyl-ethylamino)-benzenesul...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity for Bradykinin receptor B1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
Novartis Institute For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50151887(4-(Benzhydryl-amino)-N,N-bis-(3-dimethylamino-prop...)
Affinity DataKi:  1.40E+3nMAssay Description:Binding affinity for Bradykinin receptor B2 expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
Novartis Institute For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50113263((S)-1-[4-(4-benzhydrylthiosemicarbazido)-3-nitrobe...)
Affinity DataKi:  1.43E+3nMAssay Description:Displacement of [3H]BK (1 nM) from human Bradykinin receptor B2 expressed in Cos-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50151887(4-(Benzhydryl-amino)-N,N-bis-(3-dimethylamino-prop...)
Affinity DataKi:  3.00E+3nMAssay Description:Binding affinity for Bradykinin receptor B1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(RAT)
Novartis Institute For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50409528(CHEMBL2112220)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of Bradykinin receptor B2-mediated contractions of rat uterus smooth muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(RAT)
Novartis Institute For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50409527(CHEMBL2112283)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of Bradykinin receptor B2-mediated contractions of rat uterus smooth muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
Novartis Institute For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50409528(CHEMBL2112220)
Affinity DataIC50:  12nMAssay Description:Antagonism of the [Ca2+] efflux actions of the human Bradykinin receptor B2 (SK-N-SH neuroblastoma)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50180699(6(4-chloro-3-ethoxy-phenyl)-7-isopropyl-2-methyl-3...)
Affinity DataIC50:  12nMAssay Description:Inhibition of calcium influx evoked by capsaicin in human TRPV1 expressing cells by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50180715(6-(4-chloro-phenyl)-7-isopropyl-2-methyl-3H-quinaz...)
Affinity DataIC50:  13nMAssay Description:Inhibition of calcium influx evoked by capsaicin in human TRPV1 expressing cells by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50180717(6(4-chloro-3-methoxy-phenyl)-7-isopropyl-2-methyl-...)
Affinity DataIC50:  14nMAssay Description:Inhibition of calcium influx evoked by capsaicin in human TRPV1 expressing cells by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
Novartis Institute For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50409527(CHEMBL2112283)
Affinity DataIC50:  17nMAssay Description:Antagonism of the [Ca2+] efflux actions of human Bradykinin receptor B2 (WI38 fibroblasts)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50180711(7-tert-butyl-6-(4-chloro-phenyl)-2-thioxo-2,3-dihy...)
Affinity DataIC50:  18nMAssay Description:Inhibition of low pH activation of human TRPV1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50180706(6-(4-chloro-3fluoro-phenyl)-7-isopropyl-2-methyl-3...)
Affinity DataIC50:  23nMAssay Description:Inhibition of calcium influx evoked by capsaicin in human TRPV1 expressing cells by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50180708(7-tert-butyl-6-phenyl-2-thioxo-2,3-dihydro-1H-pyri...)
Affinity DataIC50:  25nMAssay Description:Inhibition of low pH activation of rat TRPV1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50180698(6-1,3-benzdioxolo-5-yl-7-isopropyl-2-methyl-3H-qui...)
Affinity DataIC50:  31nMAssay Description:Inhibition of calcium influx evoked by capsaicin in human TRPV1 expressing cells by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50180719(6-(2,4-dichloro-5-ethoxy-phenyl)-7-isopropyl-2-met...)
Affinity DataIC50:  37nMAssay Description:Inhibition of calcium influx evoked by capsaicin in human TRPV1 expressing cells by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50180701(6(4-chloro-3-propoxy-phenyl)-7-isopropyl-2-methyl-...)
Affinity DataIC50:  40nMAssay Description:Inhibition of calcium influx evoked by capsaicin in human TRPV1 expressing cells by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50180703(6(3-chloro-4-methyl-phenyl)-7-isopropyl-2-methyl-3...)
Affinity DataIC50:  42nMAssay Description:Inhibition of calcium influx evoked by capsaicin in human TRPV1 expressing cells by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 73 total ) | Next | Last >>
Jump to: