Affinity DataKi: 400nMAssay Description:Inhibition of relaxation activities of DNA topoisomerase I with respect to pBR322 DNAMore data for this Ligand-Target Pair
Affinity DataKi: 7.41E+4nMAssay Description:Inhibition of relaxation activities of DNA topoisomerase II with respect to pBR322 DNAMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase II by detecting the conversion of supercoiled pBR322 DNA to its relaxed for...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of SIRT2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of human SIRT2 expressed in Escherichia coli BL21 using acetyl-H3K9 by HPLC based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR (695 to end residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 G...More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of human SIRT2 deacetylase activity using QPKKac as substrateMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
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Ligand Info
Affinity DataIC50: 70nMAssay Description:Inhibition of human SIRT2 deacetylase activity using QPKKac as substrateMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
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Ligand Info
Affinity DataIC50: 78nMAssay Description:Inhibition of human SIRT2 deacetylase activity measured after preincubation by HPLC methodMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
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Ligand Info
Affinity DataIC50: 90nMAssay Description:Inhibition of human SIRT2 demyristoylation activity using ETDKac as substrateMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
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Ligand Info
Affinity DataIC50: 93nMAssay Description:Inhibition of human SIRT2 deacetylase activity measured after preincubation by HPLC methodMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
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Ligand Info
Affinity DataIC50: 110nMAssay Description:Inhibition of human SIRT2 defatty-acylase activity measured after preincubation by HPLC methodMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
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Ligand Info
Affinity DataIC50: 150nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase II by detecting the conversion of supercoiled pBR322 DNA to its relaxed for...More data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of human SIRT2 defatty-acylase activity measured after preincubation by HPLC methodMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
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Ligand Info
Affinity DataIC50: 180nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) using (FAM)-labeled fluorescent peptide-RHKK(Ac)LM by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
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UniProtKB/SwissProt
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Ligand Info
Affinity DataIC50: 190nMAssay Description:Inhibition of human whole blood COX-2 assessed as production of PGE2 after 24 hrs by EIAMore data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) using FAM-RHKK(Ac)LM as substrate measured after 60 mins by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase II by detecting the conversion of supercoiled pBR322 DNA to its relaxed for...More data for this Ligand-Target Pair
Affinity DataIC50: 460nMAssay Description:Inhibition of human GST-fused SIRT2 expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
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Ligand Info
Affinity DataIC50: 600nMAssay Description:Inhibition of COX1 in human whole blood assessed as TXB2 biosynthesis after 24 hrs by EIAMore data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed formMore data for this Ligand-Target Pair
Affinity DataIC50: 980nMAssay Description:Inhibition of SIRT2 (unknown origin)More data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
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Ligand Info
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of human SIRT2More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) using FAM-RHKK(Ac)LM as substrate measured after 60 mins by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human whole blood COX-1 assessed as production of TXB2 after 24 hrs by EIAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as TXB2 biosynthesis after 24 hrs by EIAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human SIRT2 using Ac-peptide as substrate assessed as fluorescence intensity by microplate readerMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
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Ligand Info
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed formMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human whole blood COX-1 assessed as inhibition of TXB2 production by EIAMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Anadolu University
Curated by ChEMBL
Anadolu University
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged HER4 (682 to 993 residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 G...More data for this Ligand-Target Pair
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibition of SIRT2 (unknown origin)More data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
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Ligand Info
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed formMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) using RHKK(Ac)-MCA as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) using FAM-RHKK(Ac)LM as substrate measured after 60 mins by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Kumamoto University
Curated by ChEMBL
Kumamoto University
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of [3H]-farnesyl pyrophosphate binding to human farnesyltransferaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human whole blood COX-2 assessed as production of PGE2 after 24 hrs by EIAMore data for this Ligand-Target Pair
TargetMultidrug and toxin extrusion protein 1(Homo sapiens (Human))
Setsunan University
Curated by ChEMBL
Setsunan University
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human MATE1More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as TXB2 biosynthesis after 24 hrs by EIAMore data for this Ligand-Target Pair
TargetMultidrug and toxin extrusion protein 1(Homo sapiens (Human))
Setsunan University
Curated by ChEMBL
Setsunan University
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human MATE1More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Anadolu University
Curated by ChEMBL
Anadolu University
Curated by ChEMBL
Affinity DataIC50: 2.28E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged HER2 (676 to end residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 G...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as PGE2 biosynthesis after 24 hrs by EIAMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human whole blood COX-2 assessed as production of PGE2 after 24 hrs by EIAMore data for this Ligand-Target Pair
Affinity DataIC50: 2.47E+3nMAssay Description:Inhibition of human SIRT2 using Ac-Glu-Thr-Asp-Lys(Dec)-AMC as substrate by fluorogenic based methodMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
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UniProtKB/SwissProt
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Ligand Info
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Kumamoto University
Curated by ChEMBL
Kumamoto University
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of [3H]-farnesyl pyrophosphate binding to human farnesyltransferaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) using FAM-RHKK(Ac)LM as substrate measured after 60 mins by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Anadolu University
Curated by ChEMBL
Anadolu University
Curated by ChEMBL
Affinity DataIC50: 2.59E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged HER4 (682 to 993 residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 G...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed formMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human whole blood COX-1 assessed as inhibition of TXB2 production by EIAMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory concentration against DNA topoisomerase I activityMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as PGE2 biosynthesis after 24 hrs by EIAMore data for this Ligand-Target Pair