Compile Data Set for Download or QSAR
maximum 50k data
Found 1167 with Last Name = 'powers' and Initial = 'd'
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50146490(3-(S)-Benzo[1,3]dioxol-5-yl-3-({(R)-5-oxo-1-[3-(1,...)
Affinity DataKi:  0.100nMAssay Description:Binding affinity towards vitronectin receptor (AlphaV-beta3 integrin).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253105(6-Chloro-N-cyclopropyl-7-(1-((S)-3-methylmorpholin...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of human recombinant GST-tagged p38alphaMAPK-induced ATF2 phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253148(CHEMBL522689 | N-(S)-sec-Butyl-6-(6-methyl-3-(meth...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of human recombinant GST-tagged p38alphaMAPK-induced ATF2 phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253150(CHEMBL493496 | N,6-Dimethyl-7-(1-((R)-3-methylmorp...)
Affinity DataKi:  0.300nMAssay Description:Inhibition of human recombinant GST-tagged p38alphaMAPK-induced ATF2 phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252776(CHEMBL495493 | N-Ethyl-6-methyl-7-(1-((S)-3-methyl...)
Affinity DataKi:  0.300nMAssay Description:Inhibition of human recombinant GST-tagged p38alphaMAPK-induced ATF2 phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253102(6-Methyl-7-(1-((S)-3-methylmorpholino)phthalazin-6...)
Affinity DataKi:  0.300nMAssay Description:Inhibition of human recombinant GST-tagged p38alphaMAPK-induced ATF2 phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253103(7-(1-Isopropoxyphthalazin-6-yl)-N,6-dimethylbenzo[...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of human recombinant GST-tagged p38alphaMAPK-induced ATF2 phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252735(CHEMBL495084 | N-Cyclopropyl-6-methyl-7-(1-o-tolyl...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of human recombinant GST-tagged p38alphaMAPK-induced ATF2 phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252777(CHEMBL523374 | N,6-Dimethyl-7-(1-((S)-3-methylmorp...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of human recombinant GST-tagged p38alphaMAPK-induced ATF2 phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253149(6-Chloro-N-isopropyl-7-(1-((S)-3-methylmorpholino)...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of human recombinant GST-tagged p38alphaMAPK-induced ATF2 phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252775(6-(3-(cyclopropylamino)-6-methylbenzo[d]isoxazol-7...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of human recombinant GST-tagged p38alphaMAPK-induced ATF2 phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50146492(3-Benzo[1,3]dioxol-5-yl-3-({1-[2-fluoro-5-(1,4,5,6...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity towards vitronectin receptor (AlphaV-beta3 integrin).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253147(CHEMBL494305 | N-Isopropyl-6-(6-methyl-3-(methylam...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of human recombinant GST-tagged p38alphaMAPK-induced ATF2 phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253104(CHEMBL521860 | N-(6-Methyl-7-(1-((S)-3-methylmorph...)
Affinity DataKi:  0.600nMAssay Description:Inhibition of human recombinant GST-tagged p38alphaMAPK-induced ATF2 phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252736(CHEMBL522877 | N-Cyclopropyl-6-methyl-7-(1-((S)-3-...)
Affinity DataKi:  0.700nMAssay Description:Inhibition of human recombinant GST-tagged p38alphaMAPK-induced ATF2 phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50146497(3-Benzo[1,3]dioxol-5-yl-3-({5-oxo-1-[3-(1,4,5,6-te...)
Affinity DataKi:  0.700nMAssay Description:Affinity for alphaIIb-beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252774(1-((S)-4-(6-(3-(Cyclopropylamino)-6-methylbenzo[d]...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of human recombinant GST-tagged p38alphaMAPK-induced ATF2 phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253101(7-(1-Isopropylphthalazin-6-yl)-N,6-dimethylbenzo[d...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of human recombinant GST-tagged p38alphaMAPK-induced ATF2 phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50146493(3-({5-Oxo-1-[3-(1,4,5,6-tetrahydro-pyrimidin-2-yla...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity towards vitronectin receptor (AlphaV-beta3 integrin).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252777(CHEMBL523374 | N,6-Dimethyl-7-(1-((S)-3-methylmorp...)
Affinity DataKi:  1.80nMAssay Description:Inhibition of human recombinant GST-tagged p38beta-induced ATF2 phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252738(6-Methyl-7-(1-((S)-3-methylmorpholino)phthalazin-6...)
Affinity DataKi:  2nMAssay Description:Inhibition of human recombinant GST-tagged p38alphaMAPK-induced ATF2 phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50146481(3-Benzo[1,3]dioxol-5-yl-3-({1-[3-(3-benzyl-ureido)...)
Affinity DataKi:  2.40nMAssay Description:Binding affinity towards vitronectin receptor (AlphaV-beta3 integrin).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50146488(3-{[1-(2-Fluoro-5-guanidino-phenyl)-5-oxo-pyrrolid...)
Affinity DataKi:  2.90nMAssay Description:Affinity for alphaIIb-beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265490(CHEMBL501238 | N-{m-[R(+)-1]Ureaphenoxy}ethyldigly...)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H]DAMGO from CCK2R-MOPR (unknown origin) coexpressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50146482(3-({1-[3-(4,5-Dihydro-1H-imidazol-2-ylamino)-pheny...)
Affinity DataKi:  5.10nMAssay Description:Affinity for alphaIIb-beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265491(1-{1-Diglycoldiamide-2-[m-(R(+)-1)ureaphenoxy]etha...)
Affinity DataKi:  5.70nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM21015((2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  6.70nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265491(1-{1-Diglycoldiamide-2-[m-(R(+)-1)ureaphenoxy]etha...)
Affinity DataKi:  7.30nMAssay Description:Displacement of [3H]DAMGO from CCK2R-MOPR (unknown origin) coexpressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50146485(3-(R)-Benzo[1,3]dioxol-5-yl-3-({(R)-5-oxo-1-[3-(1,...)
Affinity DataKi:  7.30nMAssay Description:Binding affinity towards vitronectin receptor (AlphaV-beta3 integrin).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265490(CHEMBL501238 | N-{m-[R(+)-1]Ureaphenoxy}ethyldigly...)
Affinity DataKi:  8.30nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50146496((S)-3-({(R)-1-[3-(3-Benzyl-ureido)-phenyl]-5-oxo-p...)
Affinity DataKi:  10nMAssay Description:Affinity for alphaIIb-beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50146495(3-({1-[3-(3-Benzyl-ureido)-phenyl]-5-oxo-pyrrolidi...)
Affinity DataKi:  10nMAssay Description:Affinity for alphaIIb-beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50146484(3-({1-[3-(3-Benzyl-ureido)-phenyl]-5-oxo-pyrrolidi...)
Affinity DataKi:  11nMAssay Description:Binding affinity towards vitronectin receptor (AlphaV-beta3 integrin).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM21015((2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]DAMGO from CCK2R-MOPR (unknown origin) coexpressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50006878((R)-1-(1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benz...)
Affinity DataKi:  14nMAssay Description:Displacement of [125I]CCK-26-33 from CCK2R-MOPR (unknown origin) coexpressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265493(CHEMBL442943 | N-{m-[R(+)-1]Ureaphenoxy}ethyl-N'-o...)
Affinity DataKi:  14.2nMAssay Description:Displacement of [3H]DAMGO from CCK2R-MOPR (unknown origin) coexpressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253151(6-Methyl-7-(1-((S)-3-methylmorpholino)phthalazin-6...)
Affinity DataKi:  16nMAssay Description:Inhibition of human recombinant GST-tagged p38alphaMAPK-induced ATF2 phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265492(1-{1-Diglycoldiamide-6-[m-(R(+)-1)ureaphenoxy]etha...)
Affinity DataKi:  16.3nMAssay Description:Displacement of [3H]DAMGO from CCK2R-MOPR (unknown origin) coexpressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50146489(3-{[1-(3-Guanidino-phenyl)-5-oxo-pyrrolidine-3-car...)
Affinity DataKi:  17nMAssay Description:Binding affinity towards vitronectin receptor (AlphaV-beta3 integrin).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50006878((R)-1-(1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benz...)
Affinity DataKi:  18nMAssay Description:Displacement of [125I]CCK-26-33 from CCK2 receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265494((R)-N-methyl-2-(1-(3-(3-(1-methyl-2-oxo-5-phenyl-2...)
Affinity DataKi:  21nMAssay Description:Displacement of [125I]CCK-26-33 from CCK2R-MOPR (unknown origin) coexpressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265493(CHEMBL442943 | N-{m-[R(+)-1]Ureaphenoxy}ethyl-N'-o...)
Affinity DataKi:  24.1nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265492(1-{1-Diglycoldiamide-6-[m-(R(+)-1)ureaphenoxy]etha...)
Affinity DataKi:  29.4nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265533(2-({[(1S,5R,13R,14S,17S)-9,17-dihydroxy-4-methyl-1...)
Affinity DataKi:  29.8nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265491(1-{1-Diglycoldiamide-2-[m-(R(+)-1)ureaphenoxy]etha...)
Affinity DataKi:  33nMAssay Description:Displacement of [125I]CCK-26-33 from CCK2R-MOPR (unknown origin) coexpressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265533(2-({[(1S,5R,13R,14S,17S)-9,17-dihydroxy-4-methyl-1...)
Affinity DataKi:  40.7nMAssay Description:Displacement of [3H]DAMGO from CCK2R-MOPR (unknown origin) coexpressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265494((R)-N-methyl-2-(1-(3-(3-(1-methyl-2-oxo-5-phenyl-2...)
Affinity DataKi:  48nMAssay Description:Displacement of [125I]CCK-26-33 from CCK2 receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50146494(3-{[1-(2-Chloro-5-guanidino-phenyl)-5-oxo-pyrrolid...)
Affinity DataKi:  53nMAssay Description:Binding affinity towards vitronectin receptor (AlphaV-beta3 integrin).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50265490(CHEMBL501238 | N-{m-[R(+)-1]Ureaphenoxy}ethyldigly...)
Affinity DataKi:  57nMAssay Description:Displacement of [125I]CCK-26-33 from CCK2R-MOPR (unknown origin) coexpressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50146491(3-({1-[3-(3-Benzyl-ureido)-phenyl]-5-oxo-pyrrolidi...)
Affinity DataKi:  71nMAssay Description:Binding affinity towards vitronectin receptor (AlphaV-beta3 integrin).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 1167 total ) | Next | Last >>
Jump to: