Compile Data Set for Download or QSAR
maximum 50k data
Found 133 with Last Name = 'perron' and Initial = 'dc'
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  19nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305013(3-(2-amino-7-(7-(benzo[b]thiophen-2-yl)-1H-indazol...)
Affinity DataIC50:  20nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  33nMAssay Description:Inhibition of IKK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305007(5-(3-aminopropyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-...)
Affinity DataIC50:  35nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305010(3-(2-amino-7-(7-(benzo[b]thiophen-2-yl)-1H-indazol...)
Affinity DataIC50:  37nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305014(3-(2-amino-7-(7-(benzo[b]thiophen-2-yl)-1H-indazol...)
Affinity DataIC50:  41nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  44nMAssay Description:Inhibition of CHK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  53nMAssay Description:Inhibition of pdk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305003(7-(7-(benzo[b]thiophen-2-yl)-1H-indazol-5-yl)-5H-p...)
Affinity DataIC50:  56nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C eta type(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  98nMAssay Description:Inhibition of PKCetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine-1-phosphate lyase 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50500988(CHEMBL3798814)
Affinity DataIC50:  117nMAssay Description:Inhibition of human sphingosine 1-phosphate lyase after 22 hrs by umbelliferone fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  140nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine-1-phosphate lyase 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50500982(CHEMBL3798147)
Affinity DataIC50:  150nMAssay Description:Inhibition of human sphingosine 1-phosphate lyase after 22 hrs by umbelliferone fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetSphingosine-1-phosphate lyase 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50500974(CHEMBL3799061)
Affinity DataIC50:  150nMAssay Description:Inhibition of human sphingosine 1-phosphate lyase after 22 hrs by umbelliferone fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305001(CHEMBL592288 | N4-(3-(1H-pyrrol-2-yl)-1H-indazol-5...)
Affinity DataIC50:  160nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305000(CHEMBL600081 | N4-(3-(benzo[b]thiophen-2-yl)-1H-in...)
Affinity DataIC50:  160nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  170nMAssay Description:Inhibition of GSK3alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP/microtubule affinity-regulating kinase 3(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  210nMAssay Description:Inhibition of CTAK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine-1-phosphate lyase 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50500988(CHEMBL3798814)
Affinity DataIC50:  230nMAssay Description:Inhibition of wild-type full-length human sphingosine 1-phosphate lyase transfected in HEK293-H cells preincubated for 30 mins followed by addition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  230nMAssay Description:Inhibition of CDK5/P25More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine-1-phosphate lyase 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50500983(CHEMBL3798874)
Affinity DataIC50:  240nMAssay Description:Inhibition of wild-type full-length human sphingosine 1-phosphate lyase transfected in HEK293-H cells preincubated for 30 mins followed by addition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305008(5-(4-aminobutyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  260nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine-1-phosphate lyase 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50500975(CHEMBL3799085)
Affinity DataIC50:  260nMAssay Description:Inhibition of human sphingosine 1-phosphate lyase after 22 hrs by umbelliferone fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50304999(CHEMBL590834 | N4-(3-(naphthalen-2-yl)-1H-indazol-...)
Affinity DataIC50:  310nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  320nMAssay Description:Inhibition of CDC2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  380nMAssay Description:Inhibition of PLK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  400nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  440nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  440nMAssay Description:Inhibition of DYRK1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine-1-phosphate lyase 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50500979(CHEMBL3798254)
Affinity DataIC50:  485nMAssay Description:Inhibition of human sphingosine 1-phosphate lyase after 22 hrs by umbelliferone fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305016(7-(7-(benzo[b]thiophen-2-yl)-1H-indazol-5-yl)-5-is...)
Affinity DataIC50:  490nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  510nMAssay Description:Inhibition of PAK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  530nMAssay Description:Inhibition of Ck1deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  570nMAssay Description:Inhibition of MST2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine-1-phosphate lyase 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50500983(CHEMBL3798874)
Affinity DataIC50:  590nMAssay Description:Inhibition of human sphingosine 1-phosphate lyase after 22 hrs by umbelliferone fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  690nMAssay Description:Inhibition of SGKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine-1-phosphate lyase 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50500986(CHEMBL3797779)
Affinity DataIC50:  720nMAssay Description:Inhibition of human sphingosine 1-phosphate lyase after 22 hrs by umbelliferone fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50304994(CHEMBL589650 | N4-(7-(naphthalen-2-yl)-1H-indazol-...)
Affinity DataIC50:  720nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine-1-phosphate lyase 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50500980(CHEMBL3798062)
Affinity DataIC50:  730nMAssay Description:Inhibition of human sphingosine 1-phosphate lyase after 22 hrs by umbelliferone fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305011(7-(7-(benzo[b]thiophen-2-yl)-1H-indazol-5-yl)-5-(3...)
Affinity DataIC50:  820nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine-1-phosphate lyase 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50500981(CHEMBL3799254)
Affinity DataIC50:  850nMAssay Description:Inhibition of human sphingosine 1-phosphate lyase after 22 hrs by umbelliferone fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  860nMAssay Description:Inhibition of PKCdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine-1-phosphate lyase 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50500975(CHEMBL3799085)
Affinity DataIC50:  930nMAssay Description:Inhibition of wild-type full-length human sphingosine 1-phosphate lyase transfected in HEK293-H cells preincubated for 30 mins followed by addition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  940nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  950nMAssay Description:Inhibition of PKD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305009(7-(7-(benzo[b]thiophen-2-yl)-1H-indazol-5-yl)-5-(2...)
Affinity DataIC50:  960nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine-1-phosphate lyase 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50500984(CHEMBL3799908)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human sphingosine 1-phosphate lyase after 22 hrs by umbelliferone fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetSphingosine-1-phosphate lyase 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50500976(CHEMBL3798106)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human sphingosine 1-phosphate lyase after 22 hrs by umbelliferone fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305006(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of AKT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 133 total ) | Next | Last >>
Jump to: