TargetNeuromedin-K receptor(Homo sapiens (Human))
Neuroscience Cedd Glaxosmithkline Research & Development
Curated by ChEMBL
Neuroscience Cedd Glaxosmithkline Research & Development
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Binding affinity to NK3 receptorMore data for this Ligand-Target Pair
TargetNeuromedin-K receptor(Homo sapiens (Human))
Neuroscience Cedd Glaxosmithkline Research & Development
Curated by ChEMBL
Neuroscience Cedd Glaxosmithkline Research & Development
Curated by ChEMBL
Affinity DataKi: 1.26nMAssay Description:Binding affinity to NK3 receptorMore data for this Ligand-Target Pair
TargetNeuromedin-K receptor(Homo sapiens (Human))
Neuroscience Cedd Glaxosmithkline Research & Development
Curated by ChEMBL
Neuroscience Cedd Glaxosmithkline Research & Development
Curated by ChEMBL
Affinity DataKi: 1.26nMAssay Description:Binding affinity to NK3 receptorMore data for this Ligand-Target Pair
TargetNeuromedin-K receptor(Homo sapiens (Human))
Neuroscience Cedd Glaxosmithkline Research & Development
Curated by ChEMBL
Neuroscience Cedd Glaxosmithkline Research & Development
Curated by ChEMBL
Affinity DataKi: 1.58nMAssay Description:Binding affinity to NK3 receptorMore data for this Ligand-Target Pair
TargetNeuromedin-K receptor(Homo sapiens (Human))
Neuroscience Cedd Glaxosmithkline Research & Development
Curated by ChEMBL
Neuroscience Cedd Glaxosmithkline Research & Development
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Binding affinity to NK3 receptorMore data for this Ligand-Target Pair
TargetNeuromedin-K receptor(Homo sapiens (Human))
Neuroscience Cedd Glaxosmithkline Research & Development
Curated by ChEMBL
Neuroscience Cedd Glaxosmithkline Research & Development
Curated by ChEMBL
Affinity DataKi: 3.16nMAssay Description:Binding affinity to NK3 receptorMore data for this Ligand-Target Pair
TargetNeuromedin-K receptor(Homo sapiens (Human))
Neuroscience Cedd Glaxosmithkline Research & Development
Curated by ChEMBL
Neuroscience Cedd Glaxosmithkline Research & Development
Curated by ChEMBL
Affinity DataKi: 3.98nMAssay Description:Binding affinity to NK3 receptorMore data for this Ligand-Target Pair
TargetNeuromedin-K receptor(Homo sapiens (Human))
Neuroscience Cedd Glaxosmithkline Research & Development
Curated by ChEMBL
Neuroscience Cedd Glaxosmithkline Research & Development
Curated by ChEMBL
Affinity DataKi: 5.01nMAssay Description:Binding affinity to NK3 receptorMore data for this Ligand-Target Pair
TargetNeuromedin-K receptor(Homo sapiens (Human))
Neuroscience Cedd Glaxosmithkline Research & Development
Curated by ChEMBL
Neuroscience Cedd Glaxosmithkline Research & Development
Curated by ChEMBL
Affinity DataKi: 5.01nMAssay Description:Binding affinity to NK3 receptorMore data for this Ligand-Target Pair
TargetNeuromedin-K receptor(Homo sapiens (Human))
Neuroscience Cedd Glaxosmithkline Research & Development
Curated by ChEMBL
Neuroscience Cedd Glaxosmithkline Research & Development
Curated by ChEMBL
Affinity DataKi: 6.31nMAssay Description:Binding affinity to NK3 receptorMore data for this Ligand-Target Pair
TargetNeuromedin-K receptor(Homo sapiens (Human))
Neuroscience Cedd Glaxosmithkline Research & Development
Curated by ChEMBL
Neuroscience Cedd Glaxosmithkline Research & Development
Curated by ChEMBL
Affinity DataKi: 6.31nMAssay Description:Binding affinity to NK3 receptorMore data for this Ligand-Target Pair
TargetNeuromedin-K receptor(Homo sapiens (Human))
Neuroscience Cedd Glaxosmithkline Research & Development
Curated by ChEMBL
Neuroscience Cedd Glaxosmithkline Research & Development
Curated by ChEMBL
Affinity DataKi: 7.94nMAssay Description:Binding affinity to NK3 receptorMore data for this Ligand-Target Pair
TargetNeuromedin-K receptor(Homo sapiens (Human))
Neuroscience Cedd Glaxosmithkline Research & Development
Curated by ChEMBL
Neuroscience Cedd Glaxosmithkline Research & Development
Curated by ChEMBL
Affinity DataKi: 7.94nMAssay Description:Binding affinity to NK3 receptorMore data for this Ligand-Target Pair
TargetNeuromedin-K receptor(Homo sapiens (Human))
Neuroscience Cedd Glaxosmithkline Research & Development
Curated by ChEMBL
Neuroscience Cedd Glaxosmithkline Research & Development
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Binding affinity to NK3 receptorMore data for this Ligand-Target Pair
TargetNeuromedin-K receptor(Homo sapiens (Human))
Neuroscience Cedd Glaxosmithkline Research & Development
Curated by ChEMBL
Neuroscience Cedd Glaxosmithkline Research & Development
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Binding affinity to NK3 receptorMore data for this Ligand-Target Pair
TargetNeuromedin-K receptor(Homo sapiens (Human))
Neuroscience Cedd Glaxosmithkline Research & Development
Curated by ChEMBL
Neuroscience Cedd Glaxosmithkline Research & Development
Curated by ChEMBL
Affinity DataKi: 15.8nMAssay Description:Binding affinity to NK3 receptorMore data for this Ligand-Target Pair
TargetNeuromedin-K receptor(Homo sapiens (Human))
Neuroscience Cedd Glaxosmithkline Research & Development
Curated by ChEMBL
Neuroscience Cedd Glaxosmithkline Research & Development
Curated by ChEMBL
Affinity DataKi: 251nMAssay Description:Binding affinity to NK3 receptorMore data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.0360nMAssay Description:In vitro inhibitory activity against human neutrophil elastase (HNE)More data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.0470nMAssay Description:In vitro inhibitory activity against human neutrophil elastase (HNE)More data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.450nMAssay Description:In vitro inhibitory activity in human whole blood (HWB) elastase at a concentration of 10More data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.690nMAssay Description:In vitro inhibitory activity against human neutrophil elastase (HNE)More data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:In vitro inhibitory activity against human neutrophil elastase (HNE)More data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Binding affinity for dopamine D4-like receptor labelled with [3H]YM-09151-2 in retinaMore data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:In vitro inhibitory activity against human neutrophil elastase (HNE)More data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:In vitro inhibitory activity in human whole blood (HWB) elastase at a concentration of 10 uMMore data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: >10nMAssay Description:In vitro inhibitory activity in human whole blood (HWB) elastaseMore data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibitory concentration against ElastaseMore data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibitory concentration against ElastaseMore data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:In vitro inhibitory activity against human neutrophil elastase (HNE)More data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:In vitro inhibitory activity against human neutrophil elastase (HNE)More data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 94nMAssay Description:In vitro inhibitory activity against human neutrophil elastase (HNE)More data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibitory concentration against ElastaseMore data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:In vitro inhibitory activity in human whole blood (HWB) elastase at a concentration of 10 uMMore data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 242nMAssay Description:Inhibitory concentration against ElastaseMore data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 274nMAssay Description:Inhibitory concentration against ElastaseMore data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: >500nMAssay Description:In vitro inhibitory activity against human neutrophil elastase (HNE)More data for this Ligand-Target Pair
Affinity DataEC50: 126nMAssay Description:Agonist activity at human muscarinic M4 receptor expressed in CHO cells co-expressing Gqi5 chimaeric G-protein assessed as effect on calcium mobiliza...More data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Agonist activity at human muscarinic M5 receptor expressed in CHO cells assessed as effect on calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as effect on calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 501nMAssay Description:Agonist activity at human muscarinic M2 receptor expressed in CHO cells co-expressing Gqi5 chimaeric G-protein assessed as effect on calcium mobiliza...More data for this Ligand-Target Pair
Affinity DataEC50: 794nMAssay Description:Agonist activity at human muscarinic M3 receptor expressed in CHO cells assessed as effect on calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Agonist activity at human muscarinic M4 receptor expressed in CHO cells co-expressing Gqi5 chimaeric G-protein assessed as effect on calcium mobiliza...More data for this Ligand-Target Pair
Affinity DataEC50: 50.1nMAssay Description:Agonist activity at human muscarinic M5 receptor expressed in CHO cells assessed as effect on calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.26nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as effect on calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 794nMAssay Description:Agonist activity at human muscarinic M2 receptor expressed in CHO cells co-expressing Gqi5 chimaeric G-protein assessed as effect on calcium mobiliza...More data for this Ligand-Target Pair
Affinity DataEC50: 2.00E+3nMAssay Description:Agonist activity at human muscarinic M3 receptor expressed in CHO cells assessed as effect on calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 200nMAssay Description:Agonist activity at human muscarinic M4 receptor expressed in CHO cells co-expressing Gqi5 chimaeric G-protein assessed as effect on calcium mobiliza...More data for this Ligand-Target Pair
Affinity DataEC50: 158nMAssay Description:Agonist activity at human muscarinic M5 receptor expressed in CHO cells assessed as effect on calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.51nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as effect on calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 398nMAssay Description:Agonist activity at human muscarinic M2 receptor expressed in CHO cells co-expressing Gqi5 chimaeric G-protein assessed as effect on calcium mobiliza...More data for this Ligand-Target Pair