TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
Universita Degli Studi Di Milano
Universita Degli Studi Di Milano
Affinity DataKi: 25nM ΔG°: -43.1kJ/mole IC50: 460nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...More data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
Universita Degli Studi Di Milano
Universita Degli Studi Di Milano
Affinity DataKi: 61nM ΔG°: -40.9kJ/mole IC50: 530nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...More data for this Ligand-Target Pair
Affinity DataKi: 220nM ΔG°: -37.6kJ/mole IC50: 250nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...More data for this Ligand-Target Pair
Affinity DataKi: 250nM ΔG°: -37.3kJ/mole IC50: 270nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...More data for this Ligand-Target Pair
Affinity DataKi: 252nMAssay Description:Mixed type inhibition of DENV3 NS5 RdRp using increasing concentration of GTP as substrate assessed as free enzyme after 1 hr in presence of ss-RNA P...More data for this Ligand-Target Pair
Affinity DataKi: 420nM ΔG°: -36.0kJ/mole IC50: 460nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...More data for this Ligand-Target Pair
Affinity DataKi: 870nM ΔG°: -34.2kJ/mole IC50: 970nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...More data for this Ligand-Target Pair
Affinity DataKi: 1.54E+3nMAssay Description:Mixed type inhibition of DENV3 NS5 RdRp using increasing concentration of ss-RNA PolyC as template assessed as free enzyme after 1 hr in presence of ...More data for this Ligand-Target Pair
Affinity DataKi: 1.58E+3nMAssay Description:Mixed type inhibition of DENV3 NS5 RdRp using increasing concentration of GTP as substrate assessed as enzyme-substrate complex after 1 hr in presenc...More data for this Ligand-Target Pair
Affinity DataKi: 4.33E+3nMAssay Description:Mixed type inhibition of DENV3 NS5 RdRp using increasing concentration of ss-RNA PolyC as template assessed as enzyme-substrate complex after 1 hr in...More data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Displacement of Smac-1F from human His-tagged XIAP linker BIR2-BIR3 linker (124 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Displacement of Smac-1F from human His-tagged XIAP linker BIR2-BIR3 linker (124 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Displacement of Smac-1F from human His-tagged XIAP linker BIR2-BIR3 linker (124 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Displacement of Smac-1F from human His-tagged XIAP linker BIR2-BIR3 linker (124 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 3.90nMAssay Description:Displacement of Smac-1F from human His-tagged XIAP linker BIR2-BIR3 linker (124 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 4.40nMAssay Description:Displacement of Smac-1F from human His-tagged XIAP linker BIR2-BIR3 linker (124 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 5.30nMAssay Description:Displacement of Smac-1F from human His-tagged XIAP linker BIR2-BIR3 linker (124 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 5.40nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 5.90nMAssay Description:Displacement of Smac-1F from human His-tagged XIAP linker BIR2-BIR3 linker (124 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 8.40nMAssay Description:Displacement of Smac-1F from human His-tagged XIAP linker BIR2-BIR3 linker (124 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 12.6nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 15.5nMAssay Description:Displacement of Smac-1F from human His-tagged XIAP linker BIR2-BIR3 linker (124 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 15.5nMAssay Description:Displacement of Smac-1F from human His-tagged XIAP linker BIR2-BIR3 linker (124 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of DENV3 full length NS5 RdRp assessed as decrease in dsRNA levels preincubated for 20 mins followed by ss-RNA and ATTO-CTP, ATP, GTP and ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 16.2nMAssay Description:Displacement of Smac-1F from human His-tagged XIAP linker BIR2-BIR3 linker (124 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 17.6nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 24.5nMAssay Description:Displacement of FITC-Smac from human His-tagged XIAP BIR3 domain (241 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 24.9nMAssay Description:Displacement of FITC-Smac from human His-tagged XIAP BIR3 domain (241 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 25.4nMAssay Description:Displacement of FITC-Smac from human His-tagged XIAP BIR3 domain (241 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Displacement of FITC-Smac from human His-tagged XIAP BIR3 domain (241 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 26.7nMAssay Description:Displacement of FITC-Smac from human His-tagged XIAP BIR3 domain (241 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 29.7nMAssay Description:Displacement of FITC-Smac from human His-tagged XIAP BIR3 domain (241 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 29.9nMAssay Description:Displacement of FITC-Smac from human His-tagged XIAP BIR3 domain (241 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 31.1nMAssay Description:Displacement of FITC-Smac from human His-tagged XIAP BIR3 domain (241 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 31.2nMAssay Description:Displacement of FITC-Smac from human His-tagged XIAP BIR3 domain (241 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair