Compile Data Set for Download or QSAR
maximum 50k data
Found 486 with Last Name = 'okuzumi' and Initial = 't'
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM15131(5-indazolyl pyridine 3 | 5-{5-[(2S)-2-amino-3-(1H-...)
Affinity DataKi:  0.160nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611197((2S)-1-(5-fluorobenzofuran-2- yl)sulfonyl-N-[[3-[5...)
Affinity DataIC50:  0.380nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611196((2S)-1-(5-fluorobenzofuran-2- yl)sulfonyl-N-[[3-[6...)
Affinity DataIC50:  0.410nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611264((2S)-1-(5-fluorobenzofuran-2- yl)sulfonyl-N-[[3-[4...)
Affinity DataIC50:  0.480nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611236((2S)-1-(5-fluorobenzofuran-2- yl)sulfonyl-N-[[2-[4...)
Affinity DataIC50:  0.610nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611235((2S)-1-(5-fluorobenzofuran-2- yl)sulfonyl-N-[[2-[4...)
Affinity DataIC50:  0.610nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611331((2S)-1-(5-fluorobenzofuran-2- yl)sulfonyl-N-[[6-[6...)
Affinity DataIC50:  0.660nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611205((2S)-1-(5-fluorobenzofuran-2- yl)sulfonyl-N-[[2-[4...)
Affinity DataIC50:  0.760nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611240((2S)-1-(5-fluorobenzofuran-2- yl)sulfonyl-N-[[2-[6...)
Affinity DataIC50:  0.830nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611265((2S)-1-(5-fluorobenzofuran-2- yl)sulfonyl-N-[[3-[4...)
Affinity DataIC50:  0.830nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611198((2S)-1-(5-fluorobenzofuran-2- yl)sulfonyl-N-[[6-[4...)
Affinity DataIC50:  0.840nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611330((2S)-1-(5-fluorobenzofuran-2- yl)sulfonyl-N-[[4-[5...)
Affinity DataIC50:  0.880nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611245((2S)-1-(5-fluorobenzofuran-2- yl)sulfonyl-N-[[2-[2...)
Affinity DataIC50:  0.970nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611095((2S)-N-[[3-[(4-cyanophenyl) methoxy]phenyl]methyl]...)
Affinity DataIC50:  1nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611366((1S,3S,5S)-4-(5- fluorobenzofuran-2-yl)sulfonyl- N...)
Affinity DataIC50:  1.20nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611193((2S)-1-(benzofuran-2-ylsulfonyl)- N-[[6-[4-(triflu...)
Affinity DataIC50:  1.20nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611192((2S)-1-(benzofuran-2-ylsulfonyl)- N-[[3-[5-(triflu...)
Affinity DataIC50:  1.20nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611154((2S)-1-(5-fluorobenzofuran-2- yl)sulfonyl-N-[[3-[[...)
Affinity DataIC50:  1.30nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611332((2S)-1-(5-fluorobenzofuran-2- yl)sulfonyl-N-[[4-[5...)
Affinity DataIC50:  1.30nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611286((2S)-1-(benzofuran-2- ylsulfonyl)-N-[[4-[5- (trifl...)
Affinity DataIC50:  1.30nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611396((2S)-1-(5-fluorobenzofuran-2- yl)sulfonyl-N-[[6-[2...)
Affinity DataIC50:  1.40nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611133((2S)-1-(5-fluorobenzofuran- 2-yl)sulfonyl-N-[[3-[[...)
Affinity DataIC50:  1.40nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611149((2S)-N-[[3-[(4- cyanophenyl)methoxy]- 5-fluoro- ph...)
Affinity DataIC50:  1.5nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611256((2S)-1-(5-fluorobenzofuran-2- yl)sulfonyl-N-[[4-[6...)
Affinity DataIC50:  1.5nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611147((2S)-N-[(3-benzyloxy-5- fluoro-phenyl)methyl]- 1-(...)
Affinity DataIC50:  1.60nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611380((2S)-1-furo[3,2-c]pyridin-2- ylsulfonyl-N-[[4-hydr...)
Affinity DataIC50:  1.60nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611207((2S)-1-(5-fluorobenzofuran-2- yl)sulfonyl-N-[[3-[6...)
Affinity DataIC50:  1.60nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611156((2S)-N-[(3-benzyloxyphenyl) methyl]-1-(5-fluoroben...)
Affinity DataIC50:  1.60nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611191((2S)-1-(benzofuran-2-ylsulfonyl)- N-[[3-[6-(triflu...)
Affinity DataIC50:  1.60nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611413((2S)-1-(benzofuran-2-ylsulfonyl)-N-[[4- fluoro-3-[...)
Affinity DataIC50:  1.70nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611157((2S)-1-(benzofuran-2- ylsulfonyl)-N-[[3-[[4- (trif...)
Affinity DataIC50:  1.70nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611365((1R,3S,5R)-4-(5- fluorobenzofuran-2-yl)sulfonyl- N...)
Affinity DataIC50:  1.90nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611258((2S)-1-(benzofuran-2- ylsulfonyl)-N-[[4-[6- (trifl...)
Affinity DataIC50:  1.90nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611237((2S)-N-[[2-[4- (difluoromethoxy)phenyl]-4- pyridyl...)
Affinity DataIC50:  2nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611263((2S)-N-[[3-(4- chlorophenyl)phenyl]methyl]-1- (5-f...)
Affinity DataIC50:  2.10nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611322((2S)-1-(benzofuran-2- ylsulfonyl)-N-[[5-hydroxy-4-...)
Affinity DataIC50:  2.10nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611255((2S)-1-(5-fluorobenzofuran-2- yl)sulfonyl-N-[[4-[4...)
Affinity DataIC50:  2.20nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611247((2S)-1-(5-fluorobenzofuran-2- yl)sulfonyl-N-[[5-[6...)
Affinity DataIC50:  2.20nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611199((2S)-1-(4-fluorobenzofuran-2- yl)sulfonyl-N-[[3-[6...)
Affinity DataIC50:  2.20nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611300(Synthesis of (2S)-1-(benzofuran-2-ylsulfonyl)-N-[[...)
Affinity DataIC50:  2.20nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611369((1S,2S,4R)-3-(5- fluorobenzofuran-2-yl)sulfonyl- N...)
Affinity DataIC50:  2.30nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611222((2S)-1-(benzofuran-2- ylsulfonyl)-N-[[2-[4- (trifl...)
Affinity DataIC50:  2.40nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611329((2S)-1-(5-fluorobenzofuran-2- yl)sulfonyl-N-[[4-[4...)
Affinity DataIC50:  2.40nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611395((2S)-1-(benzofuran-2-ylsulfonyl)-N- [[6-[2-hydroxy...)
Affinity DataIC50:  2.5nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM15131(5-indazolyl pyridine 3 | 5-{5-[(2S)-2-amino-3-(1H-...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of myristoylated wild type AKT1 expressed in HEK293T cells by in-vitro immunoprecipitation kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611416(Synthesis of (2S)-1-(benzofuran-2-ylsulfonyl)-N-[[...)
Affinity DataIC50:  2.5nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611302((2S)-1-(benzofuran-2- ylsulfonyl)-N-[[3-[2- (trifl...)
Affinity DataIC50:  2.5nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611505((2S)-1-(5-fluorobenzofuran-2- yl)sulfonyl-N-[[3-[5...)
Affinity DataIC50:  2.5nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611230((2S)-1-(benzofuran-2- ylsulfonyl)-N-[[2-[2-hydroxy...)
Affinity DataIC50:  2.60nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM611166((2S)-1-(5-fluorobenzofuran-2- yl)sulfonyl-N-[[3-[4...)
Affinity DataIC50:  2.70nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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