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Found 572 with Last Name = 'morris' and Initial = 'jj'
TargetCathepsin K(Canis familiaris)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50395256(CHEMBL2163587)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of dog recombinant CatK assessed as suppression of enzyme-mediated Z-Phe-Arg-AMC cleavage by QFRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50395235(CHEMBL2164670)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant CatK assessed as suppression of enzyme-mediated Z-Phe-Arg-AMC cleavage incubated for 1 hrs by QFRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50395254(CHEMBL2164682)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant CatK assessed as suppression of enzyme-mediated Z-Phe-Arg-AMC cleavage incubated for 1 hrs by QFRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50395236(CHEMBL2163360)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant CatK assessed as suppression of enzyme-mediated Z-Phe-Arg-AMC cleavage incubated for 1 hrs by QFRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM256830(US10654855, Example 6 | US11236095, Example 6 | US...)
Affinity DataIC50:  1.20nMpH: 7.5 T: 2°CAssay Description:This assay detects inhibitors of AKT1 (PKBα) kinase activity using Caliper LabChip LC3000. The Caliper off-chip incubation mobility shift assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM256830(US10654855, Example 6 | US11236095, Example 6 | US...)
Affinity DataIC50:  1.20nMAssay Description:For Echo dosing the solvent was 100% DMSO. A master plate was prepared with 40 ul of 10 mM stock from our Primary Liquid Store in quadrant 1 of a Lab...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM256830(US10654855, Example 6 | US11236095, Example 6 | US...)
Affinity DataIC50:  1.20nMAssay Description:Following addition of compound or control to the assay plate, 6p1 peptide mix containing 3 μM substrate (5-FAM-GRPRTSSFAEG-CONH2; CRB) and 40 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM256843(US10654855, Example 23 | US11236095, Example 23 | ...)
Affinity DataIC50:  1.30nMAssay Description:For Echo dosing the solvent was 100% DMSO. A master plate was prepared with 40 ul of 10 mM stock from our Primary Liquid Store in quadrant 1 of a Lab...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM256843(US10654855, Example 23 | US11236095, Example 23 | ...)
Affinity DataIC50:  1.30nMpH: 7.5 T: 2°CAssay Description:This assay detects inhibitors of AKT1 (PKBα) kinase activity using Caliper LabChip LC3000. The Caliper off-chip incubation mobility shift assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM256843(US10654855, Example 23 | US11236095, Example 23 | ...)
Affinity DataIC50:  1.30nMAssay Description:Following addition of compound or control to the assay plate, 6p1 peptide mix containing 3 μM substrate (5-FAM-GRPRTSSFAEG-CONH2; CRB) and 40 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM50427336(CHEMBL2325992 | US10654855, Example 11 | US1123609...)
Affinity DataIC50:  2nMAssay Description:For Echo dosing the solvent was 100% DMSO. A master plate was prepared with 40 ul of 10 mM stock from our Primary Liquid Store in quadrant 1 of a Lab...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM50427336(CHEMBL2325992 | US10654855, Example 11 | US1123609...)
Affinity DataIC50:  2nMAssay Description:Following addition of compound or control to the assay plate, 6p1 peptide mix containing 3 μM substrate (5-FAM-GRPRTSSFAEG-CONH2; CRB) and 40 &#...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin K(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50395228(CHEMBL2164674)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant CatK assessed as suppression of enzyme-mediated Z-Phe-Arg-AMC cleavage incubated for 1 hrs by QFRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50395244(CHEMBL2163582)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant CatK assessed as suppression of enzyme-mediated Z-Phe-Arg-AMC cleavage incubated for 1 hrs by QFRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM50427336(CHEMBL2325992 | US10654855, Example 11 | US1123609...)
Affinity DataIC50:  2nMpH: 7.5 T: 2°CAssay Description:This assay detects inhibitors of AKT1 (PKBα) kinase activity using Caliper LabChip LC3000. The Caliper off-chip incubation mobility shift assay...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin K(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50395241(CHEMBL2163585)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant CatK assessed as suppression of enzyme-mediated Z-Phe-Arg-AMC cleavage incubated for 1 hrs by QFRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50395238(CHEMBL2163589)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant CatK assessed as suppression of enzyme-mediated Z-Phe-Arg-AMC cleavage incubated for 1 hrs by QFRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM256844(US10654855, Example 24 | US11236095, Example 24 | ...)
Affinity DataIC50:  2.20nMAssay Description:Following addition of compound or control to the assay plate, 6p1 peptide mix containing 3 μM substrate (5-FAM-GRPRTSSFAEG-CONH2; CRB) and 40 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM256844(US10654855, Example 24 | US11236095, Example 24 | ...)
Affinity DataIC50:  2.20nMAssay Description:For Echo dosing the solvent was 100% DMSO. A master plate was prepared with 40 ul of 10 mM stock from our Primary Liquid Store in quadrant 1 of a Lab...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM256844(US10654855, Example 24 | US11236095, Example 24 | ...)
Affinity DataIC50:  2.20nMpH: 7.5 T: 2°CAssay Description:This assay detects inhibitors of AKT1 (PKBα) kinase activity using Caliper LabChip LC3000. The Caliper off-chip incubation mobility shift assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM256828(US10654855, Example 3A | US11236095, Example 3A | ...)
Affinity DataIC50:  2.60nMpH: 7.5 T: 2°CAssay Description:This assay detects inhibitors of AKT1 (PKBα) kinase activity using Caliper LabChip LC3000. The Caliper off-chip incubation mobility shift assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM256828(US10654855, Example 3A | US11236095, Example 3A | ...)
Affinity DataIC50:  2.60nMAssay Description:For Echo dosing the solvent was 100% DMSO. A master plate was prepared with 40 ul of 10 mM stock from our Primary Liquid Store in quadrant 1 of a Lab...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM256828(US10654855, Example 3A | US11236095, Example 3A | ...)
Affinity DataIC50:  2.60nMAssay Description:Following addition of compound or control to the assay plate, 6p1 peptide mix containing 3 μM substrate (5-FAM-GRPRTSSFAEG-CONH2; CRB) and 40 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM256833(US10654855, Example 12 | US11236095, Example 12 | ...)
Affinity DataIC50:  2.70nMpH: 7.5 T: 2°CAssay Description:This assay detects inhibitors of AKT1 (PKBα) kinase activity using Caliper LabChip LC3000. The Caliper off-chip incubation mobility shift assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM256833(US10654855, Example 12 | US11236095, Example 12 | ...)
Affinity DataIC50:  2.70nMAssay Description:Following addition of compound or control to the assay plate, 6p1 peptide mix containing 3 μM substrate (5-FAM-GRPRTSSFAEG-CONH2; CRB) and 40 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM256833(US10654855, Example 12 | US11236095, Example 12 | ...)
Affinity DataIC50:  2.70nMAssay Description:For Echo dosing the solvent was 100% DMSO. A master plate was prepared with 40 ul of 10 mM stock from our Primary Liquid Store in quadrant 1 of a Lab...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM50427361(CHEMBL2325727 | US10654855, Example 11A | US112360...)
Affinity DataIC50:  2.80nMAssay Description:For Echo dosing the solvent was 100% DMSO. A master plate was prepared with 40 ul of 10 mM stock from our Primary Liquid Store in quadrant 1 of a Lab...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM256875(US11236095, Example 11A | US9492453, 11B)
Affinity DataIC50:  2.80nMAssay Description:Following addition of compound or control to the assay plate, 6p1 peptide mix containing 3 μM substrate (5-FAM-GRPRTSSFAEG-CONH2; CRB) and 40 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM50427361(CHEMBL2325727 | US10654855, Example 11A | US112360...)
Affinity DataIC50:  2.80nMpH: 7.5 T: 2°CAssay Description:This assay detects inhibitors of AKT1 (PKBα) kinase activity using Caliper LabChip LC3000. The Caliper off-chip incubation mobility shift assay...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM50427335(CHEMBL2325993 | US10654855, Example 25 | US1123609...)
Affinity DataIC50:  2.90nMAssay Description:For Echo dosing the solvent was 100% DMSO. A master plate was prepared with 40 ul of 10 mM stock from our Primary Liquid Store in quadrant 1 of a Lab...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM50427335(CHEMBL2325993 | US10654855, Example 25 | US1123609...)
Affinity DataIC50:  2.90nMpH: 7.5 T: 2°CAssay Description:This assay detects inhibitors of AKT1 (PKBα) kinase activity using Caliper LabChip LC3000. The Caliper off-chip incubation mobility shift assay...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM50427335(CHEMBL2325993 | US10654855, Example 25 | US1123609...)
Affinity DataIC50:  2.90nMAssay Description:Following addition of compound or control to the assay plate, 6p1 peptide mix containing 3 μM substrate (5-FAM-GRPRTSSFAEG-CONH2; CRB) and 40 &#...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM256835(US10654855, Example 14 | US11236095, Example 14 | ...)
Affinity DataIC50:  3nMAssay Description:Following addition of compound or control to the assay plate, 6p1 peptide mix containing 3 μM substrate (5-FAM-GRPRTSSFAEG-CONH2; CRB) and 40 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCathepsin K(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50395234(CHEMBL2164669)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant CatK assessed as suppression of enzyme-mediated Z-Phe-Arg-AMC cleavage incubated for 1 hrs by QFRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50395243(CHEMBL2163583)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant CatK assessed as suppression of enzyme-mediated Z-Phe-Arg-AMC cleavage incubated for 1 hrs by QFRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50395250(CHEMBL2164687)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant CatK assessed as suppression of enzyme-mediated Z-Phe-Arg-AMC cleavage incubated for 1 hrs by QFRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50395251(CHEMBL2164686)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant CatK assessed as suppression of enzyme-mediated Z-Phe-Arg-AMC cleavage incubated for 1 hrs by QFRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM256835(US10654855, Example 14 | US11236095, Example 14 | ...)
Affinity DataIC50:  3nMAssay Description:For Echo dosing the solvent was 100% DMSO. A master plate was prepared with 40 ul of 10 mM stock from our Primary Liquid Store in quadrant 1 of a Lab...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM256835(US10654855, Example 14 | US11236095, Example 14 | ...)
Affinity DataIC50:  3nMpH: 7.5 T: 2°CAssay Description:This assay detects inhibitors of AKT1 (PKBα) kinase activity using Caliper LabChip LC3000. The Caliper off-chip incubation mobility shift assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCathepsin K(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50397138(CHEMBL2172003)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant cathepsin-k using Z-Phe-Arg-AMC as substrate preincubated for 15 mins measured after 1 hr by QFRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM443385(ALTERNATIVE ROUTE 1: (S)-4-AMINO-N-(1-(4-CHLOROPHE...)
Affinity DataIC50:  3.20nMAssay Description:Following addition of compound or control to the assay plate, 6p1 peptide mix containing 3 μM substrate (5-FAM-GRPRTSSFAEG-CONH2; CRB) and 40 &#...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM443385(ALTERNATIVE ROUTE 1: (S)-4-AMINO-N-(1-(4-CHLOROPHE...)
Affinity DataIC50:  3.20nMAssay Description:For Echo dosing the solvent was 100% DMSO. A master plate was prepared with 40 ul of 10 mM stock from our Primary Liquid Store in quadrant 1 of a Lab...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM256836(BDBM50427349 | US10654855, Example 15 | US11236095...)
Affinity DataIC50:  3.20nMpH: 7.5 T: 2°CAssay Description:This assay detects inhibitors of AKT1 (PKBα) kinase activity using Caliper LabChip LC3000. The Caliper off-chip incubation mobility shift assay...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM256876(US11236095, Example 49A | US9492453, 49B)
Affinity DataIC50:  3.30nMAssay Description:Following addition of compound or control to the assay plate, 6p1 peptide mix containing 3 μM substrate (5-FAM-GRPRTSSFAEG-CONH2; CRB) and 40 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM256861(US10654855, Example 49A | US11236095, Example 49B ...)
Affinity DataIC50:  3.30nMpH: 7.5 T: 2°CAssay Description:This assay detects inhibitors of AKT1 (PKBα) kinase activity using Caliper LabChip LC3000. The Caliper off-chip incubation mobility shift assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM256861(US10654855, Example 49A | US11236095, Example 49B ...)
Affinity DataIC50:  3.30nMAssay Description:For Echo dosing the solvent was 100% DMSO. A master plate was prepared with 40 ul of 10 mM stock from our Primary Liquid Store in quadrant 1 of a Lab...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM256865(US10654855, Example 54 | US11236095, Example 54 | ...)
Affinity DataIC50:  3.40nMpH: 7.5 T: 2°CAssay Description:This assay detects inhibitors of AKT1 (PKBα) kinase activity using Caliper LabChip LC3000. The Caliper off-chip incubation mobility shift assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM256865(US10654855, Example 54 | US11236095, Example 54 | ...)
Affinity DataIC50:  3.40nMAssay Description:Following addition of compound or control to the assay plate, 6p1 peptide mix containing 3 μM substrate (5-FAM-GRPRTSSFAEG-CONH2; CRB) and 40 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM256865(US10654855, Example 54 | US11236095, Example 54 | ...)
Affinity DataIC50:  3.40nMAssay Description:For Echo dosing the solvent was 100% DMSO. A master plate was prepared with 40 ul of 10 mM stock from our Primary Liquid Store in quadrant 1 of a Lab...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM50427334(CHEMBL2325994 | US10654855, Example 47 | US1123609...)
Affinity DataIC50:  3.60nMpH: 7.5 T: 2°CAssay Description:This assay detects inhibitors of AKT1 (PKBα) kinase activity using Caliper LabChip LC3000. The Caliper off-chip incubation mobility shift assay...More data for this Ligand-Target Pair
In DepthDetails US Patent
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