TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
European Molecular Biology Laboratory
Curated by ChEMBL
European Molecular Biology Laboratory
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of dye-labeled tracer binding to HDAC10 (unknown origin) transfected in human HeLa cells measured after 2 hrs by nano-luciferase reporter ...More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
European Molecular Biology Laboratory
Curated by ChEMBL
European Molecular Biology Laboratory
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of tubastatin-Alexa647-tracer binding to recombinant GST-tagged HDAC10 (unknown origin) measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
European Molecular Biology Laboratory
Curated by ChEMBL
European Molecular Biology Laboratory
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of dye-labeled tracer binding to HDAC10 (unknown origin) transfected in human HeLa cells measured after 2 hrs by nano-luciferase reporter ...More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
European Molecular Biology Laboratory
Curated by ChEMBL
European Molecular Biology Laboratory
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of tubastatin-Alexa647-tracer binding to recombinant GST-tagged HDAC10 (unknown origin) measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
European Molecular Biology Laboratory
Curated by ChEMBL
European Molecular Biology Laboratory
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of tubastatin-Alexa647-tracer binding to recombinant GST-tagged HDAC10 (unknown origin) measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
European Molecular Biology Laboratory
Curated by ChEMBL
European Molecular Biology Laboratory
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of dye-labeled tracer binding to HDAC10 (unknown origin) transfected in human HeLa cells measured after 2 hrs by nano-luciferase reporter ...More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
European Molecular Biology Laboratory
Curated by ChEMBL
European Molecular Biology Laboratory
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of tubastatin-Alexa647-tracer binding to recombinant GST-tagged HDAC10 (unknown origin) measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
European Molecular Biology Laboratory
Curated by ChEMBL
European Molecular Biology Laboratory
Curated by ChEMBL
Affinity DataIC50: 7.90nMAssay Description:Inhibition of dye-labeled tracer binding to HDAC10 (unknown origin) transfected in human HeLa cells measured after 2 hrs by nano-luciferase reporter ...More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
European Molecular Biology Laboratory
Curated by ChEMBL
European Molecular Biology Laboratory
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of tubastatin-Alexa647-tracer binding to recombinant GST-tagged HDAC10 (unknown origin) measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Danio rerio)
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of zebra fish HDAC10 using Ac-spermidine-AMC as substrate incubated for 25 mins and measured by fluorescence assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
European Molecular Biology Laboratory
Curated by ChEMBL
European Molecular Biology Laboratory
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of tubastatin-Alexa647-tracer binding to recombinant GST-tagged HDAC10 (unknown origin) measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
European Molecular Biology Laboratory
Curated by ChEMBL
European Molecular Biology Laboratory
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of dye-labeled tracer binding to HDAC10 (unknown origin) transfected in human HeLa cells measured after 2 hrs by nano-luciferase reporter ...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human HDAC6 using RHKKAc peptide as substrateMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
European Molecular Biology Laboratory
Curated by ChEMBL
European Molecular Biology Laboratory
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of dye-labeled tracer binding to HDAC10 (unknown origin) transfected in human HeLa cells measured after 2 hrs by nano-luciferase reporter ...More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
European Molecular Biology Laboratory
Curated by ChEMBL
European Molecular Biology Laboratory
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of tubastatin-Alexa647-tracer binding to recombinant GST-tagged HDAC10 (unknown origin) measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Danio rerio)
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of zebra fish HDAC10 using Ac-spermidine-AMC as substrate incubated for 25 mins and measured by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of dye-labeled tracer binding to HDAC6 (unknown origin) transfected in human HeLa cells measured after 2 hrs by nano-luciferase reporter g...More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
European Molecular Biology Laboratory
Curated by ChEMBL
European Molecular Biology Laboratory
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of tubastatin-Alexa647-tracer binding to recombinant GST-tagged HDAC10 (unknown origin) measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Danio rerio)
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of zebra fish HDAC10 using Ac-spermidine-AMC as substrate incubated for 25 mins and measured by fluorescence assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
European Molecular Biology Laboratory
Curated by ChEMBL
European Molecular Biology Laboratory
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of dye-labeled tracer binding to HDAC10 (unknown origin) transfected in human HeLa cells measured after 2 hrs by nano-luciferase reporter ...More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
European Molecular Biology Laboratory
Curated by ChEMBL
European Molecular Biology Laboratory
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of tubastatin-Alexa647-tracer binding to recombinant GST-tagged HDAC10 (unknown origin) measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of human HDAC8 (1 to 377 residues) expressed in Escherichia coli BL21(DE3) using Boc-Lys(TFA)-AMC as substrate preincubated for 5 mins fol...More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Danio rerio)
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of zebra fish HDAC10 using Ac-spermidine-AMC as substrate incubated for 25 mins and measured by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of dye-labeled tracer binding to HDAC6 (unknown origin) transfected in human HeLa cells measured after 2 hrs by nano-luciferase reporter g...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in baculovirus infected insect cells measured after 40 mins by HDAC...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of dye-labeled tracer binding to HDAC6 (unknown origin) transfected in human HeLa cells measured after 2 hrs by nano-luciferase reporter g...More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Danio rerio)
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of zebra fish HDAC10 using Ac-spermidine-AMC as substrate incubated for 25 mins and measured by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of recombinant human HDAC6 using ZMAL (Z-(Ac)Lys-AMC as substrate incubated for 20 mins and measured by homogenous fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Danio rerio)
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of zebra fish HDAC10 using Ac-spermidine-AMC as substrate incubated for 25 mins and measured by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...More data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
European Molecular Biology Laboratory
Curated by ChEMBL
European Molecular Biology Laboratory
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant full length C-terminal His-tagged HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) express...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of dye-labeled tracer binding to HDAC6 (unknown origin) transfected in human HeLa cells measured after 2 hrs by nano-luciferase reporter g...More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
European Molecular Biology Laboratory
Curated by ChEMBL
European Molecular Biology Laboratory
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of dye-labeled tracer binding to HDAC10 (unknown origin) transfected in human HeLa cells measured after 2 hrs by nano-luciferase reporter ...More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Danio rerio)
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of zebra fish HDAC10 using Ac-spermidine-AMC as substrate incubated for 25 mins and measured by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
European Molecular Biology Laboratory
Curated by ChEMBL
European Molecular Biology Laboratory
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant full-length C-terminal FLAG-fused/His-tagged human HDAC1 expressed in baculovirus infected Sf9 insect cells measured after ...More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
European Molecular Biology Laboratory
Curated by ChEMBL
European Molecular Biology Laboratory
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of dye-labeled tracer binding to HDAC10 (unknown origin) transfected in human HeLa cells measured after 2 hrs by nano-luciferase reporter ...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Affinity DataIC50: 53nMAssay Description:Inhibition of human HDAC6 using (Z-(Ac)Lys-AMC) as substrate after 90 mins by fluorescence analysisMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:Inhibition of recombinant human full length N-terminal His6/SUMO-tagged HDAC8 expressed in Escherichia coli BL21 DE3 using Boc-Lys(Ac)-AMC as substra...More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Danio rerio)
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of zebra fish HDAC10 using Ac-spermidine-AMC as substrate incubated for 25 mins and measured by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Affinity DataIC50: 59nMAssay Description:Inhibition of human HDAC6 using (Z-(Ac)Lys-AMC) as substrate after 90 mins by fluorescence analysisMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Danio rerio)
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of zebra fish HDAC10 using Ac-spermidine-AMC as substrate incubated for 25 mins and measured by fluorescence assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Danio rerio)
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 62nMAssay Description:Inhibition of zebra fish HDAC10 using Ac-spermidine-AMC as substrate incubated for 25 mins and measured by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of dye-labeled tracer binding to HDAC6 (unknown origin) transfected in human HeLa cells measured after 2 hrs by nano-luciferase reporter g...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of dye-labeled tracer binding to HDAC6 (unknown origin) transfected in human HeLa cells measured after 2 hrs by nano-luciferase reporter g...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of dye-labeled tracer binding to HDAC6 (unknown origin) transfected in human HeLa cells measured after 2 hrs by nano-luciferase reporter g...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of dye-labeled tracer binding to HDAC6 (unknown origin) transfected in human HeLa cells measured after 2 hrs by nano-luciferase reporter g...More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
European Molecular Biology Laboratory
Curated by ChEMBL
European Molecular Biology Laboratory
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of tubastatin-Alexa647-tracer binding to recombinant GST-tagged HDAC10 (unknown origin) measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 69nMAssay Description:Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...More data for this Ligand-Target Pair