Affinity DataKi: 1.26nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.26nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.16nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.01nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.31nMAssay Description:Inhibition of rat EP3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 7.94nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 12.6nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 12.6nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 15.8nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 19.9nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 25.1nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 79.4nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Inhibition of human EP3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 158nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 398nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 501nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 631nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 794nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.26E+3nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+3nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human TP receptor by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human DP receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human EP4 receptor by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human EP2 receptor by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of human FP receptorMore data for this Ligand-Target Pair
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of human TP receptorMore data for this Ligand-Target Pair
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of human EP4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of human EP1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of human DP receptorMore data for this Ligand-Target Pair
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of human IP receptorMore data for this Ligand-Target Pair
Affinity DataKi: >2.51E+4nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: >2.51E+4nMAssay Description:Displacement of [3H]PGF2a from human recombinant FP receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: >2.51E+4nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: >2.51E+4nMAssay Description:Inhibition of human EP1 receptor by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Ability to inhibit recombinant human dihydrofolate reductase.More data for this Ligand-Target Pair
TargetMacrophage metalloelastase(Homo sapiens (Human))
University Of California Riverside
Curated by ChEMBL
University Of California Riverside
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of recombinant human MMP12 catalytic domain (Gly106 to Gly263 residues) expressed in Escherichia coli BL21 Codon Plus cells using 5-FAM/QX...More data for this Ligand-Target Pair
TargetMacrophage metalloelastase(Homo sapiens (Human))
University Of California Riverside
Curated by ChEMBL
University Of California Riverside
Curated by ChEMBL
Affinity DataIC50: 4.40nMAssay Description:Inhibition of recombinant human MMP12 catalytic domain (Gly106 to Gly263 residues) expressed in Escherichia coli BL21 Codon Plus cells using 5-FAM/QX...More data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Inhibitory concentration against dihydrofolate reductase DHFR from rat liver.More data for this Ligand-Target Pair
TargetMacrophage metalloelastase(Homo sapiens (Human))
University Of California Riverside
Curated by ChEMBL
University Of California Riverside
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Inhibition of recombinant human MMP12 catalytic domain (Gly106 to Gly263 residues) expressed in Escherichia coli BL21 Codon Plus cells using 5-FAM/QX...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of SGK1 by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Concentration required to inhibit [125I]IL-8 binding towards C-X-C chemokine receptor type 2 of human expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibitory concentration against dihydrofolate reductase DHFR from rat liver.More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Uppsala University
Curated by ChEMBL
Uppsala University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration against dihydrofolate reductase DHFR from T. gondiiMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Concentration required to inhibit [125I]IL-8 binding towards C-X-C chemokine receptor type 2 of human expressed in CHO cellsMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Uppsala University
Curated by ChEMBL
Uppsala University
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibitory concentration against dihydrofolate reductase DHFR from T. gondiiMore data for this Ligand-Target Pair