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Found 69 with Last Name = 'moseley' and Initial = 'am'
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038171(7-Chloro-4-hydroxy-3-[3-(thiophen-3-yloxy)-phenyl]...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of the binding of [3H]-L-689,560 ([3H]-4) to the strychnine-insensitive glycine site on rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038168(7-Chloro-4-hydroxy-3-(3-phenoxy-phenyl)-1H-quinoli...)
Affinity DataIC50:  2nMAssay Description:Inhibition of the binding of [3H]-L-689,560 ([3H]-4) to the strychnine-insensitive glycine site on rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50041466(7-Chloro-4-hydroxy-3-[3-(4-methoxymethoxy-benzyl)-...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of the binding of [3H]-L-689,560 ([3H]-4) to the strychnine-insensitive glycine site on rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50041468(7-Chloro-4-hydroxy-3-(3-thiophen-3-ylmethyl-phenyl...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of the binding of [3H]-L-689,560 ([3H]-4) to the strychnine-insensitive glycine site on rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005075((2R,4S)-5,7-Dichloro-4-(3-phenyl-ureido)-1,2,3,4-t...)
Affinity DataIC50:  4nMAssay Description:Inhibition of the binding of [3H]-L-689,560 ([3H]-4) to the strychnine-insensitive glycine site on rat brain membranesMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50041464(3-(3-Benzyl-phenyl)-7-chloro-4-hydroxy-1H-quinolin...)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of the binding of [3H]-L-689,560 ([3H]-4) to the strychnine-insensitive glycine site on rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50041465(7-Chloro-4-hydroxy-3-[3-(4-methoxy-benzyl)-phenyl]...)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of the binding of [3H]-L-689,560 ([3H]-4) to the strychnine-insensitive glycine site on rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005072(5,7-Dichloro-4-(3-p-tolyl-ureido)-1,2,3,4-tetrahyd...)
Affinity DataIC50:  5nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005044((2R,4S)-5,7-Dichloro-4-(2-oxo-3-phenyl-imidazolidi...)
Affinity DataIC50:  6nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005055(7-Chloro-5-iodo-4-(3-phenyl-ureido)-1,2,3,4-tetrah...)
Affinity DataIC50:  6nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005086(5,7-Dichloro-4-(3-o-tolyl-ureido)-1,2,3,4-tetrahyd...)
Affinity DataIC50:  7.30nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005075((2R,4S)-5,7-Dichloro-4-(3-phenyl-ureido)-1,2,3,4-t...)
Affinity DataIC50:  7.40nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005047(7-Chloro-5-iodo-4-phenylacetylamino-1,2,3,4-tetrah...)
Affinity DataIC50:  10nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005081(5,7-Dichloro-4-(3-naphthalen-1-yl-ureido)-1,2,3,4-...)
Affinity DataIC50:  11nMAssay Description:Inhibition of [3H]- glycine binding to N-methyl-D-aspartate glutamate receptor from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005053((-) 5,7-Dichloro-4-phenylacetylamino-1,2,3,4-tetra...)
Affinity DataIC50:  11nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005053((-) 5,7-Dichloro-4-phenylacetylamino-1,2,3,4-tetra...)
Affinity DataIC50:  11nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005053((-) 5,7-Dichloro-4-phenylacetylamino-1,2,3,4-tetra...)
Affinity DataIC50:  14nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005034(7-Chloro-5-iodo-4-oxo-1,4-dihydro-quinoline-2-carb...)
Affinity DataIC50:  14nMAssay Description:Inhibition of the binding of [3H]-L-689,560 ([3H]-4) to the strychnine-insensitive glycine site on rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005038(5,7-Dichloro-4-(3-m-tolyl-ureido)-1,2,3,4-tetrahyd...)
Affinity DataIC50:  18nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005080(4-[2-(4-Amino-phenyl)-acetylamino]-5,7-dichloro-1,...)
Affinity DataIC50:  18nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005054(5,7-Dichloro-4-(3,3-diphenyl-ureido)-1,2,3,4-tetra...)
Affinity DataIC50:  19nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005087(5,7-Dichloro-4-[(9H-fluorene-9-carbonyl)-amino]-1,...)
Affinity DataIC50:  25nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005039(5,7-Dichloro-4-(1-oxo-1,3-dihydro-isoindol-2-yl)-1...)
Affinity DataIC50:  27nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005074(5,7-Dichloro-4-(3-cyclohexyl-ureido)-1,2,3,4-tetra...)
Affinity DataIC50:  28nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005069(5,7-Dichloro-4-(2-thiophen-3-yl-acetylamino)-1,2,3...)
Affinity DataIC50:  30nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005067(5,7-Dichloro-4-[2-(4-hydroxy-phenyl)-acetylamino]-...)
Affinity DataIC50:  30nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005035((2R,4R)-5,7-Dichloro-4-phenylcarbamoylmethyl-1,2,3...)
Affinity DataIC50:  30nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005064(4-(3-Benzyl-ureido)-5,7-dichloro-1,2,3,4-tetrahydr...)
Affinity DataIC50:  30nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005084(5,7-Dichloro-4-(2-thiophen-2-yl-acetylamino)-1,2,3...)
Affinity DataIC50:  32nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005036(5,7-Dichloro-4-(2-p-tolyl-acetylamino)-1,2,3,4-tet...)
Affinity DataIC50:  34nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005062(5,7-Dichloro-4-[2-(4-methoxy-phenyl)-acetylamino]-...)
Affinity DataIC50:  39nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005057(5-Chloro-7-iodo-4-phenylacetylamino-1,2,3,4-tetrah...)
Affinity DataIC50:  42nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005059(5,7-Dichloro-4-(3-methyl-3-phenyl-ureido)-1,2,3,4-...)
Affinity DataIC50:  45nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005056(5,7-Dichloro-4-(2-oxo-pyrrolidin-1-yl)-1,2,3,4-tet...)
Affinity DataIC50:  46nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005066(5,7-Dichloro-4-[2-(4-chloro-phenyl)-acetylamino]-1...)
Affinity DataIC50:  52nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005046(5,7-Dichloro-4-diphenylacetylamino-1,2,3,4-tetrahy...)
Affinity DataIC50:  61nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005051(5,7-Dimethyl-4-phenylacetylamino-1,2,3,4-tetrahydr...)
Affinity DataIC50:  67nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50004952(3-(2-Carboxy-ethyl)-4,6-dichloro-1H-indole-2-carbo...)
Affinity DataIC50:  69nMAssay Description:Inhibition of the binding of [3H]-L-689,560 ([3H]-4) to the strychnine-insensitive glycine site on rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005043(5,7-Dichloro-4-(3-oxo-3,4-dihydro-1H-isoquinolin-2...)
Affinity DataIC50:  72nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005065(5,7-Dichloro-4-(3-phenyl-propionylamino)-1,2,3,4-t...)
Affinity DataIC50:  76nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005078(4-Benzyloxycarbonylamino-5,7-dichloro-1,2,3,4-tetr...)
Affinity DataIC50:  79nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005063(5,7-Dichloro-4-(3-phenyl-thioureido)-1,2,3,4-tetra...)
Affinity DataIC50:  90nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005049(4-Benzoylamino-5,7-dichloro-1,2,3,4-tetrahydro-qui...)
Affinity DataIC50:  100nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005040(5,7-Dichloro-4-(2-cyclohexyl-acetylamino)-1,2,3,4-...)
Affinity DataIC50:  110nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005079(5,7-Dichloro-4-[(furan-2-carbonyl)-amino]-1,2,3,4-...)
Affinity DataIC50:  150nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005058(5,7-Dichloro-4-(cyclohexanecarbonyl-amino)-1,2,3,4...)
Affinity DataIC50:  170nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005045(5,7-Dichloro-4-(4-phenyl-butyrylamino)-1,2,3,4-tet...)
Affinity DataIC50:  170nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50041467(7-Chloro-4-hydroxy-3-phenyl-1H-quinolin-2-one | 7-...)
Affinity DataIC50:  170nMAssay Description:Inhibition of the binding of [3H]-L-689,560 ([3H]-4) to the strychnine-insensitive glycine site on rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005048(5,7-Dichloro-4-[(2,3-dihydro-indole-1-carbonyl)-am...)
Affinity DataIC50:  220nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005077(4-Butyrylamino-5,7-dichloro-1,2,3,4-tetrahydro-qui...)
Affinity DataIC50:  370nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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