Affinity DataKi: 1.40nMAssay Description:Inhibition of recombinant matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Displacement of [125I]AB-MECA from human A3 adenosine receptor expressed in CHO cell membrane incubated for 60 mins by gamma counter methodMore data for this Ligand-Target Pair
Affinity DataKi: 4.90nMAssay Description:Displacement of [125I]-I-AB-MECA from recombinant human adenosine A3 receptor expressed in CHO cells after 60 mins by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 6.10nMAssay Description:Inhibition of recombinant matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
Affinity DataKi: 6.70nMAssay Description:Displacement of [125I]-I-AB-MECA from recombinant human adenosine A3 receptor expressed in CHO cells after 60 mins by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 7.80nMAssay Description:Displacement of [125I]-I-AB-MECA from recombinant human adenosine A3 receptor expressed in CHO cells after 60 mins by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 8.60nMAssay Description:Displacement of [125I]-I-AB-MECA from recombinant human adenosine A3 receptor expressed in CHO cells after 60 mins by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 9.20nMAssay Description:Displacement of [125I]-I-AB-MECA from recombinant human adenosine A3 receptor expressed in CHO cells after 60 mins by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Displacement of [125I]-I-AB-MECA from rat adenosine A3 receptor expressed in RBL-2H3 cells after 60 mins by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Displacement of [125I]-I-AB-MECA from recombinant human adenosine A3 receptor expressed in CHO cells after 60 mins by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Displacement of [125I]-I-AB-MECA from recombinant human adenosine A3 receptor expressed in CHO cells after 60 mins by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Displacement of [125I]-I-AB-MECA from recombinant human adenosine A3 receptor expressed in CHO cells after 60 mins by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition of recombinant matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Displacement of [125I]-I-AB-MECA from rat adenosine A3 receptor expressed in RBL-2H3 cells after 60 mins by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 39nMAssay Description:Displacement of [125I]-I-AB-MECA from rat adenosine A3 receptor expressed in RBL-2H3 cells after 60 mins by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Displacement of [125I]-I-AB-MECA from rat adenosine A3 receptor expressed in RBL-2H3 cells after 60 mins by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 58nMAssay Description:Displacement of [125I]-I-AB-MECA from rat adenosine A3 receptor expressed in RBL-2H3 cells after 60 mins by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 59nMAssay Description:Displacement of [125I]-I-AB-MECA from rat adenosine A3 receptor expressed in RBL-2H3 cells after 60 mins by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 62nMAssay Description:Inhibition of recombinant matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
Affinity DataKi: 65nMAssay Description:Displacement of [125I]-I-AB-MECA from rat adenosine A3 receptor expressed in RBL-2H3 cells after 60 mins by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Displacement of [3H]-CGS21680 from human adenosine A2A receptor expressed in HEK293 cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 160nMAssay Description:Displacement of [125I]-I-AB-MECA from recombinant human adenosine A3 receptor expressed in CHO cells after 60 mins by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 176nMAssay Description:Displacement of [125I]-I-AB-MECA from rat adenosine A3 receptor expressed in RBL-2H3 cells after 60 mins by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 231nMAssay Description:Displacement of [125I]-I-AB-MECA from rat adenosine A3 receptor expressed in RBL-2H3 cells after 60 mins by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 260nMAssay Description:Displacement of [125I]AB-MECA from human A3 adenosine receptor expressed in CHO cell membrane incubated for 60 mins by gamma counter methodMore data for this Ligand-Target Pair
Affinity DataKi: 380nMAssay Description:Displacement of [125I]AB-MECA from human A3 adenosine receptor expressed in CHO cell membrane incubated for 60 mins by gamma counter methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.58E+3nMAssay Description:Displacement of [3H]-R-PIA from recombinant human adenosine A1 receptor expressed in CHO cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.67E+3nMAssay Description:Displacement of [3H]R-PIA from recombinant human A1 adenosine receptor expressed in CHO cell membrane incubated for 60 mins by liquid scintillation c...More data for this Ligand-Target Pair
Affinity DataKi: 1.76E+3nMAssay Description:Displacement of [3H]-CGS21680 from human adenosine A2A receptor expressed in HEK293 cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.17E+3nMAssay Description:Displacement of [3H]-R-PIA from recombinant human adenosine A1 receptor expressed in CHO cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.20E+3nMAssay Description:Displacement of [3H]R-PIA from recombinant human A1 adenosine receptor expressed in CHO cell membrane incubated for 60 mins by liquid scintillation c...More data for this Ligand-Target Pair
Affinity DataKi: 2.20E+3nMAssay Description:Displacement of [3H]-CGS21680 from human adenosine A2A receptor expressed in HEK293 cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.30E+3nMAssay Description:Displacement of [3H]CGS21680 from recombinant human A2A adenosine receptor expressed in HEK293 cells incubated for 60 mins by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 2.39E+3nMAssay Description:Displacement of [3H]CGS21680 from recombinant human A2A adenosine receptor expressed in HEK293 cells incubated for 60 mins by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 2.45E+3nMAssay Description:Displacement of [3H]R-PIA from recombinant human A1 adenosine receptor expressed in CHO cell membrane incubated for 60 mins by liquid scintillation c...More data for this Ligand-Target Pair
Affinity DataKi: 2.53E+3nMAssay Description:Displacement of [3H]-CGS21680 from human adenosine A2A receptor expressed in HEK293 cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.86E+3nMAssay Description:Displacement of [3H]-CGS21680 from human adenosine A2A receptor expressed in HEK293 cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.15E+3nMAssay Description:Displacement of [3H]-CGS21680 from human adenosine A2A receptor expressed in HEK293 cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.31E+3nMAssay Description:Displacement of [3H]-CGS21680 from human adenosine A2A receptor expressed in HEK293 cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 7.49E+3nMAssay Description:Displacement of [3H]-CGS21680 from human adenosine A2A receptor expressed in HEK293 cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0700nMAssay Description:Reversal of P-gp mediated multidrug resistance in human DU145-TxR cells overexpressing P-gp assessed as potentiation of paclitaxel-induced cytotoxici...More data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells assessed as reduction in veratridine-induced depolarization preincubated for 15 to 20...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:i. PARP1 assay: Human recombinant PARP1 at a final concentration of 2.5 nM was combined with histone H4 (20 μM) and test articles at various con...More data for this Ligand-Target Pair
Affinity DataIC50: 0.240nMAssay Description:Inhibition of matrix metalloprotease-12More data for this Ligand-Target Pair
Affinity DataIC50: 0.260nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:i. PARP1 assay: Human recombinant PARP1 at a final concentration of 2.5 nM was combined with histone H4 (20 μM) and test articles at various con...More data for this Ligand-Target Pair
Affinity DataIC50: 0.350nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
Affinity DataIC50: 0.370nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells assessed as reduction in veratridine-induced depolarization preincubated for 15 to 20...More data for this Ligand-Target Pair