Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]- spiperone radioligand binding at the dopamine binding site of rat caudateMore data for this Ligand-Target Pair
Affinity DataKi: 0.490nMAssay Description:In vitro binding to human erythrocyte carbonic anhydrase was determined by fluorescence competition assay employing the fluorescent CA inhibitor dans...More data for this Ligand-Target Pair
Affinity DataKi: 0.690nMAssay Description:The equilibrium dissociation constant of the inhibitor-enzyme complex of human Carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:50% inhibitory concentration against human carbonic anhydrase II (HCA II) after pre-incubation for 4 min at 37 degree CMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:The equilibrium dissociation constant of the inhibitor-enzyme complex of human Carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 0.770nMAssay Description:Evaluated for its ability to displace [3H]-clonidine from alpha-2 adrenergic receptor of calf cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 0.820nMAssay Description:50% inhibitory concentration against human carbonic anhydrase II (HCA II) after pre-incubation at 3 degree CMore data for this Ligand-Target Pair
Affinity DataKi: 0.930nMAssay Description:Binding affinity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]prazosin as the radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:The equilibrium dissociation constant of the inhibitor-enzyme complex of human Carbonic anhydrase IIMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Compound was tested for inhibition of human plasma reninMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:In vitro inhibition against purified human erythrocyte carbonic anhydrase II was determined (acetozolamide used as control.)More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Compound was evaluated for the inhibition of dansylamide at human carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Inhibition of human carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Evaluated for its ability to displace [3H]-clonidine from alpha-2 adrenergic receptor of calf cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Binding activity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]-clonidine as the radioligandMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Compound was tested for inhibition of hog kidney reninMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Binding affinity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]clonidine as the radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Binding affinity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]clonidine as the radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:The equilibrium dissociation constant of the inhibitor-enzyme complex of human Carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [3H]- spiperone radioligand binding at the dopamine binding site of rat caudateMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Binding affinity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]prazosin as the radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:The equilibrium dissociation constant of the inhibitor-enzyme complex of human Carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Inhibition of human carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 2.34nMAssay Description:Compound was tested in vitro for binding affinity against human carbonic anhydrase II; (ki*10e-9)More data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Compound was evaluated for the inhibition of dansylamide at human carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Binding activity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]-clonidine as the radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Binding activity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]-clonidine as the radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:In vitro binding to human erythrocyte carbonic anhydrase was determined by fluorescence competition assay employing the fluorescent CA inhibitor dans...More data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Binding affinity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]clonidine as the radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Compound was tested in vitro for binding affinity against human carbonic anhydrase II; (ki*10e-9)More data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Compound was evaluated for the inhibition of dansylamide at human carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 3.60nMAssay Description:In vitro inhibition against purified human erythrocyte carbonic anhydrase II was determined (acetozolamide used as control.)More data for this Ligand-Target Pair
Affinity DataKi: 3.60nMAssay Description:Compound was evaluated for the inhibition of dansylamide at human carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 3.70nMAssay Description:The equilibrium dissociation constant of the inhibitor-enzyme complex of human Carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of [3H]- QNB binding at the muscarinic-cholinergic binding site of rat brain S1More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:In vitro inhibition of Histamine H2 receptor by measuring its ability to block the histamine-stimulated adenylate cyclase of guinea pig hippocampal h...More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of human carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Affinity to alpha-2 adrenergic receptor by the displacement of [3H]-clonidine from calf cerebral cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Affinity to alpha-2 adrenergic receptor by the displacement of [3H]-clonidine from calf cerebral cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Binding activity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]-clonidine as the radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:Binding affinity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]prazosin as the radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 6.20nMAssay Description:50% inhibitory concentration against human carbonic anhydrase II (HCA II) after pre-incubation for 4 min at 37 degree CMore data for this Ligand-Target Pair
Affinity DataKi: 6.30nMAssay Description:In vitro inhibition of Histamine H2 receptor by measuring its ability to block the histamine-stimulated adenylate cyclase of guinea pig hippocampal h...More data for this Ligand-Target Pair
Affinity DataKi: 6.30nMAssay Description:In vitro inhibition of Histamine H2 receptor by measuring its ability to block the histamine-stimulated adenylate cyclase of guinea pig hippocampal h...More data for this Ligand-Target Pair
Affinity DataKi: 6.5nMAssay Description:Compound was tested in vitro for binding affinity against human carbonic anhydrase II; (ki*10e-9)More data for this Ligand-Target Pair
Affinity DataKi: 6.60nMAssay Description:Displacement of [3H]- apomorphine radioligand binding at the dopamine binding site of rat caudateMore data for this Ligand-Target Pair
Affinity DataKi: 6.70nMAssay Description:In vitro inhibition against purified human erythrocyte carbonic anhydrase II was determined (acetozolamide used as control.)More data for this Ligand-Target Pair
Affinity DataKi: 6.80nMAssay Description:The equilibrium dissociation constant of the inhibitor-enzyme complex of human Carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 6.80nMAssay Description:Displacement of [3H]- apomorphine radioligand binding at the dopamine binding site of rat caudateMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Displacement of [3H]- spiperone radioligand binding at the dopamine binding site of rat caudateMore data for this Ligand-Target Pair