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Found 1778 with Last Name = 'parker' and Initial = 'e'
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
University Of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50185364(CHEMBL2371908 | CHEMBL415187 | Sub[-Tyr-Arg-Leu-Ar...)
Affinity DataKi:  0.0500nMAssay Description:Displacement of [125I]hPP from human NPY4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati And Va Medical Centers

Curated by ChEMBL
LigandPNGBDBM50409214(CHEMBL2110365 | GR-231118)
Affinity DataKi:  0.0700nMAssay Description:Affinity for cloned Y1 receptor using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
University Of Cincinnati

Curated by ChEMBL
LigandPNGBDBM82286(CAS_59763-91-6 | PP, human | PP,SALMON)
Affinity DataKi:  0.0700nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
University Of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50099198(CHEMBL429531 | Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly...)
Affinity DataKi:  0.0800nMAssay Description:Affinity for cloned Y4 receptor using [125I]-PP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati And Va Medical Centers

Curated by ChEMBL
LigandPNGBDBM85813(Des-AA11-18[Cys7,21,D-Lys9 (Ac), Pro34]-NPY)
Affinity DataKi:  0.200nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
University Of Cincinnati And Va Medical Centers

Curated by ChEMBL
LigandPNGBDBM50099198(CHEMBL429531 | Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly...)
Affinity DataKi:  0.230nMAssay Description:Affinity for cloned Y2 receptor using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
University Of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50409214(CHEMBL2110365 | GR-231118)
Affinity DataKi:  0.260nMAssay Description:Affinity for cloned Y4 receptor using [125I]-PP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati And Va Medical Centers

Curated by ChEMBL
LigandPNGBDBM50099197(CHEMBL411117 | Ile-Glu-Pro-Dpr-Tyr-Arg-Leu-Arg-Tyr...)
Affinity DataKi:  0.270nMAssay Description:Affinity for cloned Y1 receptor using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati And Va Medical Centers

Curated by ChEMBL
LigandPNGBDBM50015490(CHEMBL438945 | H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...)
Affinity DataKi:  0.280nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50373621(CHEMBL403414)
Affinity DataKi:  0.400nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Unc Eshelman School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50469353(CHEMBL4283353)
Affinity DataKi:  0.430nMAssay Description:Inhibition of MERTK (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati And Va Medical Centers

Curated by ChEMBL
LigandPNGBDBM50099200(CHEMBL410166 | Ile-Glu-Pro-Dpr-Tyr-Arg-Leu-Arg-(CH...)
Affinity DataKi:  0.460nMAssay Description:Affinity for cloned Y1 receptor using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati And Va Medical Centers

Curated by ChEMBL
LigandPNGBDBM50099198(CHEMBL429531 | Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly...)
Affinity DataKi:  0.520nMAssay Description:Affinity for cloned Y1 receptor using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299343((2S,4R)-1-((R)-5-chloro-1-(2,4-dimethoxyphenylsulf...)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]Arg8-vasopressin from human vasopressin V1b receptor expressed in CHO-K1 cells by Packard Topcount scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50468037(CHEMBL4293298)
Affinity DataKi:  0.700nMAssay Description:Inhibition of recombinant human BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati And Va Medical Centers

Curated by ChEMBL
LigandPNGBDBM85808(Des-AA11-18[Cys7,21,D-Lys9 (Ac)]-NPY)
Affinity DataKi:  0.700nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50468040(CHEMBL4289763)
Affinity DataKi:  0.700nMAssay Description:Inhibition of recombinant human BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50373623(CHEMBL404461)
Affinity DataKi:  0.75nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50317048(CHEMBL1097342 | N-((1S,2S)-3-(3,5-difluorophenyl)-...)
Affinity DataKi:  0.800nMAssay Description:Inhibition oh BACE1More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati And Va Medical Centers

Curated by ChEMBL
LigandPNGBDBM85815([D-Arg25]-NPY)
Affinity DataKi:  0.900nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50317056(CHEMBL1097349 | N-((1S,2S)-1-((R)-4-(3-chloropheny...)
Affinity DataKi:  1nMAssay Description:Inhibition oh BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50317055(CHEMBL1097348 | N-((1S,2S)-3-(3,5-difluorophenyl)-...)
Affinity DataKi:  1nMAssay Description:Inhibition oh BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1b receptor(RAT)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299343((2S,4R)-1-((R)-5-chloro-1-(2,4-dimethoxyphenylsulf...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]Arg8-vasopressin from rat vasopressin V1b receptor expressed in CHO-K1 cells by Packard Topcount scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50468038(CHEMBL4294236)
Affinity DataKi:  1nMAssay Description:Inhibition of recombinant human BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50468047(CHEMBL4278011)
Affinity DataKi:  1nMAssay Description:Inhibition of recombinant human BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50468046(CHEMBL4278154)
Affinity DataKi:  1nMAssay Description:Inhibition of recombinant human BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50468043(CHEMBL4288838)
Affinity DataKi:  1nMAssay Description:Inhibition of recombinant human BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50468044(CHEMBL4279084)
Affinity DataKi:  1nMAssay Description:Inhibition of recombinant human BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50164512(CHEMBL3800286)
Affinity DataKi:  1nMAssay Description:Inhibition of recombinant human BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50596254(CHEMBL5198665)
Affinity DataKi:  1nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50596252(CHEMBL5190011)
Affinity DataKi:  1nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50468039(CHEMBL4278329)
Affinity DataKi:  1nMAssay Description:Inhibition of recombinant human BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50468048(CHEMBL4280271)
Affinity DataKi:  1nMAssay Description:Inhibition of recombinant human BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50317052(CHEMBL1097346 | N-((1S,2S)-3-(3,5-difluorophenyl)-...)
Affinity DataKi:  1nMAssay Description:Inhibition oh BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50317051(CHEMBL1097345 | N-[(1S,2S)-3-(3,5-difluorophenyl)-...)
Affinity DataKi:  1nMAssay Description:Inhibition oh BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50317050(1-N-[(1S,2S)-3-(3,5-difluorophenyl)-1-hydroxy-1-[(...)
Affinity DataKi:  1nMAssay Description:Inhibition oh BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50317027(CHEMBL1097321 | N1-((1S,2S)-3-(3,5-difluorophenyl)...)
Affinity DataKi:  1nMAssay Description:Inhibition oh BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50317060(CHEMBL1097353 | N-((1S,2S)-1-((R)-4-(benzylsulfony...)
Affinity DataKi:  1nMAssay Description:Inhibition oh BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50317058(CHEMBL1097351 | N-((1S,2S)-1-((R)-4-(5-chlorothiop...)
Affinity DataKi:  1nMAssay Description:Inhibition oh BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392835(CHEMBL2151181)
Affinity DataKi: <1nMAssay Description:Inhibition of human recombinant BACE2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50398683(CHEMBL2178147)
Affinity DataKi:  1nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50398688(CHEMBL2178715)
Affinity DataKi:  1nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50373639(CHEMBL428423)
Affinity DataKi:  1.10nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
University Of Cincinnati And Va Medical Centers

Curated by ChEMBL
LigandPNGBDBM50015490(CHEMBL438945 | H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...)
Affinity DataKi:  1.20nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50373624(CHEMBL255353)
Affinity DataKi:  1.20nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Cincinnati And Va Medical Centers

Curated by ChEMBL
LigandPNGBDBM85812(Des-AA11-18[Cys7,21,D-Lys9 (Ac), D-His26, Pro34]-N...)
Affinity DataKi:  1.20nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50108680(CHEMBL3596517)
Affinity DataKi:  1.40nMAssay Description:Inhibition of human adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50164512(CHEMBL3800286)
Affinity DataKi:  1.40nMAssay Description:Inhibition of recombinant human BACE1 preincubated for 30 mins followed QSY7EISEVNLDAEFC-Eu-amide substrate addition measured after 90 mins by FRET a...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
University Of Cincinnati And Va Medical Centers

Curated by ChEMBL
LigandPNGBDBM85814(Des-AA11-18[Cys7,21,D-Lys9 (Ac), D-His26]-NPY)
Affinity DataKi:  1.40nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
University Of Cincinnati And Va Medical Centers

Curated by ChEMBL
LigandPNGBDBM85808(Des-AA11-18[Cys7,21,D-Lys9 (Ac)]-NPY)
Affinity DataKi:  1.40nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
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