Compile Data Set for Download or QSAR
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Found 102 with Last Name = 'rihs' and Initial = 'g'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040929(4,5-dianilinophthalimide | 5,6-bis(phenylamino)-1H...)
Affinity DataKi:  160nMAssay Description:Competitive inhibition of ATP binding to EGF-RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50047259(4-(1-(1H-imidazol-1-yl)vinyl)benzonitrile | 4-(1-I...)
Affinity DataIC50:  0.700nMAssay Description:In vitro inhibition of human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50047261(5-(1H-imidazol-1-yl)-7,8-dihydronaphthalene-2-carb...)
Affinity DataIC50:  2.90nMAssay Description:In vitro inhibition of human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM9920((S)Fadrozole | 4-[(5S)-5,6,7,8-tetrahydroimidazo[1...)
Affinity DataIC50:  3.20nMAssay Description:In vitro inhibition of human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50047260(4,4'-((1H-imidazol-1-yl)methylene)dibenzonitrile |...)
Affinity DataIC50:  3.5nMAssay Description:In vitro inhibition of human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50047264(4-((4-bromophenylimino)(1H-imidazol-1-yl)methyl)be...)
Affinity DataIC50:  7.70nMAssay Description:In vitro inhibition of human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50047263(4-[5-(4-cyanophenyl)-5,6,7,8-tetrahydroimidazo[1,5...)
Affinity DataIC50:  233nMAssay Description:In vitro inhibition of human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040929(4,5-dianilinophthalimide | 5,6-bis(phenylamino)-1H...)
Affinity DataIC50:  300nMAssay Description:Inhibitory activity against recombinant tyrosine kinase EGF-R (EGF-R ICD)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50409037(CHEMBL2111944)
Affinity DataIC50:  430nMAssay Description:Inhibition of Quisqualate-Induced PI Hydrolysis measured in CHO Metabotropic glutamate receptor 1 Expressing CellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50047262((R)-4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-y...)
Affinity DataIC50:  680nMAssay Description:In vitro inhibition of human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040930(5,6-Bis-(4-fluoro-phenylamino)-isoindole-1,3-dione...)
Affinity DataIC50:  700nMAssay Description:Inhibitory activity against recombinant tyrosine kinase EGF-R (EGF-R ICD)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50409038(CHEMBL2111943)
Affinity DataIC50:  930nMAssay Description:Inhibition of Quisqualate-Induced PI Hydrolysis Measured in CHO Metabotropic glutamate receptor 1 Expressing CellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040917(5-(Methyl-phenyl-amino)-6-phenylamino-isoindole-1,...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory activity against c-src tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM19459(5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory activity against recombinant tyrosine kinase EGF-R (EGF-R ICD)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50094187((+)1aR,7aR -2-[(2-Hydroxyimino-1a,2-dihydro-1H-7-o...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of Quisqualate-Induced PI Hydrolysis measured in CHO Metabotropic glutamate receptor 1 Expressing CellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50094188((+)1aR,7aR -2-[(2-Hydroxyimino-1a,2-dihydro-1H-7-o...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of Quisqualate-Induced PI Hydrolysis measured in CHO Metabotropic glutamate receptor 1 Expressing CellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50409036(CHEMBL2111945)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of Quisqualate-Induced PI Hydrolysis measured in CHO Metabotropic glutamate receptor 1 Expressing CellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)
Affinity DataIC50:  1.90E+3nMAssay Description:In vitro inhibition of human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040930(5,6-Bis-(4-fluoro-phenylamino)-isoindole-1,3-dione...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of EGF-dependent autophosphorylation of EGF-R in human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040916(5,6-Bis-(4-hydroxy-phenylamino)-isoindole-1,3-dion...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibitory activity against recombinant tyrosine kinase EGF-R (EGF-R ICD)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040920(5,6-Bis-p-tolylamino-isoindole-1,3-dione | CHEMBL7...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibitory activity against recombinant tyrosine kinase EGF-R (EGF-R ICD)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM86213(CAS_5126051 | CHEMBL327783 | CPCCOEt | NSC_5126051)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of Quisqualate-Induced PI Hydrolysis measured in CHO Metabotropic glutamate receptor 1 Expressing CellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040929(4,5-dianilinophthalimide | 5,6-bis(phenylamino)-1H...)
Affinity DataIC50: >4.50E+3nMAssay Description:Inhibition of EGF-dependent autophosphorylation of EGF-R in human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040920(5,6-Bis-p-tolylamino-isoindole-1,3-dione | CHEMBL7...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of EGF-dependent autophosphorylation of EGF-R in human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040916(5,6-Bis-(4-hydroxy-phenylamino)-isoindole-1,3-dion...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibitory activity against c-src tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040917(5-(Methyl-phenyl-amino)-6-phenylamino-isoindole-1,...)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibitory activity against recombinant tyrosine kinase EGF-R (EGF-R ICD)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-dependent protein kinase(Oryctolagus cuniculus (Rabbit))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM2672(3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity was determined against protein kinase A (PKA) of rabbitMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040917(5-(Methyl-phenyl-amino)-6-phenylamino-isoindole-1,...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of PDGF-dependent autophosphorylation of PDGF-R in mouse BALB/c3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040916(5,6-Bis-(4-hydroxy-phenylamino)-isoindole-1,3-dion...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibitory activity against v-abl tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040929(4,5-dianilinophthalimide | 5,6-bis(phenylamino)-1H...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibitory activity against c-src tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040914(5-(4-Methoxy-phenylamino)-6-phenylamino-isoindole-...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of EGF-dependent autophosphorylation of EGF-R in human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040914(5-(4-Methoxy-phenylamino)-6-phenylamino-isoindole-...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of EGF-dependent autophosphorylation of EGF-R in human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM2583(3,4-Bis(3-indolyl)-1H-pyrrole-2,5-dione | 3,4-bis(...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibitory activity against v-abl tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040923(2-Methyl-5,6-bis-phenylamino-isoindole-1,3-dione |...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of EGF-dependent autophosphorylation of EGF-R in human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040919(5,6-Bis-(biphenyl-4-ylamino)-isoindole-1,3-dione |...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory activity against recombinant tyrosine kinase EGF-R (EGF-R ICD)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040922(2-Phenyl-5,6-bis-phenylamino-isoindole-1,3-dione |...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of EGF-dependent autophosphorylation of EGF-R in human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040922(2-Phenyl-5,6-bis-phenylamino-isoindole-1,3-dione |...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of EGF-dependent autophosphorylation of EGF-R in human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040925(5,6-Bis-(4-methoxy-phenylamino)-isoindole-1,3-dion...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory activity against recombinant tyrosine kinase EGF-R (EGF-R ICD)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040927(CHEMBL268441 | N-(1,3-Dioxo-6-phenylamino-2,3-dihy...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory activity against recombinant tyrosine kinase EGF-R (EGF-R ICD)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040913(1,4-Diphenyl-1,2,3,4-tetrahydro-pyrrolo[3,4-g]quin...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory activity against c-src tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040912(5,6-Bis-cyclohexylamino-isoindole-1,3-dione | CHEM...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory activity against c-src tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040913(1,4-Diphenyl-1,2,3,4-tetrahydro-pyrrolo[3,4-g]quin...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory activity against v-abl tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040917(5-(Methyl-phenyl-amino)-6-phenylamino-isoindole-1,...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory activity against v-abl tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040915(5,6-Bis-(4-iodo-phenylamino)-isoindole-1,3-dione |...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory activity against recombinant tyrosine kinase EGF-R (EGF-R ICD)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040918(5,6-Bis-(methyl-phenyl-amino)-isoindole-1,3-dione ...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory activity against v-abl tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040923(2-Methyl-5,6-bis-phenylamino-isoindole-1,3-dione |...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory activity against recombinant tyrosine kinase EGF-R (EGF-R ICD)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM2583(3,4-Bis(3-indolyl)-1H-pyrrole-2,5-dione | 3,4-bis(...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory activity against recombinant tyrosine kinase EGF-R (EGF-R ICD)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040930(5,6-Bis-(4-fluoro-phenylamino)-isoindole-1,3-dione...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibitory activity against c-src tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040927(CHEMBL268441 | N-(1,3-Dioxo-6-phenylamino-2,3-dihy...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of EGF-dependent autophosphorylation of EGF-R in human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040929(4,5-dianilinophthalimide | 5,6-bis(phenylamino)-1H...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory activity against v-abl tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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