Affinity DataKi: 1.5nMAssay Description:The compound was evaluated for binding affinity against ProthrombinMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:The compound was evaluated for binding affinity against ProthrombinMore data for this Ligand-Target Pair
Affinity DataKi: 125nMAssay Description:Concentration required for 50 percent inhibition of ProthrombinMore data for this Ligand-Target Pair
Affinity DataKi: 125nMAssay Description:The compound was evaluated for binding affinity against ProthrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 0.00170nMAssay Description:In vitro inhibitory concentration of compound against human thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:In vitro binding activity against dopamine receptor D2 from homogenized rat brain, using [3H]spiperone as the radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of G£Teborg
Curated by ChEMBL
University Of G£Teborg
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:In vitro binding activity against 5-hydroxytryptamine 1A receptor receptor from homogenized rat brain, using [3H]8-OH-DPAT as the radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:In vitro inhibitory concentration of compound against human thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 5.80nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Concentration required for 50 percent inhibition of ProthrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Compound was tested for inhibitory activity against ThrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Compound was tested for inhibitory activity against ThrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of G£Teborg
Curated by ChEMBL
University Of G£Teborg
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:In vitro binding activity against 5-hydroxytryptamine 1A receptor from homogenized rat brain, using [3H]-8-OH-DPAT as the radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of G£Teborg
Curated by ChEMBL
University Of G£Teborg
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:In vitro binding activity against 5-hydroxytryptamine 1A receptor from homogenized rat brain, using [3H]8-OH-DPAT as the radioligand.More data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant human NaV1.7 alpha subunit expressed in HEK293 cells at -65 mV holding potential by patch clamp electrophysiological assayMore data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:Inhibition of recombinant human NaV1.7 alpha subunit expressed in HEK293 cells at -65 mV holding potential by patch clamp electrophysiological assayMore data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:In vitro inhibitory concentration of compound against human thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Inhibition of recombinant human NaV1.7 alpha subunit expressed in HEK293 cells at -65 mV holding potential by patch clamp electrophysiological assayMore data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Inhibition of recombinant human NaV1.7 alpha subunit expressed in HEK293 cells at -65 mV holding potential by patch clamp electrophysiological assayMore data for this Ligand-Target Pair
Affinity DataIC50: 64nMAssay Description:Inhibition of recombinant human NaV1.7 alpha subunit expressed in HEK293 cells at -65 mV holding potential by patch clamp electrophysiological assayMore data for this Ligand-Target Pair
Affinity DataIC50: 69nMAssay Description:In vitro binding activity against Dopamine receptor D1 from homogenized rat brain, using [3H]SCH-23390 as the radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 73nMAssay Description:Inhibition of recombinant human NaV1.7 alpha subunit expressed in HEK293 cells at -65 mV holding potential by patch clamp electrophysiological assayMore data for this Ligand-Target Pair
Affinity DataIC50: 73nMAssay Description:In vitro inhibitory concentration of compound against human thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 74nMAssay Description:Inhibition of recombinant rat NaV1.7 alpha subunit expressed in HEK293 cells at -65 mV holding potential by patch clamp electrophysiological assayMore data for this Ligand-Target Pair
Affinity DataIC50: 74nMAssay Description:Inhibition of recombinant rat NaV1.7 alpha subunit expressed in HEK293 cells at -65 mV holding potential by patch clamp electrophysiological assayMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant human NaV1.7 alpha subunit expressed in HEK293 cells at -90 mV holding potential by patch clamp electrophysiological assayMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant human NaV1.7 alpha subunit expressed in HEK293 cells at -90 mV holding potential by patch clamp electrophysiological assayMore data for this Ligand-Target Pair
Affinity DataIC50: 82nMAssay Description:Inhibition of recombinant human NaV1.7 alpha subunit expressed in HEK293 cells at -65 mV holding potential by patch clamp electrophysiological assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of G£Teborg
Curated by ChEMBL
University Of G£Teborg
Curated by ChEMBL
Affinity DataIC50: 82nMAssay Description:In vitro binding activity against 5-hydroxytryptamine 1A receptor from homogenized rat brain, using [3H]8-OH-DPAT as the radioligand.More data for this Ligand-Target Pair
Affinity DataIC50: 82nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 87nMAssay Description:Inhibition of recombinant human NaV1.7 alpha subunit expressed in HEK293 cells at -65 mV holding potential by patch clamp electrophysiological assayMore data for this Ligand-Target Pair
Affinity DataIC50: 91nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 92nMAssay Description:Inhibition of recombinant human NaV1.7 alpha subunit expressed in HEK293 cells at -65 mV holding potential by patch clamp electrophysiological assayMore data for this Ligand-Target Pair