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Found 318 with Last Name = 'rico-bautista' and Initial = 'e'
TargetCytochrome P450 2D6(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50592188(CHEMBL5176490)
Affinity DataIC50:  90nMAssay Description:Time dependent inhibition of CYP2D6 (unknown origin) preincubated for 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50592196(CHEMBL5174433)
Affinity DataIC50:  280nMAssay Description:Inhibition of hERG by patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50592188(CHEMBL5176490)
Affinity DataIC50:  400nMAssay Description:Time dependent inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50592194(CHEMBL5195355)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of hERG by patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546560(CHEMBL4778342)
Affinity DataIC50:  3.16E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546560(CHEMBL4778342)
Affinity DataIC50:  3.16E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50592196(CHEMBL5174433)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin) preincubated for 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50592196(CHEMBL5174433)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50592194(CHEMBL5195355)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin) preincubated for 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50592194(CHEMBL5195355)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50592194(CHEMBL5195355)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin) by fluorescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50592194(CHEMBL5195355)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin) by fluorescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546560(CHEMBL4778342)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546560(CHEMBL4778342)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546560(CHEMBL4778342)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546560(CHEMBL4778342)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50592196(CHEMBL5174433)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) preincubated for 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546560(CHEMBL4778342)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546560(CHEMBL4778342)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50592194(CHEMBL5195355)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) preincubated for 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50592194(CHEMBL5195355)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50592196(CHEMBL5174433)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546560(CHEMBL4778342)
Affinity DataIC50:  2.00E+6nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546560(CHEMBL4778342)
Affinity DataIC50:  2.00E+6nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546560(CHEMBL4778342)
Affinity DataEC50:  63nMAssay Description:Agonist activity at human N-terminal HA-tagged SST2 expressed in cell assessed as induction of receptor internalization by colorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546560(CHEMBL4778342)
Affinity DataEC50:  63nMAssay Description:Agonist activity at human N-terminal HA-tagged SST2 expressed in cell assessed as induction of receptor internalization by colorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546560(CHEMBL4778342)
Affinity DataEC50:  0.501nMAssay Description:Agonist activity at human SST4More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546560(CHEMBL4778342)
Affinity DataEC50:  0.501nMAssay Description:Agonist activity at human SST4More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546560(CHEMBL4778342)
Affinity DataEC50: <1.00E+3nMAssay Description:Agonist activity at human SST5More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546560(CHEMBL4778342)
Affinity DataEC50: <1.00E+3nMAssay Description:Agonist activity at human SST5More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 1(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546560(CHEMBL4778342)
Affinity DataEC50:  316nMAssay Description:Agonist activity at human SST1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 1(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546560(CHEMBL4778342)
Affinity DataEC50:  316nMAssay Description:Agonist activity at human SST1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546560(CHEMBL4778342)
Affinity DataEC50:  7.90nMAssay Description:Agonist activity at human SST3More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546560(CHEMBL4778342)
Affinity DataEC50:  7.90nMAssay Description:Agonist activity at human SST3More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546561(CHEMBL4750168)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at human SST2 expressed in CHOK1 cells assessed as inhibition of NKH477-stimulated intracellular cAMP levelsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546561(CHEMBL4750168)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at human SST2 expressed in CHOK1 cells assessed as inhibition of NKH477-stimulated intracellular cAMP levelsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546562(CHEMBL4741139)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human SST2 expressed in CHOK1 cells assessed as inhibition of NKH477-stimulated intracellular cAMP levelsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546562(CHEMBL4741139)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human SST2 expressed in CHOK1 cells assessed as inhibition of NKH477-stimulated intracellular cAMP levelsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546563(CHEMBL4749667)
Affinity DataEC50:  316nMAssay Description:Agonist activity at human SST2 expressed in CHOK1 cells assessed as inhibition of NKH477-stimulated intracellular cAMP levelsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546563(CHEMBL4749667)
Affinity DataEC50:  316nMAssay Description:Agonist activity at human SST2 expressed in CHOK1 cells assessed as inhibition of NKH477-stimulated intracellular cAMP levelsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546564(CHEMBL4782501)
Affinity DataEC50:  32nMAssay Description:Agonist activity at human SST2 expressed in CHOK1 cells assessed as inhibition of NKH477-stimulated intracellular cAMP levelsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546564(CHEMBL4782501)
Affinity DataEC50:  32nMAssay Description:Agonist activity at human SST2 expressed in CHOK1 cells assessed as inhibition of NKH477-stimulated intracellular cAMP levelsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546565(CHEMBL4761276)
Affinity DataEC50:  251nMAssay Description:Agonist activity at human SST2 expressed in CHOK1 cells assessed as inhibition of NKH477-stimulated intracellular cAMP levelsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546565(CHEMBL4761276)
Affinity DataEC50:  251nMAssay Description:Agonist activity at human SST2 expressed in CHOK1 cells assessed as inhibition of NKH477-stimulated intracellular cAMP levelsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546566(CHEMBL4776516)
Affinity DataEC50:  200nMAssay Description:Agonist activity at human SST2 expressed in CHOK1 cells assessed as inhibition of NKH477-stimulated intracellular cAMP levelsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546566(CHEMBL4776516)
Affinity DataEC50:  200nMAssay Description:Agonist activity at human SST2 expressed in CHOK1 cells assessed as inhibition of NKH477-stimulated intracellular cAMP levelsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546567(CHEMBL4799254)
Affinity DataEC50:  40nMAssay Description:Agonist activity at human SST2 expressed in CHOK1 cells assessed as inhibition of NKH477-stimulated intracellular cAMP levelsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546567(CHEMBL4799254)
Affinity DataEC50:  40nMAssay Description:Agonist activity at human SST2 expressed in CHOK1 cells assessed as inhibition of NKH477-stimulated intracellular cAMP levelsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546568(CHEMBL4752814)
Affinity DataEC50:  63nMAssay Description:Agonist activity at human SST2 expressed in CHOK1 cells assessed as inhibition of NKH477-stimulated intracellular cAMP levelsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546568(CHEMBL4752814)
Affinity DataEC50:  63nMAssay Description:Agonist activity at human SST2 expressed in CHOK1 cells assessed as inhibition of NKH477-stimulated intracellular cAMP levelsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
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