TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of wild type human recombinant LRRK2 expressed in baculovirus using fluorescein-ERM as substrate preincubated for 30 mins followed by subs...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataIC50: 728nMAssay Description:Inhibition of wild type human recombinant LRRK2 expressed in baculovirus using fluorescein-ERM as substrate preincubated for 30 mins followed by subs...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
Affinity DataEC50: 1.56E+5nMAssay Description:Inhibition of GluR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+6nMAssay Description:Inhibition of GluR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 2.10E+4nMAssay Description:Inhibition of GluR1 expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.96E+4nMAssay Description:Inhibition of GluR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.98E+6nMAssay Description:Inhibition of GluR2 flop expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.20E+3nMAssay Description:Inhibition of GluR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 4.50E+3nMAssay Description:Inhibition of GluR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 290nMAssay Description:Inhibition of GluR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 150nMAssay Description:Inhibition of GluR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 870nMAssay Description:Inhibition of rat recombinant GluR4 in cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 910nMAssay Description:Inhibition of GluR1 expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 2.88E+3nMAssay Description:Inhibition of GluR1 expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 660nMAssay Description:Inhibition of GluR1 expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 520nMAssay Description:Inhibition of GluR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 520nMAssay Description:Inhibition of GluR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 230nMAssay Description:Inhibition of GluR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.60E+3nMAssay Description:Inhibition of human recombinant GluR2More data for this Ligand-Target Pair
Affinity DataEC50: 2.50E+3nMAssay Description:Inhibition of human recombinant GluR2More data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+4nMAssay Description:Inhibition of human recombinant GluR2More data for this Ligand-Target Pair
Affinity DataEC50: 150nMAssay Description:Agonist activity at GluR2 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 1.66E+3nMAssay Description:Inhibition of GluR3 expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 5.65E+3nMAssay Description:Inhibition of GluR1 expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.44E+3nMAssay Description:Inhibition of GluR2 flop expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 520nMAssay Description:Agonist activity at GluR2 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 520nMAssay Description:Agonist activity at GluR2 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 794nMAssay Description:Modulatory activity at GluA2 receptor LBDMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Modulatory activity at GluA2 receptor LBDMore data for this Ligand-Target Pair
Affinity DataEC50: 398nMAssay Description:Modulatory activity at GluA2 receptor LBDMore data for this Ligand-Target Pair
Affinity DataEC50: 5.01E+3nMAssay Description:Modulatory activity at GluA2 receptor LBDMore data for this Ligand-Target Pair
Affinity DataEC50: 2.51E+3nMAssay Description:Modulatory activity at GluA2 receptor LBDMore data for this Ligand-Target Pair
Affinity DataEC50: 2.51E+3nMAssay Description:Modulatory activity at GluA2 receptor LBDMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Modulatory activity at GluA2 receptor LBDMore data for this Ligand-Target Pair
Affinity DataEC50: 398nMAssay Description:Modulatory activity at GluA2 receptor LBDMore data for this Ligand-Target Pair
Affinity DataEC50: 7.94E+3nMAssay Description:Modulatory activity at GluA2 receptor LBDMore data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Modulatory activity at GluA2 receptor LBDMore data for this Ligand-Target Pair
Affinity DataEC50: 158nMAssay Description:Modulatory activity at GluA2 receptor LBDMore data for this Ligand-Target Pair
Affinity DataEC50: 501nMAssay Description:Modulatory activity at GluA2 receptor LBDMore data for this Ligand-Target Pair
Affinity DataEC50: 2.00E+3nMAssay Description:Modulatory activity at GluA2 receptor LBDMore data for this Ligand-Target Pair
Affinity DataEC50: 1.26E+3nMAssay Description:Modulatory activity at GluA2 receptor LBDMore data for this Ligand-Target Pair
Affinity DataEC50: 398nMAssay Description:Modulatory activity at GluA2 receptor LBDMore data for this Ligand-Target Pair
Affinity DataEC50: >3.16E+4nMAssay Description:Modulatory activity at GluA2 receptor LBDMore data for this Ligand-Target Pair
Affinity DataEC50: 501nMAssay Description:Modulatory activity at GluA2 receptor LBDMore data for this Ligand-Target Pair
Affinity DataEC50: 1.26E+3nMAssay Description:Modulatory activity at GluA2 receptor LBDMore data for this Ligand-Target Pair
Affinity DataEC50: 1.26E+3nMAssay Description:Modulatory activity at GluA2 receptor LBDMore data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Modulatory activity at GluA2 receptor LBDMore data for this Ligand-Target Pair