Affinity DataKi: 5.93E+4nMAssay Description:Binding affinity to Bacillus thermoproteolyticus Thermolysin assessed as inhibition constant by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 21nMAssay Description:Inhibition of wild type human EGFR measured by ELISA analysisMore data for this Ligand-Target Pair
Ligand Info
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA
Affinity DataIC50: 56nMAssay Description:Inhibition of PI3Kdelta (unknown origin) incubated for 90 mins by [gamma-33P]-ATP based scintillation counting methodMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
Ligand Info
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA
Affinity DataIC50: 82nMAssay Description:Inhibition of PI3Kdelta (unknown origin) incubated for 90 mins by [gamma-33P]-ATP based scintillation counting methodMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
Ligand Info
Affinity DataIC50: 100nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 102nMAssay Description:Inhibition of wild type human EGFR measured by ELISA analysisMore data for this Ligand-Target Pair
Ligand Info
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA
Affinity DataIC50: 140nMAssay Description:Inhibition of PI3Kdelta (unknown origin) incubated for 90 mins by [gamma-33P]-ATP based scintillation counting methodMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
Ligand Info
Affinity DataIC50: 300nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))TBA
Affinity DataIC50: 420nMAssay Description:Inhibition of PI3Kgamma (unknown origin) incubated for 90 mins by [gamma-33P]-ATP based scintillation counting methodMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
Ligand Info
Affinity DataIC50: 780nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))TBA
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of PI3Kgamma (unknown origin) incubated for 90 mins by [gamma-33P]-ATP based scintillation counting methodMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
Ligand Info
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of sheep COX1 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 6.86E+3nMAssay Description:Inhibition of sheep COX1 by spectrophotometryMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of PI3Kdelta (unknown origin) incubated for 90 mins by [gamma-33P]-ATP based scintillation counting methodMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
Ligand Info
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))TBA
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) incubated for 90 mins by [gamma-33P]-ATP based scintillation counting methodMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
Ligand Info
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PI3Kalpha in rat Rat1 cells reduction in phosphorylation of AKT at Ser473 residue incubated for 2 hrs by alpha screen assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PI3Kalpha in rat Rat1 cells reduction in phosphorylation of AKT at Ser473 residue incubated for 2 hrs by alpha screen assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PI3Kalpha in rat Rat1 cells reduction in phosphorylation of AKT at Ser473 residue incubated for 2 hrs by alpha screen assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PI3Kalpha in rat Rat1 cells reduction in phosphorylation of AKT at Ser473 residue incubated for 2 hrs by alpha screen assayMore data for this Ligand-Target Pair
Ligand Info
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))TBA
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PI3Kgamma (unknown origin) incubated for 90 mins by [gamma-33P]-ATP based scintillation counting methodMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
Ligand Info
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))TBA
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PI3Kgamma (unknown origin) incubated for 90 mins by [gamma-33P]-ATP based scintillation counting methodMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
Ligand Info
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))TBA
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PI3Kalpha (unknown origin) incubated for 90 mins by [gamma-33P]-ATP based scintillation counting methodMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
Ligand Info
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))TBA
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PI3Kalpha (unknown origin) incubated for 90 mins by [gamma-33P]-ATP based scintillation counting methodMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
Ligand Info
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))TBA
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PI3Kalpha (unknown origin) incubated for 90 mins by [gamma-33P]-ATP based scintillation counting methodMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
Ligand Info
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of sheep COX1 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.51E+4nMAssay Description:Inhibition of sheep COX1 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.52E+4nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.88E+4nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.92E+4nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.97E+4nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.31E+4nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.35E+4nMAssay Description:Inhibition of sheep COX1 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.65E+4nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.67E+4nMAssay Description:Inhibition of sheep COX1 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 3.46E+4nMAssay Description:Inhibition of sheep COX1 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 3.68E+4nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 4.33E+4nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 7.32E+4nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 7.64E+4nMAssay Description:Inhibition of sheep COX1 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 7.69E+4nMAssay Description:Inhibition of Bacillus thermoproteolyticus ThermolysinMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 7.87E+4nMAssay Description:Inhibition of sheep COX1 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of sheep COX1 by spectrophotometryMore data for this Ligand-Target Pair