Affinity DataKi: 0.600nMAssay Description:Inhibitory activity of the compound towards ThrombinMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Inhibitory activity of the compound towards ThrombinMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Inhibitory concentration of the compound required against thrombin was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Inhibitory activity of the compound against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Binding affinity against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibitory activity of the compound against human thrombinMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research
Parke-Davis Pharmaceutical Research
Affinity DataKi: 33nM ΔG°: -44.4kJ/mole IC50: 58nMpH: 4.7 T: 2°CAssay Description:For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)...More data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Binding affinity against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Binding affinity against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 65nMAssay Description:Inhibitory activity of the compound against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 75nMAssay Description:Binding affinity against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 98nMAssay Description:Binding affinity against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 105nMAssay Description:Binding affinity against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Binding affinity against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 165nMAssay Description:Binding affinity against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Inhibitory activity of the compound against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 495nMAssay Description:Binding affinity against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 4.00E+3nMAssay Description:Inhibitory activity of the compound towards TrypsinMore data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:Inhibitory activity against monkey renin in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:In vitro inhibitory activity against monkey plasma reninMore data for this Ligand-Target Pair
Affinity DataIC50: 0.170nMAssay Description:Inhibitory activity against monkey renin in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 0.180nMAssay Description:Inhibitory activity against monkey renin in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of ET-1 binding to Endothelin A receptor in cultured rabbit renal artery vascular smooth muscle cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:The compound was evaluated for inhibitory activity against monkey plasma renin.More data for this Ligand-Target Pair
Affinity DataIC50: 0.210nMAssay Description:Inhibitory activity against monkey renin in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 0.220nMAssay Description:Inhibitory activity against monkey renin in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 0.230nMAssay Description:Inhibitory activity against monkey reninMore data for this Ligand-Target Pair
Affinity DataIC50: 0.25nMAssay Description:Inhibitory activity against monkey renin in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 0.360nMAssay Description:In vitro inhibitory activity against monkey plasma reninMore data for this Ligand-Target Pair
Affinity DataIC50: 0.420nMAssay Description:In vitro inhibitory activity against monkey plasma reninMore data for this Ligand-Target Pair
Affinity DataIC50: 0.440nMAssay Description:Inhibitory activity against monkey renin in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 0.520nMAssay Description:Inhibitory activity against monkey renin in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:In vitro inhibitory activity against thrombin(FIIa)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory activity of the compound towards TrypsinMore data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:In vitro inhibitory activity against thrombin(FIIa)More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:In vitro inhibitory activity against human trypsinMore data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:In vitro inhibitory activity against human trypsinMore data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of human ThrombinMore data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of human ThrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibitory activity against monkey renin in vitro.More data for this Ligand-Target Pair