BindingDB PrimarySearch_ki

Found 196 with Last Name = 'pogoryelov' and Initial = 'd'

Leukotriene A-4 hydrolase(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50116538(3-{[3-(4-Benzyl-phenoxy)-propyl]-methyl-amino}-pro...)

Ki: 3nMAssay Description:Non-competitive inhibition of human C-terminal his6-tagged/N-terminal T7 gene leader sequence-tagged LTA4H using varying levels of L-arginine-7-amino...More data for this Ligand-Target Pair

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3D Structure (crystal)

Leukotriene A-4 hydrolase(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50197085(CHEMBL3921982)

Ki: 160nMAssay Description:Competitive inhibition of human C-terminal his6-tagged/N-terminal T7 gene leader sequence-tagged LTA4H using varying levels of L-arginine-7-amino-4-M...More data for this Ligand-Target Pair

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3D Structure (crystal)

Beta-1 adrenergic receptor(Homo sapiens (Human))
Goethe-University Of Frankfurt

Curated by ChEMBL

PNG

BDBM50502344(Talinolol)

Ki: 240nMAssay Description:Binding affinity to beta1 adrenergic receptor (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair

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Leukotriene A-4 hydrolase(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)

Ki: 320nMAssay Description:Competitive inhibition of human C-terminal his6-tagged/N-terminal T7 gene leader sequence-tagged LTA4H using varying levels of L-arginine-7-amino-4-M...More data for this Ligand-Target Pair

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3D Structure (crystal)

Leukotriene A-4 hydrolase(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50197084(CHEMBL3883608)

Ki: 360nMAssay Description:Competitive inhibition of human C-terminal his6-tagged/N-terminal T7 gene leader sequence-tagged LTA4H using varying levels of L-arginine-7-amino-4-M...More data for this Ligand-Target Pair

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3D Structure (crystal)

Beta-2 adrenergic receptor(Homo sapiens (Human))
Goethe-University Of Frankfurt

Curated by ChEMBL

PNG

BDBM50502344(Talinolol)

Ki: 900nMAssay Description:Binding affinity to beta2 adrenergic receptor (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair

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Leukotriene A-4 hydrolase(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM21642((2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolid...)

Ki: 3.70E+3nMAssay Description:Competitive inhibition of human C-terminal his6-tagged/N-terminal T7 gene leader sequence-tagged LTA4H using varying levels of L-arginine-7-amino-4-M...More data for this Ligand-Target Pair

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3D Structure (crystal)

Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50530480(CHEMBL4445524)

Ki: 4.80E+3nMAssay Description:Competitive inhibition of full length human soluble epoxide hydrolase pre-incubated for 30 mins before DiFMUP substrate addition by fluorescence base...More data for this Ligand-Target Pair

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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50530480(CHEMBL4445524)

Ki: 4.80E+3nMAssay Description:Competitive inhibition of full length human soluble epoxide hydrolase pre-incubated for 30 mins before DiFMUP substrate addition by fluorescence base...More data for this Ligand-Target Pair

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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50264106(CHEMBL3818875)

IC50: 0.700nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair

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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50561492(CHEMBL4800490)

IC50: 1.20nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair

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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50561490(CHEMBL4746942)

IC50: 1.60nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair

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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50561483(CHEMBL4795110)

IC50: 2nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair

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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50561482(CHEMBL4764099)

IC50: 2nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair

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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50561486(CHEMBL4759111)

IC50: 2nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair

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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50561489(CHEMBL4745687)

IC50: 2.10nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair

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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50561488(CHEMBL4745452)

IC50: 2.40nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair

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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50561491(CHEMBL4755533)

IC50: 2.40nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair

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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50561484(CHEMBL4778283)

IC50: 2.70nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair

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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50561494(CHEMBL4751593)

IC50: 3nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair

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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50561495(CHEMBL4794423)

IC50: 3nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair

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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50561487(CHEMBL4759652)

IC50: 3nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair

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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50561480(CHEMBL4791222)

IC50: 4nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair

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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50561474(CHEMBL4746544)

IC50: 5nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50561493(CHEMBL4747688)

IC50: 5nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Leukotriene A-4 hydrolase(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50116538(3-{[3-(4-Benzyl-phenoxy)-propyl]-methyl-amino}-pro...)

IC50: 6nMAssay Description:Inhibition of human C-terminal his6-tagged/N-terminal T7 gene leader sequence-tagged LTA4H using L-arginine-7-amino-4-Methylcoumarine as substrate pr...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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3D Structure (crystal)

Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50561485(CHEMBL4757630)

IC50: 7nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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3D Structure (crystal)

Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50561473(CHEMBL4753882)

IC50: 11nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50561472(CHEMBL4797528)

IC50: 12nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50561478(CHEMBL4741953)

IC50: 16nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair

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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50561471(CHEMBL4781282)

IC50: 22nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair

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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50561481(CHEMBL4746074)

IC50: 29nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair

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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50561479(CHEMBL4782144)

IC50: 40nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50561468(CHEMBL4745567)

IC50: 50nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair

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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50561470(CHEMBL4763763)

IC50: 60nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair

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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50561469(CHEMBL4754077)

IC50: 60nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Leukotriene A-4 hydrolase(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50197085(CHEMBL3921982)

IC50: 60nMAssay Description:Inhibition of human C-terminal his6-tagged/N-terminal T7 gene leader sequence-tagged LTA4H using L-arginine-7-amino-4-Methylcoumarine as substrate pr...More data for this Ligand-Target Pair

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3D Structure (crystal)

Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50502345(CHEMBL4566250)

IC50: 77nMAssay Description:Inhibition of recombinant human full length soluble epoxide hydrolase (1 to 555 residues) expressed in Escherichia coli BL21(DE3) using non-fluoresce...More data for this Ligand-Target Pair

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3D Structure (crystal)

Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Goethe-University Of Frankfurt

Curated by ChEMBL

PNG

BDBM50029781((R)-(+)-N-{3-[5-(4-fluorobenzyl)thien-2-yl]-1-meth...)

IC50: 90nMAssay Description:Inhibition of 5-LOX (unknown origin) expressed in Escherichia coli BL21-(DE3) pre-incubated for 15 mins before AA substrate addition and measured aft...More data for this Ligand-Target Pair

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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50561464(CHEMBL4793032)

IC50: 90nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Goethe-University Of Frankfurt

Curated by ChEMBL

PNG

BDBM50561489(CHEMBL4745687)

IC50: 96nMAssay Description:Inhibition of 5-LOX (unknown origin) expressed in Escherichia coli BL21-(DE3) pre-incubated for 15 mins before AA substrate addition and measured aft...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50511334(CHEMBL4557553)

IC50: 100nMAssay Description:Inhibition of full length human soluble epoxide hydrolase (1 to 555 residues) expressed in Escherichia coli BL21(DE3) using non-fluorescent PHOME as ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Goethe-University Of Frankfurt

Curated by ChEMBL

PNG

BDBM50561493(CHEMBL4747688)

IC50: 110nMAssay Description:Inhibition of 5-LOX (unknown origin) expressed in Escherichia coli BL21-(DE3) pre-incubated for 15 mins before AA substrate addition and measured aft...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Prostaglandin G/H synthase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50002861(3-(4,5-Diphenyl-oxazol-2-yl)-propionic acid | CHEM...)

IC50: 110nMAssay Description:Inhibition of COX2 in LPS-stimulated human monocytes assessed as reduction in PGE2 production by LC-tandem MIS analysisMore data for this Ligand-Target Pair

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Prostaglandin G/H synthase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM50002861(3-(4,5-Diphenyl-oxazol-2-yl)-propionic acid | CHEM...)

IC50: 110nMAssay Description:Inhibition of COX2 in LPS-stimulated human monocytes assessed as reduction in PGE2 production by LC-tandem MIS analysisMore data for this Ligand-Target Pair

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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM34233(2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-ben...)

IC50: 110nMAssay Description:Inhibition of hexa-His-tagged human soluble epoxide hydrolase C-terminal hydrolase domain expressed in Escherichia coli BL21(DE3) pre-incubated for 3...More data for this Ligand-Target Pair

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Bifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL

PNG

BDBM34233(2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-ben...)

IC50: 110nMAssay Description:Inhibition of hexa-His-tagged human soluble epoxide hydrolase C-terminal hydrolase domain expressed in Escherichia coli BL21(DE3) pre-incubated for 3...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Goethe-University Of Frankfurt

Curated by ChEMBL

PNG

BDBM50561485(CHEMBL4757630)

IC50: 110nMAssay Description:Inhibition of 5-LOX (unknown origin) expressed in Escherichia coli BL21-(DE3) pre-incubated for 15 mins before AA substrate addition and measured aft...More data for this Ligand-Target Pair

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Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Goethe-University Of Frankfurt

Curated by ChEMBL

PNG

BDBM50561492(CHEMBL4800490)

IC50: 110nMAssay Description:Inhibition of 5-LOX (unknown origin) expressed in Escherichia coli BL21-(DE3) pre-incubated for 15 mins before AA substrate addition and measured aft...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Goethe-University Of Frankfurt

Curated by ChEMBL

PNG

BDBM50561486(CHEMBL4759111)

IC50: 120nMAssay Description:Inhibition of 5-LOX (unknown origin) expressed in Escherichia coli BL21-(DE3) pre-incubated for 15 mins before AA substrate addition and measured aft...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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