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Found 21 with Last Name = 'prokoph' and Initial = 'n'
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50586288(CHEMBL5070753)
Affinity DataIC50:  24nMAssay Description:Binding affinity to PPARgamma (unknown origin) by lanthascreen TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50030474(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
Affinity DataIC50:  90nMAssay Description:Binding affinity to PPARgamma (unknown origin) by lanthascreen TR-FRET assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM147253(US8957093, 73)
Affinity DataIC50:  154nMAssay Description:Binding affinity to PPARgamma (unknown origin) by lanthascreen TR-FRET assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50586288(CHEMBL5070753)
Affinity DataIC50:  160nMAssay Description:Inhibition of PPARgamma (unknown origin) phosphorylation at pS273 residueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM147253(US8957093, 73)
Affinity DataIC50:  580nMAssay Description:Inhibition of PPARgamma (unknown origin) phosphorylation at pS273 residueMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50030474(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of PPARgamma (unknown origin) phosphorylation at pS273 residueMore data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50586288(CHEMBL5070753)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of recombinant human CYP2C9 preincubated for 10 mins followed by NADPH addition and measured at 20 to 50 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor SOX-18(Mus musculus (Mouse))
The University of Queensland

LigandPNGBDBM223293(Sm4 | US20240002326, Compound Sm4)
Affinity DataIC50:  9.75E+4nMpH: 7.5 T: 2°CAssay Description:The DNA-binding competition assay was performed in 25 μL, in black 384-well plates, using either 30 mM HEPES (N-2-Hydroxyethylpiperazine-N'-2-Etha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor SOX-18(Mus musculus (Mouse))
The University of Queensland

LigandPNGBDBM223299(Sm14 | US20240002326, Compound Sm14)
Affinity DataIC50:  1.20E+5nMpH: 7.5 T: 2°CAssay Description:The DNA-binding competition assay was performed in 25 μL, in black 384-well plates, using either 30 mM HEPES (N-2-Hydroxyethylpiperazine-N'-2-Etha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor SOX-18(Mus musculus (Mouse))
The University of Queensland

LigandPNGBDBM22971(2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid...)
Affinity DataIC50:  1.63E+5nMpH: 7.5 T: 2°CAssay Description:The DNA-binding competition assay was performed in 25 μL, in black 384-well plates, using either 30 mM HEPES (N-2-Hydroxyethylpiperazine-N'-2-Etha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor SOX-18(Mus musculus (Mouse))
The University of Queensland

LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)
Affinity DataIC50:  2.20E+5nMpH: 7.5 T: 2°CAssay Description:The DNA-binding competition assay was performed in 25 μL, in black 384-well plates, using either 30 mM HEPES (N-2-Hydroxyethylpiperazine-N'-2-Etha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor SOX-18(Mus musculus (Mouse))
The University of Queensland

LigandPNGBDBM223295(Sm8 | US20240002326, Compound Sm8)
Affinity DataIC50:  3.27E+5nMpH: 7.5 T: 2°CAssay Description:The DNA-binding competition assay was performed in 25 μL, in black 384-well plates, using either 30 mM HEPES (N-2-Hydroxyethylpiperazine-N'-2-Etha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor SOX-18(Mus musculus (Mouse))
The University of Queensland

LigandPNGBDBM50259931(6-Tridecylsalicylic acid (Sm2) | 6-tridecyl phenol...)
Affinity DataIC50:  3.41E+5nMpH: 7.5 T: 2°CAssay Description:The DNA-binding competition assay was performed in 25 μL, in black 384-well plates, using either 30 mM HEPES (N-2-Hydroxyethylpiperazine-N'-2-Etha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor SOX-18(Mus musculus (Mouse))
The University of Queensland

LigandPNGBDBM223292(6-Undecylsalicylic acid (Sm1) | US20240002326, Com...)
Affinity DataIC50:  3.48E+5nMpH: 7.5 T: 2°CAssay Description:The DNA-binding competition assay was performed in 25 μL, in black 384-well plates, using either 30 mM HEPES (N-2-Hydroxyethylpiperazine-N'-2-Etha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranscription factor SOX-18(Mus musculus (Mouse))
The University of Queensland

LigandPNGBDBM85507(CAS_4394-00-7 | NSC_4488 | Niflumic acid | Niflumi...)
Affinity DataIC50:  3.75E+5nMpH: 7.5 T: 2°CAssay Description:The DNA-binding competition assay was performed in 25 μL, in black 384-well plates, using either 30 mM HEPES (N-2-Hydroxyethylpiperazine-N'-2-Etha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor SOX-18(Mus musculus (Mouse))
The University of Queensland

LigandPNGBDBM223298(Sm13 | US20240002326, Compound Sm13)
Affinity DataIC50:  4.81E+5nMpH: 7.5 T: 2°CAssay Description:The DNA-binding competition assay was performed in 25 μL, in black 384-well plates, using either 30 mM HEPES (N-2-Hydroxyethylpiperazine-N'-2-Etha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor SOX-18(Mus musculus (Mouse))
The University of Queensland

LigandPNGBDBM223294(Sm5)
Affinity DataIC50:  1.11E+6nMpH: 7.5 T: 2°CAssay Description:The DNA-binding competition assay was performed in 25 μL, in black 384-well plates, using either 30 mM HEPES (N-2-Hydroxyethylpiperazine-N'-2-Etha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranscription factor SOX-18(Mus musculus (Mouse))
The University of Queensland

LigandPNGBDBM223297(Sm12 | US20240002326, Compound Sm12)
Affinity DataIC50:  2.88E+6nMpH: 7.5 T: 2°CAssay Description:The DNA-binding competition assay was performed in 25 μL, in black 384-well plates, using either 30 mM HEPES (N-2-Hydroxyethylpiperazine-N'-2-Etha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor SOX-18(Mus musculus (Mouse))
The University of Queensland

LigandPNGBDBM223296(Sm11 | US20240002326, Compound Sm11)
Affinity DataIC50:  3.80E+6nMpH: 7.5 T: 2°CAssay Description:The DNA-binding competition assay was performed in 25 μL, in black 384-well plates, using either 30 mM HEPES (N-2-Hydroxyethylpiperazine-N'-2-Etha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50030474(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
Affinity DataEC50:  27nMAssay Description:Agonist activity at Gal4-fused PPARgamma (unknown origin) expressed in human U2OS cells co-transfected with pSG5 expression vector preincubated for 4...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50586288(CHEMBL5070753)
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at Gal4-fused PPARgamma (unknown origin) expressed in human U2OS cells co-transfected with pSG5 expression vector preincubated for 4...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed