Affinity DataKi: 0.0316nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human cloned muscarinic M3 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.316nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic acetylcholine M1 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories
Curated by ChEMBL
Smith Kline & French Laboratories
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Binding affinity of compound towards Vasopressin receptor by binding [3H]-LVP to dog renal medullary preparation.More data for this Ligand-Target Pair
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories
Curated by ChEMBL
Smith Kline & French Laboratories
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Binding affinity of compound towards Vasopressin receptor by binding [3H]-LVP to dog renal medullary preparation.More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories
Curated by ChEMBL
Smith Kline And French Laboratories
Curated by ChEMBL
Affinity DataKi: 0.940nMAssay Description:The compound was tested for the ability to displace opioid receptor kappa specific radioligand [3H]DADLEMore data for this Ligand-Target Pair
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories
Curated by ChEMBL
Smith Kline & French Laboratories
Curated by ChEMBL
Affinity DataKi: 0.990nMAssay Description:Binding affinity of compound towards Vasopressin receptor by binding [3H]-LVP to dog renal medullary preparation.More data for this Ligand-Target Pair
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories
Curated by ChEMBL
Smith Kline & French Laboratories
Curated by ChEMBL
Affinity DataKi: 0.990nMAssay Description:Binding affinity of compound towards Vasopressin receptor by binding [3H]-LVP to dog renal medullary preparation.More data for this Ligand-Target Pair
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories
Curated by ChEMBL
Smith Kline & French Laboratories
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Binding affinity of compound towards Vasopressin receptor by binding [3H]-LVP to dog renal medullary preparation.More data for this Ligand-Target Pair
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories
Curated by ChEMBL
Smith Kline & French Laboratories
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Binding affinity of compound towards Vasopressin receptor by binding [3H]-LVP to dog renal medullary preparation.More data for this Ligand-Target Pair
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories
Curated by ChEMBL
Smith Kline & French Laboratories
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Binding affinity of compound towards Vasopressin receptor by binding [3H]-LVP to dog renal medullary preparation.More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of LVP stimulated adenylate cyclase activity in pig kidney medullary membraneMore data for this Ligand-Target Pair
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories
Curated by ChEMBL
Smith Kline & French Laboratories
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase (Vasopressin V2 receptor) of medullary membranes of human kidneyMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories
Curated by ChEMBL
Smith Kline And French Laboratories
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:The compound was tested for the ability to displace opioid receptor kappa specific radioligand [3H]DADLEMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories
Curated by ChEMBL
Smith Kline And French Laboratories
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:The compound was tested for the ability to displace delta-receptor specific radioligand [3H]DSLETMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories
Curated by ChEMBL
Smith Kline And French Laboratories
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:The compound was tested for the ability to displace opioid receptor delta specific radioligand [3H]-DSLETMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of LVP stimulated adenylate cyclase activity in pig kidney medullary membraneMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories
Curated by ChEMBL
Smith Kline And French Laboratories
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:The compound was tested for the ability to displace delta-receptor specific radioligand [3H]DSLETMore data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Inhibition of LVP stimulated adenylate cyclase activity in pig kidney medullary membraneMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney (Vasopressin V2 receptor)More data for this Ligand-Target Pair
Affinity DataKi: 3.16nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic acetylcholine M2 receptor expressed in CHO cells coexpressed with Gqi5 by scintillatio...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories
Curated by ChEMBL
Smith Kline And French Laboratories
Curated by ChEMBL
Affinity DataKi: 3.30nMAssay Description:The compound was tested for the ability to displace delta-receptor specific radioligand [3H]DSLETMore data for this Ligand-Target Pair
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories
Curated by ChEMBL
Smith Kline & French Laboratories
Curated by ChEMBL
Affinity DataKi: 3.30nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of human kidneyMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories
Curated by ChEMBL
Smith Kline And French Laboratories
Curated by ChEMBL
Affinity DataKi: 3.5nMAssay Description:The compound was tested for the ability to displace opioid receptor kappa specific radioligand [3H]DADLEMore data for this Ligand-Target Pair
Affinity DataKi: 3.60nMAssay Description:In vitro antagonist activity of the compound was measured by inhibition of vasopressin-stimulated adenylate cyclase in renal medullary preparation in...More data for this Ligand-Target Pair
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories
Curated by ChEMBL
Smith Kline & French Laboratories
Curated by ChEMBL
Affinity DataKi: 3.70nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of human kidneyMore data for this Ligand-Target Pair
Affinity DataKi: 3.90nMAssay Description:Compound was tested for inhibition against V2 vasopressin receptor in pig renal medullary membrane preparations.More data for this Ligand-Target Pair
Affinity DataKi: 3.90nMAssay Description:Inhibition of LVP stimulated adenylate cyclase activity in pig kidney medullary membraneMore data for this Ligand-Target Pair
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories
Curated by ChEMBL
Smith Kline & French Laboratories
Curated by ChEMBL
Affinity DataKi: 4.20nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of human kidneyMore data for this Ligand-Target Pair
Affinity DataKi: 4.20nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidneyMore data for this Ligand-Target Pair
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories
Curated by ChEMBL
Smith Kline & French Laboratories
Curated by ChEMBL
Affinity DataKi: 4.40nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of human kidneyMore data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidneyMore data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Tested for inhibition of [3H]-LVP binding to vasopressin receptor in medullary membranes of pig kidney.More data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Compound was tested for inhibition of hog kidney reninMore data for this Ligand-Target Pair
Affinity DataKi: 4.70nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidneyMore data for this Ligand-Target Pair
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories
Curated by ChEMBL
Smith Kline & French Laboratories
Curated by ChEMBL
Affinity DataKi: 4.80nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of human kidneyMore data for this Ligand-Target Pair
Affinity DataKi: 5.30nMAssay Description:Compound was tested for inhibition against V2 vasopressin receptor in pig renal medullary membrane preparations.More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories
Curated by ChEMBL
Smith Kline And French Laboratories
Curated by ChEMBL
Affinity DataKi: 5.40nMAssay Description:The compound was tested for the ability to displace opioid receptor kappa specific radioligand [3H]DADLEMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories
Curated by ChEMBL
Smith Kline And French Laboratories
Curated by ChEMBL
Affinity DataKi: 5.40nMAssay Description:The compound was tested for the ability to displace opioid receptor kappa specific radioligand [3H]DADLEMore data for this Ligand-Target Pair
Affinity DataKi: 5.80nMAssay Description:Tested for inhibition of vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney.More data for this Ligand-Target Pair
Affinity DataKi: 5.80nMAssay Description:Inhibition of LVP stimulated adenylate cyclase activity in pig kidney medullary membraneMore data for this Ligand-Target Pair
Affinity DataKi: 5.80nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidneyMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidneyMore data for this Ligand-Target Pair
Affinity DataKi: 6.20nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.40nMAssay Description:Inhibition of LVP stimulated adenylate cyclase activity in pig kidney medullary membraneMore data for this Ligand-Target Pair
Affinity DataKi: 6.40nMAssay Description:Tested for inhibition of vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney.More data for this Ligand-Target Pair
Affinity DataKi: 6.40nMAssay Description:Compound was tested for inhibition against V2 vasopressin receptor in pig renal medullary membrane preparations.More data for this Ligand-Target Pair
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories
Curated by ChEMBL
Smith Kline & French Laboratories
Curated by ChEMBL
Affinity DataKi: 6.60nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase (Vasopressin V2 receptor) of medullary membranes of human kidneyMore data for this Ligand-Target Pair
Affinity DataKi: 6.80nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney (Vasopressin V2 receptor)More data for this Ligand-Target Pair
Affinity DataKi: 7.60nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidneyMore data for this Ligand-Target Pair