Affinity DataKi: 0.0300nMAssay Description:Binding affinity for alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)
Curated by ChEMBL
Spanish National Cancer Research Centre (Cnio)
Curated by ChEMBL
Affinity DataKi: 0.0600nMAssay Description:Inhibition of human p110alpha/p85alpha using PIP2 as substrate in presence of ATP measured by HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)
Curated by ChEMBL
Spanish National Cancer Research Centre (Cnio)
Curated by ChEMBL
Affinity DataKi: 0.0600nMAssay Description:Inhibition of human p110delta/p85alpha using PIP2 as substrate in presence of ATP measured by HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)
Curated by ChEMBL
Spanish National Cancer Research Centre (Cnio)
Curated by ChEMBL
Affinity DataKi: 0.0700nMAssay Description:Inhibition of human p110delta/p85alpha using PIP2 as substrate in presence of ATP measured by HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)
Curated by ChEMBL
Spanish National Cancer Research Centre (Cnio)
Curated by ChEMBL
Affinity DataKi: 0.0800nMAssay Description:Inhibition of human PI3K p110delta/p85alpha by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Binding affinity for alpha-2A adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Binding affinity for alpha-2A adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Inhibition of [3H]- rauwolscine binding to alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Binding affinity for alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Binding affinity for alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Binding affinity for alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)
Curated by ChEMBL
Spanish National Cancer Research Centre (Cnio)
Curated by ChEMBL
Affinity DataKi: 0.100nMAssay Description:Inhibition of p110alpha H1047R mutant/p85alpha (unknown origin) using PIP2:3PS lipid kinase as substrate in presence of ATP measured by ADP-Glo lipid...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)
Curated by ChEMBL
Spanish National Cancer Research Centre (Cnio)
Curated by ChEMBL
Affinity DataKi: 0.130nMAssay Description:Inhibition of human PI3K p110delta/p85alpha by HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)
Curated by ChEMBL
Spanish National Cancer Research Centre (Cnio)
Curated by ChEMBL
Affinity DataKi: 0.160nMAssay Description:Inhibition of human p110alpha/p85alpha using PIP2 as substrate in presence of ATP measured by HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)
Curated by ChEMBL
Spanish National Cancer Research Centre (Cnio)
Curated by ChEMBL
Affinity DataKi: 0.170nMAssay Description:Inhibition of human PI3Kgamma by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:In vitro binding affinity towards human adrenergic alpha-2C adrenergic receptor using [3H]-rauwolscineMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:In vitro binding affinity to human alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:In vitro binding affinity to human alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Binding affinity for alpha-2C-adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Binding affinity for alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Agricultural Sciences and Veterinary Medicine
University of Agricultural Sciences and Veterinary Medicine
Affinity DataKi: 0.200nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Binding affinity for alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:In vitro binding affinity to human alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Inhibition of [3H]- rauwolscine binding to alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:In vitro binding affinity to human alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:In vitro binding affinity to human alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:In vitro binding affinity to human alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Binding affinity for alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Binding affinity for alpha-2A adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:In vitro binding affinity to human alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Binding affinity for alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)
Curated by ChEMBL
Spanish National Cancer Research Centre (Cnio)
Curated by ChEMBL
Affinity DataKi: 0.25nMAssay Description:Inhibition of human PI3K p110alpha/p85alpha by HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)
Curated by ChEMBL
Spanish National Cancer Research Centre (Cnio)
Curated by ChEMBL
Affinity DataKi: 0.270nMAssay Description:Inhibition of p110alpha E542K mutant/p85alpha (unknown origin) using PIP2:3PS lipid kinase as substrate in presence of ATP measured by ADP-Glo lipid ...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)
Curated by ChEMBL
Spanish National Cancer Research Centre (Cnio)
Curated by ChEMBL
Affinity DataKi: 0.270nMAssay Description:Inhibition of human PI3K p110alpha/p85alpha by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibition of [3H]- rauwolscine binding to human alpha-2A adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Ki value against human carbonic anhydrase XII (hCA XII)More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:In vitro binding affinity to the human alpha-2A adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:In vitro binding affinity to the human alpha-2A adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Binding affinity for alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:In vitro binding affinity to the human alpha-2A adrenergic receptorMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Agricultural Sciences and Veterinary Medicine
University of Agricultural Sciences and Veterinary Medicine
Affinity DataKi: 0.300nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Agricultural Sciences and Veterinary Medicine
University of Agricultural Sciences and Veterinary Medicine
Affinity DataKi: 0.300nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibition of [3H]- rauwolscine binding to human alpha-2A adrenergic receptorMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Agricultural Sciences and Veterinary Medicine
University of Agricultural Sciences and Veterinary Medicine
Affinity DataKi: 0.300nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:In vitro binding affinity to human alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:In vitro binding affinity to human alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)
Curated by ChEMBL
Spanish National Cancer Research Centre (Cnio)
Curated by ChEMBL
Affinity DataKi: 0.310nMAssay Description:Inhibition of human PI3K p110beta/p85alpha by HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)
Curated by ChEMBL
Spanish National Cancer Research Centre (Cnio)
Curated by ChEMBL
Affinity DataKi: 0.370nMAssay Description:Inhibition of human PI3K p110beta/p85alpha by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:In vitro binding affinity to human alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Binding affinity for alpha-2A adrenergic receptorMore data for this Ligand-Target Pair