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Found 611 with Last Name = 'mckinzie' and Initial = 'dl'
TargetKappa-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130563((3R)-7-Hydroxy-N-[(1S)-1-{[(3R,4R)-4-(3-hydroxyphe...)
Affinity DataKi:  0.0591nMAssay Description:Displacement of [3H]diprenorphine from human opioid kappa receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM86231(ATR | ATROPINE | Atropine,(-) | CAS_51-55-8 | CHEM...)
Affinity DataKi:  0.100nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM86231(ATR | ATROPINE | Atropine,(-) | CAS_51-55-8 | CHEM...)
Affinity DataKi:  0.100nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM82551(C18130 | CAS_105618-26-6 | NOR-BNI (HCI)2 | NORBNI)
Affinity DataKi:  0.153nMAssay Description:Displacement of [3H]diprenorphine from human opioid kappa receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50026614(CHEMBL575508)
Affinity DataKi:  0.153nMAssay Description:Displacement of [3H]diprenorphine from human opioid kappa receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM86231(ATR | ATROPINE | Atropine,(-) | CAS_51-55-8 | CHEM...)
Affinity DataKi:  0.200nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM86231(ATR | ATROPINE | Atropine,(-) | CAS_51-55-8 | CHEM...)
Affinity DataKi:  0.200nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM86231(ATR | ATROPINE | Atropine,(-) | CAS_51-55-8 | CHEM...)
Affinity DataKi:  0.300nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM86231(ATR | ATROPINE | Atropine,(-) | CAS_51-55-8 | CHEM...)
Affinity DataKi:  0.400nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50244204(CHEMBL4071962)
Affinity DataKi:  0.470nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in HEK cell membranes after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM86231(ATR | ATROPINE | Atropine,(-) | CAS_51-55-8 | CHEM...)
Affinity DataKi:  0.5nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50346474((R)-4-[2-(3,4-Dichloro-phenyl)-acetyl]-3-pyrrolidi...)
Affinity DataKi:  0.502nMAssay Description:Displacement of [3H]diprenorphine from human opioid kappa receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50358169(CHEMBL1921845)
Affinity DataKi:  0.565nMAssay Description:Displacement of [3H]diprenorphine from human opioid kappa receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM86231(ATR | ATROPINE | Atropine,(-) | CAS_51-55-8 | CHEM...)
Affinity DataKi:  0.600nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50358168(CHEMBL1921844)
Affinity DataKi:  0.617nMAssay Description:Displacement of [3H]diprenorphine from human opioid kappa receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50358165(CHEMBL1921841)
Affinity DataKi:  0.622nMAssay Description:Displacement of [3H]diprenorphine from human opioid kappa receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM86231(ATR | ATROPINE | Atropine,(-) | CAS_51-55-8 | CHEM...)
Affinity DataKi:  0.700nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50358166(CHEMBL1921842)
Affinity DataKi:  0.722nMAssay Description:Displacement of [3H]diprenorphine from human opioid kappa receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM86231(ATR | ATROPINE | Atropine,(-) | CAS_51-55-8 | CHEM...)
Affinity DataKi:  0.800nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM86231(ATR | ATROPINE | Atropine,(-) | CAS_51-55-8 | CHEM...)
Affinity DataKi:  0.900nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50244219(CHEMBL4081453)
Affinity DataKi:  0.927nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor from bovine hippocampus, used [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50358171(CHEMBL1921847)
Affinity DataKi:  0.949nMAssay Description:Displacement of [3H]diprenorphine from human opioid kappa receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM86231(ATR | ATROPINE | Atropine,(-) | CAS_51-55-8 | CHEM...)
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM86231(ATR | ATROPINE | Atropine,(-) | CAS_51-55-8 | CHEM...)
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM86231(ATR | ATROPINE | Atropine,(-) | CAS_51-55-8 | CHEM...)
Affinity DataKi:  1.10nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50358161(CHEMBL1921850)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]diprenorphine from human opioid kappa receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM22869(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
Affinity DataKi:  1.40nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50358160(CHEMBL1921849)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]diprenorphine from human opioid kappa receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM86231(ATR | ATROPINE | Atropine,(-) | CAS_51-55-8 | CHEM...)
Affinity DataKi:  1.5nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50358164(CHEMBL1921840)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]diprenorphine from human opioid kappa receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(GUINEA PIG)
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM86231(ATR | ATROPINE | Atropine,(-) | CAS_51-55-8 | CHEM...)
Affinity DataKi:  1.70nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50244218(CHEMBL4068189)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in HEK cell membranes after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50219916(6-(4-((benzylamino)methyl)phenoxy)nicotinamide | C...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]diprenorphine from human opioid kappa receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM82479(CAS_132539-06-1 | NSC_4585 | OLANZAPINE | USRE4934...)
Affinity DataKi:  1.90nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM22869(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
Affinity DataKi:  1.90nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50244206(CHEMBL4091203)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in HEK cell membranes after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50244202(CHEMBL4091735)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in HEK cell membranes after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50244203(CHEMBL4095567)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in HEK cell membranes after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50219916(6-(4-((benzylamino)methyl)phenoxy)nicotinamide | C...)
Affinity DataKi:  2.40nMAssay Description:Displacement of [3H]diprenorphine from human opioid mu receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM82479(CAS_132539-06-1 | NSC_4585 | OLANZAPINE | USRE4934...)
Affinity DataKi:  2.5nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM50002338((Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethy...)
Affinity DataKi:  2.70nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50244221(CHEMBL4063336)
Affinity DataKi:  4.30nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor from bovine hippocampus, used [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50244188(CHEMBL4061162)
Affinity DataKi:  4.60nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in HEK cell membranes after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM22869(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50244207(CHEMBL4090293)
Affinity DataKi:  5.80nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in HEK cell membranes after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM82479(CAS_132539-06-1 | NSC_4585 | OLANZAPINE | USRE4934...)
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM22869(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM82551(C18130 | CAS_105618-26-6 | NOR-BNI (HCI)2 | NORBNI)
Affinity DataKi:  6.60nMAssay Description:Displacement of [3H]diprenorphine from human opioid delta receptor expressed in HEK293 cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50244210(CHEMBL4095995)
Affinity DataKi:  6.80nMAssay Description:Compound was tested for antagonistic activity against D2 receptor from rat striatum, used [3H]raclopride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM22869(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
In DepthDetails ArticlePubMed
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