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Found 17 with Last Name = 'okamura' and Initial = 'n'
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Ge Healthcare

US Patent
LigandPNGBDBM247405(US9452985, THK-5125)
Affinity DataKi:  9.20nM ΔG°:  -45.9kJ/moleT: 2°CAssay Description:For tau imaging probes other than THK-5105, binding to K18-ΔK280 aggregates was evaluated with a competitive binding test using [18F] THK-5105 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Ge Healthcare

US Patent
LigandPNGBDBM247403(US9452985, THK-5117)
Affinity DataKi:  10.5nM ΔG°:  -45.5kJ/moleT: 2°CAssay Description:For tau imaging probes other than THK-5105, binding to K18-ΔK280 aggregates was evaluated with a competitive binding test using [18F] THK-5105 a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Ge Healthcare

US Patent
LigandPNGBDBM247407(US9452985, THK-5129)
Affinity DataKi:  21.4nM ΔG°:  -43.8kJ/moleT: 2°CAssay Description:For tau imaging probes other than THK-5105, binding to K18-ΔK280 aggregates was evaluated with a competitive binding test using [18F] THK-5105 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Ge Healthcare

US Patent
LigandPNGBDBM247404(US9452985, THK-5122)
Affinity DataKi:  34.9nM ΔG°:  -42.6kJ/moleT: 2°CAssay Description:For tau imaging probes other than THK-5105, binding to K18-ΔK280 aggregates was evaluated with a competitive binding test using [18F] THK-5105 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Ge Healthcare

US Patent
LigandPNGBDBM247402(US9452985, THK-5116)
Affinity DataKi:  36nM ΔG°:  -42.5kJ/moleT: 2°CAssay Description:For tau imaging probes other than THK-5105, binding to K18-ΔK280 aggregates was evaluated with a competitive binding test using [18F] THK-5105 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Ge Healthcare

US Patent
LigandPNGBDBM247406(US9452985, THK-5151)
Affinity DataKi:  40.1nM ΔG°:  -42.2kJ/moleT: 2°CAssay Description:For tau imaging probes other than THK-5105, binding to K18-ΔK280 aggregates was evaluated with a competitive binding test using [18F] THK-5105 a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Ge Healthcare

US Patent
LigandPNGBDBM247408(US9452985, THK-523 (reference for comparison))
Affinity DataKi:  59.3nM ΔG°:  -41.2kJ/moleT: 2°CAssay Description:For tau imaging probes other than THK-5105, binding to K18-ΔK280 aggregates was evaluated with a competitive binding test using [18F] THK-5105 a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Ge Healthcare

US Patent
LigandPNGBDBM50185987(2-(1-(6-((2-fluoroethyl)(methyl)amino)naphthalen-2...)
Affinity DataKi:  256nM ΔG°:  -37.6kJ/moleT: 2°CAssay Description:For tau imaging probes other than THK-5105, binding to K18-ΔK280 aggregates was evaluated with a competitive binding test using [18F] THK-5105 a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAldo-keto reductase family 1 member B1(Sus scrofa)
Fukuyama University

Curated by ChEMBL
LigandPNGBDBM50292354(CHEMBL463755 | Isorhamnetin 3,7-disulfate)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of pig lens aldose reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Sus scrofa)
Fukuyama University

Curated by ChEMBL
LigandPNGBDBM50292357(CHEMBL458251 | Tamarixetin 3-glucoside-7-sulfate)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of pig lens aldose reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Sus scrofa)
Fukuyama University

Curated by ChEMBL
LigandPNGBDBM50241354(2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-3-(3,4,5-tr...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of pig lens aldose reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Sus scrofa)
Fukuyama University

Curated by ChEMBL
LigandPNGBDBM50292356(CHEMBL457815 | Rhamnazin-3-sulfate)
Affinity DataIC50:  3.01E+4nMAssay Description:Inhibition of pig lens aldose reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Sus scrofa)
Fukuyama University

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)
Affinity DataIC50:  5.01E+4nMAssay Description:Inhibition of pig lens aldose reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Sus scrofa)
Fukuyama University

Curated by ChEMBL
LigandPNGBDBM50292352(CHEMBL463753 | potassium 2-(3,4-dihydroxyphenyl)-5...)
Affinity DataIC50:  5.09E+4nMAssay Description:Inhibition of pig lens aldose reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Sus scrofa)
Fukuyama University

Curated by ChEMBL
LigandPNGBDBM50292353(CHEMBL471479 | Percicarin | Persicarin)
Affinity DataIC50:  6.90E+4nMAssay Description:Inhibition of pig lens aldose reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Sus scrofa)
Fukuyama University

Curated by ChEMBL
LigandPNGBDBM50292355(CHEMBL457148 | Rhamnazin)
Affinity DataIC50: >9.10E+4nMAssay Description:Inhibition of pig lens aldose reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Sus scrofa)
Fukuyama University

Curated by ChEMBL
LigandPNGBDBM23409(3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-...)
Affinity DataIC50: >9.50E+4nMAssay Description:Inhibition of pig lens aldose reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed