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Found 15 with Last Name = 'plugis' and Initial = 'nm'
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50342583((E)-4-chloro-3-(2-(2-methoxyphenyl)-2-oxoethyliden...)
Affinity DataKi:  3.30E+3nMAssay Description:Non-competitive inhibition of recombinant human TG2 V224 mutant deamidation activity using Cbz-Gln-Gly as substrate preincubated for 30 mins followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50342590((E)-4-chloro-3-(2-oxo-2-(pyridin-3-yl)ethylidene)-...)
Affinity DataKi:  9.10E+3nMAssay Description:Non-competitive inhibition of recombinant human TG2 V224 mutant deamidation activity using Cbz-Gln-Gly as substrate preincubated for 30 mins followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM81791(Dopamine + GPP(NH)p | GPP(NH)P(+) | GPP(NH)p(-) | ...)
Affinity DataKi:  2.70E+4nMAssay Description:Competitive inhibition of recombinant human TG2 V224 mutant deamidation activity using Cbz-Gln-Gly as substrate preincubated for 30 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50342582((E)-4-chloro-3-(2-(4-chlorophenyl)-2-oxoethylidene...)
Affinity DataKi:  4.70E+4nMAssay Description:Non-competitive inhibition of recombinant human TG2 V224 mutant deamidation activity using Cbz-Gln-Gly as substrate preincubated for 30 mins followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50342569((E)-3-(2-oxo-2-(pyridin-3-yl)ethylidene)indolin-2-...)
Affinity DataKi:  8.60E+4nMAssay Description:Non-competitive inhibition of recombinant human TG2 V224 mutant deamidation activity using Cbz-Gln-Gly as substrate preincubated for 30 mins followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50426066(CHEMBL2315295)
Affinity DataIC50:  90nMAssay Description:Inhibition of human recombinant thioredoxin-mediated TG2 activation expressed in T84 cells assessed as blockade of 5-biotinamidopentylamine incorpora...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50426067(CHEMBL2315297)
Affinity DataIC50:  170nMAssay Description:Inhibition of human recombinant thioredoxin-mediated TG2 activation expressed in T84 cells assessed as blockade of 5-biotinamidopentylamine incorpora...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50426065(CHEMBL2315294)
Affinity DataIC50:  240nMAssay Description:Inhibition of human recombinant thioredoxin-mediated TG2 activation expressed in T84 cells assessed as blockade of 5-biotinamidopentylamine incorpora...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50426064(CHEMBL2315292)
Affinity DataIC50:  290nMAssay Description:Inhibition of human recombinant thioredoxin-mediated TG2 activation expressed in T84 cells assessed as blockade of 5-biotinamidopentylamine incorpora...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50426070(CHEMBL2315306)
Affinity DataIC50:  340nMAssay Description:Inhibition of human recombinant thioredoxin-mediated TG2 activation expressed in T84 cells assessed as blockade of 5-biotinamidopentylamine incorpora...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50426063(CHEMBL2315290)
Affinity DataIC50:  450nMAssay Description:Inhibition of human recombinant thioredoxin-mediated TG2 activation expressed in T84 cells assessed as blockade of 5-biotinamidopentylamine incorpora...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50426068(2-(Cyclohexyldisulfanyl)Benzo[D]Thiazole | CHEMBL2...)
Affinity DataIC50:  510nMAssay Description:Inhibition of human recombinant thioredoxin-mediated TG2 activation expressed in T84 cells assessed as blockade of 5-biotinamidopentylamine incorpora...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50426062(CHEMBL2315288)
Affinity DataIC50:  540nMAssay Description:Inhibition of human recombinant thioredoxin-mediated TG2 activation expressed in T84 cells assessed as blockade of 5-biotinamidopentylamine incorpora...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50426071(CHEMBL406050 | PX-12 | US9018255, PX-12 | med.2172...)
Affinity DataIC50:  2.11E+3nMAssay Description:Inhibition of human recombinant thioredoxin-mediated TG2 activation expressed in T84 cells assessed as blockade of 5-biotinamidopentylamine incorpora...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50426069(CHEMBL2315305)
Affinity DataIC50:  7.31E+3nMAssay Description:Inhibition of human recombinant thioredoxin-mediated TG2 activation expressed in T84 cells assessed as blockade of 5-biotinamidopentylamine incorpora...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed