Compile Data Set for Download or QSAR
maximum 50k data
Found 2977 with Last Name = 'miller' and Initial = 'w'
TargetNociceptin receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50121249(CHEMBL415845 | F-G-G-F-T-G-A-R-K-S-A-R-K-L-Aib-N-Q...)
Affinity DataKi:  0.0200nMAssay Description:Affinity for human Opioid receptor like 1 (ORL-1) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50121247(CHEMBL414542 | F-G-G-F-T-G-Aib-R-K-S-A-R-K-L-A-N-Q...)
Affinity DataKi:  0.0500nMAssay Description:Affinity for human Opioid receptor like 1 (ORL-1) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50121245(CHEMBL266191 | F-G-G-F-T-G-Aib-R-K-S-Aib-R-K-L-A-N...)
Affinity DataKi:  0.0500nMAssay Description:Affinity for human Opioid receptor like 1 (ORL-1) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50121246(CHEMBL438537 | F-G-G-F-T-G-A-R-K-S-A-R-K-L-MeA-N-Q...)
Affinity DataKi:  0.0600nMAssay Description:Affinity for human Opioid receptor like 1 (ORL-1) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50121253(CHEMBL408356 | F-G-G-F-T-G-A-R-K-S-Aib-R-K-L-A-N-Q...)
Affinity DataKi:  0.0800nMAssay Description:Affinity for human Opioid receptor like 1 (ORL-1) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50121244(CHEMBL264084 | F-G-G-F-T-G-Aib-R-K-S-A-R-K-L-A-N-Q...)
Affinity DataKi:  0.100nMAssay Description:Affinity for human Opioid receptor like 1 (ORL-1) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153608(4-[4-Hydroxy-4-(3-trifluoromethyl-phenyl)-piperidi...)
Affinity DataKi:  0.110nMAssay Description:Binding affinity for recombinant human mu-opioid receptor was determined by using [3H]- diprenophine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50017686(4-[4-(4-Chloro-3-trifluoromethyl-phenyl)-4-hydroxy...)
Affinity DataKi:  0.110nMAssay Description:Binding affinity for recombinant human mu-opioid receptor was determined by using [3H]- diprenophine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50121256(CHEMBL410979 | F-G-G-F-T-G-A-R-K-S-A-R-K-L-Aib-N-Q...)
Affinity DataKi:  0.150nMAssay Description:Affinity for human Opioid receptor like 1 (ORL-1) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153614(4-[4-Hydroxy-4-(3-trifluoromethyl-phenyl)-piperidi...)
Affinity DataKi:  0.160nMAssay Description:Binding affinity for recombinant human mu-opioid receptor was determined by using [3H]- diprenophine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM86492(CAS_170713-75-4 | NSC_6324645 | Nociceptin)
Affinity DataKi:  0.180nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50004178(Nociceptin | Nociceptin/orphanin FQ | ORPHANIN FQ)
Affinity DataKi:  0.180nMAssay Description:Inhibition of [3H]nociceptin binding to human Opioid receptor like 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50316184(4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-6-((S)-3-amino...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50316183(4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-6-((R)-2-amino...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153611(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2...)
Affinity DataKi:  0.230nMAssay Description:Binding affinity for recombinant human mu-opioid receptor was determined by using [3H]- diprenophine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM21842((2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2...)
Affinity DataKi:  0.300nMAssay Description:Affinity for human Opioid receptor like 1 (ORL-1) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153613(4-[4-(4-Chloro-3-trifluoromethyl-phenyl)-4-hydroxy...)
Affinity DataKi:  0.300nMAssay Description:Binding affinity for recombinant human mu-opioid receptor was determined by using [3H]- diprenophine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50316192(4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-6-((R)-2-amino...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50121250(CHEMBL415584 | F-G-G-F-T-G-A-R-K-S-Aib-R-K-L-A-N-Q...)
Affinity DataKi:  0.480nMAssay Description:Affinity for human Opioid receptor like 1 (ORL-1) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50017698(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N,N...)
Affinity DataKi:  0.530nMAssay Description:Binding affinity for recombinant human mu-opioid receptor was determined by using [3H]- diprenophine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetVasopressin V1b receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299343((2S,4R)-1-((R)-5-chloro-1-(2,4-dimethoxyphenylsulf...)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]Arg8-vasopressin from human vasopressin V1b receptor expressed in CHO-K1 cells by Packard Topcount scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM86491(DiPOA | [8-(3,3-Diphenyl-propyl)-4-oxo-1-phenyl-1,...)
Affinity DataKi:  0.760nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083761(CHEMBL87429 | [3-Oxo-8-[3-(pyridin-2-ylamino)-prop...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity for Vitronectin receptor (alpha V beta 3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50132647(1-(3,3-Diphenyl-propyl)-4-(3-trifluoromethyl-pheny...)
Affinity DataKi:  1nMAssay Description:Binding affinity for recombinant human mu-opioid receptor was determined by using [3H]- diprenophine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1b receptor(RAT)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299343((2S,4R)-1-((R)-5-chloro-1-(2,4-dimethoxyphenylsulf...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]Arg8-vasopressin from rat vasopressin V1b receptor expressed in CHO-K1 cells by Packard Topcount scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50316184(4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-6-((S)-3-amino...)
Affinity DataKi:  1nMAssay Description:Inhibition of AKT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM25013(4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S...)
Affinity DataKi:  1nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288109(CHEMBL82123 | {2-Benzyl-7-[methyl-(2-piperidin-4-y...)
Affinity DataKi:  1nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50132647(1-(3,3-Diphenyl-propyl)-4-(3-trifluoromethyl-pheny...)
Affinity DataKi:  1nMAssay Description:Antagonistic activity against opioid receptor mu1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50121248(CHEMBL436732 | F-G-G-F-T-G-A-R-K-S-A-R-K-L-MeA-N-Q...)
Affinity DataKi:  1.10nMAssay Description:Affinity for human Opioid receptor like 1 (ORL-1) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083763(CHEMBL86992 | [(S)-8-[2-(6-Methylamino-pyridin-2-y...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity for Vitronectin receptor (alpha V beta 3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078714(CHEMBL288493 | SB-265123 | {(S)-3-[3-(Pyridin-2-yl...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity for non-peptide Vitronectin receptor (alpha V beta 3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288120(CHEMBL313768 | {2-Cyclohexyl-7-[methyl-(2-piperidi...)
Affinity DataKi:  1.30nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083764(CHEMBL421533 | [3-Oxo-8-[3-(pyridin-2-ylamino)-pro...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity for Vitronectin receptor (alpha V beta 3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50054826(CHEMBL144474 | [7-([4,4']Bipiperidinyl-1-carbonyl)...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078697(CHEMBL54138 | {(S)-7-[2-(1H-Imidazol-2-ylamino)-et...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity towards human Vitronectin receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288119(CHEMBL84073 | {2-Butyl-7-[methyl-(2-piperidin-4-yl...)
Affinity DataKi:  1.5nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50074035(CHEMBL82980 | {7-[(4-Carbamimidoyl-phenyl)-methyl-...)
Affinity DataKi:  1.5nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50074035(CHEMBL82980 | {7-[(4-Carbamimidoyl-phenyl)-methyl-...)
Affinity DataKi:  1.5nMAssay Description:Fibrinogen receptor binding affinity was determined by assaying for inhibition of [3H]-1 binding to purified Fibrinogen Receptor isolated from human...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288118(CHEMBL312122 | {2-Methyl-7-[methyl-(2-piperidin-4-...)
Affinity DataKi:  1.5nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288115(CHEMBL82746 | {2-(3-Methyl-butyl)-7-[methyl-(2-pip...)
Affinity DataKi:  1.5nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072493(CHEMBL108490 | [(S)-7-[(1H-Benzoimidazol-2-ylmethy...)
Affinity DataKi:  1.60nMAssay Description:Affinity for alphaIIb-beta3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50054827(CHEMBL85094 | SB-208651 | {8-[(4-Carbamimidoyl-phe...)
Affinity DataKi:  1.60nMAssay Description:Fibrinogen receptor binding affinity was determined by assaying for inhibition of [3H]-1 binding to purified Fibrinogen Receptor isolated from human...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50054827(CHEMBL85094 | SB-208651 | {8-[(4-Carbamimidoyl-phe...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50054827(CHEMBL85094 | SB-208651 | {8-[(4-Carbamimidoyl-phe...)
Affinity DataKi:  1.60nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288117(CHEMBL83756 | {2-[2-(4-Fluoro-phenyl)-ethyl]-7-[me...)
Affinity DataKi:  1.70nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083762(CHEMBL314022 | {2-Methyl-3-oxo-8-[3-(pyridin-2-yla...)
Affinity DataKi:  1.90nMAssay Description:Binding affinity for Vitronectin receptor (alpha V beta 3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50316185(4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-6-((R)-3-amino...)
Affinity DataKi:  1.90nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50074030(CHEMBL356020 | {8-[Methyl-(2-piperidin-4-yl-ethyl)...)
Affinity DataKi:  1.90nMAssay Description:Fibrinogen receptor binding affinity was determined by assaying for inhibition of [3H]-1 binding to purified Fibrinogen Receptor isolated from human...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072492(CHEMBL419180 | {(S)-7-[(1H-Benzoimidazol-2-ylmethy...)
Affinity DataKi:  1.90nMAssay Description:Effect against adhesion of HEK 293 cells transfected with human alpha-v beta-3 to vitronectin coated platesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 2977 total ) | Next | Last >>
Jump to: