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Found 3257 with Last Name = 'orton' and Initial = 'd'
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50377655(CHEMBL260160)
Affinity DataKi:  0.00500nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50377635(CHEMBL402980)
Affinity DataKi:  0.0130nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50377637(CHEMBL257398)
Affinity DataKi:  0.0280nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50377629(CHEMBL260086)
Affinity DataKi:  0.0470nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50328717(5-Chloro-N-(5-chloro-pyridin-2-yl)-3-methoxy-2-[4-...)
Affinity DataKi:  0.0570nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50377638(CHEMBL257400)
Affinity DataKi:  0.0600nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50377628(CHEMBL261536)
Affinity DataKi:  0.0650nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM19023(1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-y...)
Affinity DataKi:  0.0800nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50377640(CHEMBL258196)
Affinity DataKi:  0.120nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50377656(CHEMBL259534)
Affinity DataKi:  0.140nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50377636(CHEMBL257399)
Affinity DataKi:  0.140nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50377631(CHEMBL256152)
Affinity DataKi:  0.140nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50377630(CHEMBL404448)
Affinity DataKi:  0.190nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50377643(CHEMBL257966)
Affinity DataKi:  0.210nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50377627(CHEMBL260369)
Affinity DataKi:  0.240nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50377632(CHEMBL404449)
Affinity DataKi:  0.330nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50377633(CHEMBL403075)
Affinity DataKi:  0.450nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(RAT)
Dvanderbilt Program In Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50403547(ATROPEN | ATROPINE)
Affinity DataKi:  0.520nMAssay Description:Displacement of [3H]NMS from rat recombinant muscarinic M4 receptor expressed in CHO cells after 2 hrs by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(RAT)
Dvanderbilt Program In Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50403547(ATROPEN | ATROPINE)
Affinity DataKi:  0.520nMAssay Description:Displacement of [3H]NMS from rat recombinant muscarinic M4 receptor expressed in CHO cells after 2 hrs by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50377646(CHEMBL259535)
Affinity DataKi:  0.580nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50377641(CHEMBL402836)
Affinity DataKi:  0.620nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M5(RAT)
Dvanderbilt Program In Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50403547(ATROPEN | ATROPINE)
Affinity DataKi:  0.860nMAssay Description:Displacement of [3H]NMS from rat recombinant muscarinic M5 receptor expressed in CHO cells after 2 hrs by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50377647(CHEMBL411044)
Affinity DataKi:  1nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50377652(CHEMBL256573)
Affinity DataKi:  1.10nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50377650(CHEMBL260354)
Affinity DataKi:  1.20nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50377644(CHEMBL1162978)
Affinity DataKi:  1.30nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50377634(CHEMBL428432)
Affinity DataKi:  2nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50377639(CHEMBL258188)
Affinity DataKi:  2.20nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50377649(CHEMBL260912)
Affinity DataKi:  3nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50377642(CHEMBL257967)
Affinity DataKi:  4.20nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50377653(CHEMBL402761)
Affinity DataKi:  5.5nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
TargetSynaptic vesicular amine transporter(Rattus norvegicus (Rat))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50017701(3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]MTBZ from VMAT2 in rat whole brain vesicles by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM22165(1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-pheny...)
Affinity DataKi:  18nMAssay Description:Inhibition of [3H]DA uptake at DAT in rat brain striatal synaptosomes by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSynaptic vesicular amine transporter(Rattus norvegicus (Rat))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50496673(CHEMBL3133793)
Affinity DataKi:  23nMAssay Description:Inhibition of [3H]DA uptake at VMAT2 in rat striatal synaptic vesiclesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSynaptic vesicular amine transporter(Rattus norvegicus (Rat))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50192902(2-ethyl-3-isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-he...)
Affinity DataKi:  28nMAssay Description:Inhibition of [3H]DTBZ binding to VMAT2 in rat synaptic vesicle membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSynaptic vesicular amine transporter(Rattus norvegicus (Rat))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50433783(CHEMBL2381721)
Affinity DataKi:  29nMAssay Description:Inhibition of [3H]DA uptake at VMAT2 in rat striatal synaptic vesiclesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSynaptic vesicular amine transporter(Rattus norvegicus (Rat))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50496681(CHEMBL3133789)
Affinity DataKi:  30nMAssay Description:Inhibition of [3H]DA uptake at VMAT2 in rat striatal synaptic vesiclesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSynaptic vesicular amine transporter(Rattus norvegicus (Rat))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50496675(CHEMBL3133795)
Affinity DataKi:  39nMAssay Description:Inhibition of [3H]DA uptake at VMAT2 in rat striatal synaptic vesiclesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM30130(CHEMBL1201082 | CHEMBL41 | Fluoxetin | Fluoxetine ...)
Affinity DataKi:  41nMAssay Description:Inhibition of [3H]5HT uptake at SERT in rat brain hippocampal synaptosomes by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSynaptic vesicular amine transporter(Rattus norvegicus (Rat))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50496680(CHEMBL3133797)
Affinity DataKi:  43nMAssay Description:Inhibition of [3H]DA uptake at VMAT2 in rat striatal synaptic vesiclesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50377648(CHEMBL260911)
Affinity DataKi:  43nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSynaptic vesicular amine transporter(Rattus norvegicus (Rat))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50171953((2R,6S)-2,6-Diphenethyl-piperidine | CHEMBL192329 ...)
Affinity DataKi:  44nMAssay Description:Inhibition of [3H]DA uptake at VMAT2 in rat striatal synaptic vesiclesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50192903(8R-hydroxylobel-9-ene | CHEMBL425617)
Affinity DataKi:  44nMAssay Description:Inhibition of [3H]DA uptake at DAT in rat brain striatal synaptosomes by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50192903(8R-hydroxylobel-9-ene | CHEMBL425617)
Affinity DataKi:  44nMAssay Description:Inhibition of [3H]5-HT uptake at SERT in rat hippocampal synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSynaptic vesicular amine transporter(Rattus norvegicus (Rat))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50080827((2R,6S)-1-Methyl-2,6-diphenethyl-piperidine | (2S,...)
Affinity DataKi:  45nMAssay Description:Inhibition of [3H]DA uptake at VMAT2 in rat striatal synaptic vesiclesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSynaptic vesicular amine transporter(Rattus norvegicus (Rat))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50496665(CHEMBL3133799)
Affinity DataKi:  48nMAssay Description:Inhibition of [3H]DA uptake at VMAT2 in rat striatal synaptic vesiclesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSynaptic vesicular amine transporter(Rattus norvegicus (Rat))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50496691(CHEMBL3133697)
Affinity DataKi:  54nMAssay Description:Inhibition of [3H]DA uptake at VMAT2 in rat striatal synaptic vesiclesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50377654(CHEMBL256574)
Affinity DataKi:  59nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSynaptic vesicular amine transporter(Rattus norvegicus (Rat))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50496686(CHEMBL3133794)
Affinity DataKi:  60nMAssay Description:Inhibition of [3H]DA uptake at VMAT2 in rat striatal synaptic vesiclesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSynaptic vesicular amine transporter(Rattus norvegicus (Rat))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50496694(CHEMBL3133689)
Affinity DataKi:  60nMAssay Description:Inhibition of [3H]DA uptake at VMAT2 in rat striatal synaptic vesiclesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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