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Found 253 with Last Name = 'nolan' and Initial = 'ka'
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
University of Manchester

LigandPNGBDBM35536(symmetric dicoumarol analogue, 12)
Affinity DataIC50:  0.180nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
University of Manchester

LigandPNGBDBM35534(symmetric dicoumarol analogue, 10)
Affinity DataIC50:  0.410nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
University of Manchester

LigandPNGBDBM35537(symmetric dicoumarol analogue, 13)
Affinity DataIC50:  0.420nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
University of Manchester

LigandPNGBDBM35544(4-hydroxy-2H-chromen-2-one core, 20)
Affinity DataIC50:  2.20nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
University of Manchester

LigandPNGBDBM35541(4-hydroxy-2H-chromen-2-one core, 17)
Affinity DataIC50:  2.5nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
University of Manchester

LigandPNGBDBM35525(3,3''''-methylenebis(4-hydroxy-coumarin | 3,3''''-...)
Affinity DataIC50:  2.60nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
MMDB

TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
University of Manchester

LigandPNGBDBM35527(symmetric dicoumarol analogue, 3)
Affinity DataIC50:  2.80nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
University of Manchester

LigandPNGBDBM35531(symmetric dicoumarol analogue, 7)
Affinity DataIC50:  3.80nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
University of Manchester

LigandPNGBDBM35530(symmetric dicoumarol analogue, 6)
Affinity DataIC50:  4.5nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
University of Manchester

LigandPNGBDBM35533(symmetric dicoumarol analogue, 9)
Affinity DataIC50:  4.90nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
University of Manchester

LigandPNGBDBM50055714(3-(4,7-dihydroxy-2-oxo-2H-3-chromenylmethyl)-4,7-d...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant NQO1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
University of Manchester

LigandPNGBDBM35525(3,3''''-methylenebis(4-hydroxy-coumarin | 3,3''''-...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant NQO1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
MMDB

TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
The University Of Manchester And Manchester Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50317140(5-(2-(diethylamino)ethylamino)-7-hydroxy-8,9-dimet...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
University of Manchester

LigandPNGBDBM35547(4-hydroxy-2H-chromen-2-one core, 23)
Affinity DataIC50:  6nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
University of Manchester

LigandPNGBDBM35529(symmetric dicoumarol analogue, 5)
Affinity DataIC50:  6nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
University of Manchester

LigandPNGBDBM35546(4-hydroxy-2H-chromen-2-one core, 22)
Affinity DataIC50:  6.30nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
University of Manchester

LigandPNGBDBM35543(4-hydroxy-2H-chromen-2-one core, 19)
Affinity DataIC50:  6.30nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
University of Manchester

LigandPNGBDBM35540(4-hydroxy-2H-chromen-2-one core, 16)
Affinity DataIC50:  7.70nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
The University Of Manchester And Manchester Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50008356(5-(2-(diethylamino)ethylamino)-8-methoxy-1-methyl-...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
University of Manchester

LigandPNGBDBM35532(symmetric dicoumarol analogue, 8)
Affinity DataIC50:  9nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
University of Manchester

LigandPNGBDBM35552(4-hydroxy-2H-chromen-2-one core, 29)
Affinity DataIC50:  9.90nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
University of Manchester

LigandPNGBDBM35528(symmetric dicoumarol analogue, 4)
Affinity DataIC50:  11nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
University of Manchester

LigandPNGBDBM35526(symmetric dicoumarol analogue, 2)
Affinity DataIC50:  14nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
University of Manchester

LigandPNGBDBM35550(4-hydroxy-2H-chromen-2-one core, 26)
Affinity DataIC50:  14nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
The University Of Manchester And Manchester Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50354527(CHEMBL1836819)
Affinity DataIC50:  14nMAssay Description:Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
University of Manchester

LigandPNGBDBM35548(4-hydroxy-2H-chromen-2-one core, 24)
Affinity DataIC50:  15nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
The University Of Manchester And Manchester Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50008344(5-(2-(diethylamino)ethylamino)-8-hydroxy-1-methyl-...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
The University Of Manchester And Manchester Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50317138(5-(2-(diethylamino)ethylamino)-7,10-dimethoxy-6H-i...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
University of Manchester

LigandPNGBDBM35549(4-hydroxy-2H-chromen-2-one core, 25)
Affinity DataIC50:  24nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
The University Of Manchester And Manchester Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50317139(5-(2-(diethylamino)ethylamino)-7-hydroxy-10-methox...)
Affinity DataIC50:  31nMAssay Description:Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
University of Manchester

LigandPNGBDBM35551(4-hydroxy-2H-chromen-2-one core, 28)
Affinity DataIC50:  31nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
University of Manchester

LigandPNGBDBM35545(4-hydroxy-2H-chromen-2-one core, 21)
Affinity DataIC50:  35nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
University of Manchester

LigandPNGBDBM35527(symmetric dicoumarol analogue, 3)
Affinity DataIC50:  38nMpH: 7.5 T: 2°CAssay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
University of Manchester

LigandPNGBDBM35542(4-hydroxy-2H-chromen-2-one core, 18)
Affinity DataIC50:  39nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
The University Of Manchester And Manchester Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50354535(CHEMBL1836822)
Affinity DataIC50:  42nMAssay Description:Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
The University Of Manchester And Manchester Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50354530(CHEMBL340884)
Affinity DataIC50:  46nMAssay Description:Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
The University Of Manchester And Manchester Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50354539(CHEMBL1836826)
Affinity DataIC50:  47nMAssay Description:Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
The University Of Manchester And Manchester Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50008352(5-(2-(dimethylamino)ethylamino)-8-hydroxy-1-methyl...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
The University Of Manchester And Manchester Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50008344(5-(2-(diethylamino)ethylamino)-8-hydroxy-1-methyl-...)
Affinity DataIC50:  54nMAssay Description:Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
The University Of Manchester And Manchester Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50354538(CHEMBL1836825)
Affinity DataIC50:  56nMAssay Description:Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
The University Of Manchester And Manchester Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50354528(CHEMBL125750)
Affinity DataIC50:  59nMAssay Description:Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometryMore data for this Ligand-Target Pair
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
University of Manchester

LigandPNGBDBM35535(symmetric dicoumarol analogue, 11)
Affinity DataIC50:  62nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
The University Of Manchester And Manchester Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50354536(CHEMBL1836823)
Affinity DataIC50:  73nMAssay Description:Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
The University Of Manchester And Manchester Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50354532(CHEMBL1836818)
Affinity DataIC50:  74nMAssay Description:Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
The University Of Manchester And Manchester Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM83846(5-(2-(dimethylamino)ethylamino)-8-hydroxy-6H-imida...)
Affinity DataIC50:  83nMAssay Description:Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
The University Of Manchester And Manchester Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50354531(CHEMBL1836817)
Affinity DataIC50:  83nMAssay Description:Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
The University Of Manchester And Manchester Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50317134(5-(2-(dimethylamino)ethylamino)-1-methyl-6H-imidaz...)
Affinity DataIC50:  90nMAssay Description:Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
The University Of Manchester And Manchester Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50008352(5-(2-(dimethylamino)ethylamino)-8-hydroxy-1-methyl...)
Affinity DataIC50:  90nMAssay Description:Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
University of Manchester

LigandPNGBDBM50309775(5-(isopentylamino)-6H-[1,2,3]triazolo[4,5,1-de]acr...)
Affinity DataIC50:  92nMAssay Description:Inhibition of human recombinant NQO1 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
University of Manchester

LigandPNGBDBM50309777(5-(2-(dimethylamino)ethylamino)-6H-[1,2,3]triazolo...)
Affinity DataIC50:  94nMAssay Description:Inhibition of human recombinant NQO1 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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