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Found 47 with Last Name = 'patruno' and Initial = 'a'
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50330059((+/-)-1-[(2-Methyl-1-phenylpropyl)amino]ethanimini...)
Affinity DataIC50:  200nMAssay Description:Inhibition of rat brain nNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Università

Curated by ChEMBL
LigandPNGBDBM50292744(1-(Benzylamino)ethaniminium bromide | CHEMBL462334)
Affinity DataIC50:  200nMAssay Description:Inhibition of mouse macrophage iNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Universita G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50292744(1-(Benzylamino)ethaniminium bromide | CHEMBL462334)
Affinity DataIC50:  200nMAssay Description:Inhibition of iNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline preincubated 1 hr b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Universita G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50292746((+/-)-N-(1-Phenylpropyl)ethanimidamide hydrobromid...)
Affinity DataIC50:  250nMAssay Description:Inhibition of iNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline preincubated 1 hr b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Università

Curated by ChEMBL
LigandPNGBDBM50292746((+/-)-N-(1-Phenylpropyl)ethanimidamide hydrobromid...)
Affinity DataIC50:  250nMAssay Description:Inhibition of mouse macrophage iNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Universita G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50292749(1-[(1-Propionylpiperidin-4-yl)amino]ethaniminium b...)
Affinity DataIC50:  250nMAssay Description:Inhibition of iNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline preincubated 1 hr b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50330058(1-(Benzhydrylamino)ethaniminium bromide | CHEMBL12...)
Affinity DataIC50:  300nMAssay Description:Inhibition of rat brain nNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Universita G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50226527(CHEMBL107251 | N-(3-(AMINOMETHYL)BENZYL)ACETAMIDIN...)
Affinity DataIC50:  330nMAssay Description:Inhibition of iNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline preincubated 1 hr b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Università

Curated by ChEMBL
LigandPNGBDBM50226527(CHEMBL107251 | N-(3-(AMINOMETHYL)BENZYL)ACETAMIDIN...)
Affinity DataIC50:  330nMAssay Description:Inhibition of mouse macrophage iNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Universita G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50292747(1-[(3-{[(Pyridin-4-ylmethyl)amino]methyl}benzyl)am...)
Affinity DataIC50:  350nMAssay Description:Inhibition of iNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline preincubated 1 hr b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Universita G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50292745(1-[(1-Phenylethyl)amino]ethaniminium bromide | CHE...)
Affinity DataIC50:  450nMAssay Description:Inhibition of iNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline preincubated 1 hr b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Università

Curated by ChEMBL
LigandPNGBDBM50292745(1-[(1-Phenylethyl)amino]ethaniminium bromide | CHE...)
Affinity DataIC50:  450nMAssay Description:Inhibition of mouse macrophage iNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Universita G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50292748(1-{[3-({[(4-Methylphenyl)sulfonyl]amino}methyl)ben...)
Affinity DataIC50:  500nMAssay Description:Inhibition of iNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline preincubated 1 hr b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM7885(1-benzyl-2-methyl-1H-imidazole | US9138393, 1-benz...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of rat brain nNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50330055((+/-)-2-Methyl-1-(1-phenylethyl)-1H-imidazole | CH...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of rat brain nNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50330054(4-[(2-Methyl-1H-imidazol-1-yl)methyl]pyridine | CH...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of rat brain nNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50226527(CHEMBL107251 | N-(3-(AMINOMETHYL)BENZYL)ACETAMIDIN...)
Affinity DataIC50:  7.30E+3nMAssay Description:Inhibition of rat brain nNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Università

Curated by ChEMBL
LigandPNGBDBM50330059((+/-)-1-[(2-Methyl-1-phenylpropyl)amino]ethanimini...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of mouse macrophage iNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50330057(1-[(3-Methoxybenzyl)amino]ethaniminium chloride | ...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of rat brain nNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Università

Curated by ChEMBL
LigandPNGBDBM50330054(4-[(2-Methyl-1H-imidazol-1-yl)methyl]pyridine | CH...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of mouse macrophage iNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Universita G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50292747(1-[(3-{[(Pyridin-4-ylmethyl)amino]methyl}benzyl)am...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of eNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline preincubated 1 hr b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Università

Curated by ChEMBL
LigandPNGBDBM50330058(1-(Benzhydrylamino)ethaniminium bromide | CHEMBL12...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of mouse macrophage iNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Università

Curated by ChEMBL
LigandPNGBDBM7885(1-benzyl-2-methyl-1H-imidazole | US9138393, 1-benz...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of mouse macrophage iNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Università

Curated by ChEMBL
LigandPNGBDBM50330057(1-[(3-Methoxybenzyl)amino]ethaniminium chloride | ...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of mouse macrophage iNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Universita G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50292746((+/-)-N-(1-Phenylpropyl)ethanimidamide hydrobromid...)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibition of eNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline preincubated 1 hr b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Università

Curated by ChEMBL
LigandPNGBDBM50292746((+/-)-N-(1-Phenylpropyl)ethanimidamide hydrobromid...)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibition of bovine eNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Università

Curated by ChEMBL
LigandPNGBDBM50330055((+/-)-2-Methyl-1-(1-phenylethyl)-1H-imidazole | CH...)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibition of bovine eNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Universita G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50292749(1-[(1-Propionylpiperidin-4-yl)amino]ethaniminium b...)
Affinity DataIC50:  9.00E+4nMAssay Description:Inhibition of eNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline preincubated 1 hr b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Università

Curated by ChEMBL
LigandPNGBDBM7885(1-benzyl-2-methyl-1H-imidazole | US9138393, 1-benz...)
Affinity DataIC50:  9.00E+4nMAssay Description:Inhibition of bovine eNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50292746((+/-)-N-(1-Phenylpropyl)ethanimidamide hydrobromid...)
Affinity DataIC50:  9.00E+4nMAssay Description:Inhibition of rat brain nNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Università

Curated by ChEMBL
LigandPNGBDBM50330054(4-[(2-Methyl-1H-imidazol-1-yl)methyl]pyridine | CH...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of bovine eNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Università

Curated by ChEMBL
LigandPNGBDBM50330059((+/-)-1-[(2-Methyl-1-phenylpropyl)amino]ethanimini...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of bovine eNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Università

Curated by ChEMBL
LigandPNGBDBM50330055((+/-)-2-Methyl-1-(1-phenylethyl)-1H-imidazole | CH...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of mouse macrophage iNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Università

Curated by ChEMBL
LigandPNGBDBM50330057(1-[(3-Methoxybenzyl)amino]ethaniminium chloride | ...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of bovine eNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50292745(1-[(1-Phenylethyl)amino]ethaniminium bromide | CHE...)
Affinity DataIC50:  1.50E+5nMAssay Description:Inhibition of rat brain nNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50292744(1-(Benzylamino)ethaniminium bromide | CHEMBL462334)
Affinity DataIC50:  1.50E+5nMAssay Description:Inhibition of rat brain nNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Universita G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50292745(1-[(1-Phenylethyl)amino]ethaniminium bromide | CHE...)
Affinity DataIC50:  3.00E+5nMAssay Description:Inhibition of eNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline preincubated 1 hr b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Università

Curated by ChEMBL
LigandPNGBDBM50292745(1-[(1-Phenylethyl)amino]ethaniminium bromide | CHE...)
Affinity DataIC50:  3.00E+5nMAssay Description:Inhibition of bovine eNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Universita G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50292748(1-{[3-({[(4-Methylphenyl)sulfonyl]amino}methyl)ben...)
Affinity DataIC50:  3.00E+5nMAssay Description:Inhibition of eNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline preincubated 1 hr b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Universita G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50292744(1-(Benzylamino)ethaniminium bromide | CHEMBL462334)
Affinity DataIC50:  3.50E+5nMAssay Description:Inhibition of eNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline preincubated 1 hr b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Università

Curated by ChEMBL
LigandPNGBDBM50330058(1-(Benzhydrylamino)ethaniminium bromide | CHEMBL12...)
Affinity DataIC50:  3.50E+5nMAssay Description:Inhibition of bovine eNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Università

Curated by ChEMBL
LigandPNGBDBM50292744(1-(Benzylamino)ethaniminium bromide | CHEMBL462334)
Affinity DataIC50:  3.50E+5nMAssay Description:Inhibition of bovine eNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Università

Curated by ChEMBL
LigandPNGBDBM50330056(1-[(1,3-Benzodioxol-5-ylmethyl)amino]ethaniminium ...)
Affinity DataIC50:  4.00E+5nMAssay Description:Inhibition of bovine eNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50330056(1-[(1,3-Benzodioxol-5-ylmethyl)amino]ethaniminium ...)
Affinity DataIC50:  4.00E+5nMAssay Description:Inhibition of rat brain nNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Università

Curated by ChEMBL
LigandPNGBDBM50330056(1-[(1,3-Benzodioxol-5-ylmethyl)amino]ethaniminium ...)
Affinity DataIC50:  8.00E+5nMAssay Description:Inhibition of mouse macrophage iNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Università

Curated by ChEMBL
LigandPNGBDBM50226527(CHEMBL107251 | N-(3-(AMINOMETHYL)BENZYL)ACETAMIDIN...)
Affinity DataIC50:  1.10E+6nMAssay Description:Inhibition of bovine eNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Universita G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50226527(CHEMBL107251 | N-(3-(AMINOMETHYL)BENZYL)ACETAMIDIN...)
Affinity DataIC50:  1.10E+6nMAssay Description:Inhibition of eNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline preincubated 1 hr b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed