Affinity DataKi: 6.30nMAssay Description:Competitive inhibition of ALK5 (unknown origin) assessed as enzyme/ATP complex by Michaelis-Menten plot analysis in presence of ATPMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Competitive inhibition of ALK5 (unknown origin) by Michaelis-Menten plot analysis in presence of ATPMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
Affinity DataIC50: 0.170nMAssay Description:Inhibition of phosphodiesterase 5 of rabbit plateletsMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
Affinity DataIC50: 0.180nMAssay Description:Inhibition of phosphodiesterase 5 of rabbit plateletsMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
Affinity DataIC50: 0.280nMAssay Description:Inhibition of phosphodiesterase 5 of rabbit plateletsMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
Affinity DataIC50: 0.280nMAssay Description:Inhibition of phosphodiesterase 5 of rabbit plateletsMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
Affinity DataIC50: 0.290nMAssay Description:Inhibition of phosphodiesterase 5 of rabbit plateletsMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of phosphodiesterase 5 of rabbit plateletsMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
Affinity DataIC50: 0.320nMAssay Description:Inhibition of phosphodiesterase 5 of rabbit plateletsMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
Affinity DataIC50: 0.340nMAssay Description:Inhibition of phosphodiesterase 5 of rabbit plateletsMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
Affinity DataIC50: 0.410nMAssay Description:Inhibition of phosphodiesterase 5 of rabbit plateletsMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross Corporation Research Center
Curated by ChEMBL
Green Cross Corporation Research Center
Curated by ChEMBL
Affinity DataIC50: 0.490nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross Corporation Research Center
Curated by ChEMBL
Green Cross Corporation Research Center
Curated by ChEMBL
Affinity DataIC50: 0.490nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
Affinity DataIC50: 0.570nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in Sprague-Dawley rat cerebellum by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
Affinity DataIC50: 0.580nMAssay Description:Inhibition of phosphodiesterase 5 of rabbit plateletsMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of phosphodiesterase 5 of rabbit plateletsMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross Corporation Research Center
Curated by ChEMBL
Green Cross Corporation Research Center
Curated by ChEMBL
Affinity DataIC50: 0.797nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
Affinity DataIC50: 0.860nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in Sprague-Dawley rat cerebellum by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataIC50: 0.930nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in Sprague-Dawley rat cerebellum by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross Corporation Research Center
Curated by ChEMBL
Green Cross Corporation Research Center
Curated by ChEMBL
Affinity DataIC50: 0.934nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
Affinity DataIC50: 0.940nMAssay Description:Inhibition of phosphodiesterase 5 of rabbit plateletsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.960nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in Sprague-Dawley rat cerebellum by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
Affinity DataIC50: 1.09nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in Sprague-Dawley rat cerebellum by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of phosphodiesterase 5 of rabbit plateletsMore data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross Corporation Research Center
Curated by ChEMBL
Green Cross Corporation Research Center
Curated by ChEMBL
Affinity DataIC50: 1.18nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair