TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human CYP11B2 expressed in V79 cells incubated for 1 hr before 11-deoxycorticosterone substrate addition by HTRF-based assayMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human CYP11B2 expressed in V79 cells incubated for 1 hr before 11-deoxycorticosterone substrate addition by HTRF-based assayMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human CYP11B2 expressed in V79 cells incubated for 1 hr before 11-deoxycorticosterone substrate addition by HTRF-based assayMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human CYP11B2 expressed in V79 cells incubated for 1 hr before 11-deoxycorticosterone substrate addition by HTRF-based assayMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human CYP11B2 expressed in V79 cells incubated for 1 hr before 11-deoxycorticosterone substrate addition by HTRF-based assayMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human CYP11B2 expressed in V79 cells incubated for 1 hr before 11-deoxycorticosterone substrate addition by HTRF-based assayMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human CYP11B2 expressed in V79 cells incubated for 1 hr before 11-deoxycorticosterone substrate addition by HTRF-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Enzyme activities were measured in the presence of the test inhibitor in spectrophotometric assay.More data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human CYP11B2 expressed in V79 cells incubated for 1 hr before 11-deoxycorticosterone substrate addition by HTRF-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Enzyme activities were measured in the presence of the test inhibitor in spectrophotometric assay.More data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human CYP11B2 expressed in V79 cells incubated for 1 hr before 11-deoxycorticosterone substrate addition by HTRF-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Enzyme activities were measured in the presence of the test inhibitor in spectrophotometric assay.More data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human CYP11B2 expressed in V79 cells incubated for 1 hr before 11-deoxycorticosterone substrate addition by HTRF-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Enzyme activities were measured in the presence of the test inhibitor in spectrophotometric assay.More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Enzyme activities were measured in the presence of the test inhibitor in spectrophotometric assay.More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Enzyme activities were measured in the presence of the test inhibitor in spectrophotometric assay.More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Enzyme activities were measured in the presence of the test inhibitor in spectrophotometric assay.More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Enzyme activities were measured in the presence of the test inhibitor in spectrophotometric assay.More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Enzyme activities were measured in the presence of the test inhibitor in spectrophotometric assay.More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Enzyme activities were measured in the presence of the test inhibitor in spectrophotometric assay.More data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human CYP11B2 expressed in V79 cells incubated for 1 hr before 11-deoxycorticosterone substrate addition by HTRF-based assayMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human CYP11B2 expressed in V79 cells incubated for 1 hr before 11-deoxycorticosterone substrate addition by HTRF-based assayMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human CYP11B2 expressed in V79 cells incubated for 1 hr before 11-deoxycorticosterone substrate addition by HTRF-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Enzyme activities were measured in the presence of the test inhibitor in spectrophotometric assay.More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Enzyme activities were measured in the presence of the test inhibitor in spectrophotometric assay.More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Enzyme activities were measured in the presence of the test inhibitor in spectrophotometric assay.More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Enzyme activities were measured in the presence of the test inhibitor in spectrophotometric assay.More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Enzyme activities were measured in the presence of the test inhibitor in spectrophotometric assay.More data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human CYP11B2 expressed in V79 cells incubated for 1 hr before 11-deoxycorticosterone substrate addition by HTRF-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Enzyme activities were measured in the presence of the test inhibitor in spectrophotometric assay.More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Enzyme activities were measured in the presence of the test inhibitor in spectrophotometric assay.More data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human CYP11B2 expressed in V79 cells incubated for 1 hr before 11-deoxycorticosterone substrate addition by HTRF-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Enzyme activities were measured in the presence of the test inhibitor in spectrophotometric assay.More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Enzyme activities were measured in the presence of the test inhibitor in spectrophotometric assay.More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Enzyme activities were measured in the presence of the test inhibitor in spectrophotometric assay.More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Enzyme activities were measured in the presence of the test inhibitor in spectrophotometric assay.More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Enzyme activities were measured in the presence of the test inhibitor in spectrophotometric assay.More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Enzyme activities were measured in the presence of the test inhibitor in spectrophotometric assay.More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Enzyme activities were measured in the presence of the test inhibitor in spectrophotometric assay.More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Enzyme activities were measured in the presence of the test inhibitor in spectrophotometric assay.More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Enzyme activities were measured in the presence of the test inhibitor in spectrophotometric assay.More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Enzyme activities were measured in the presence of the test inhibitor in spectrophotometric assay.More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Enzyme activities were measured in the presence of the test inhibitor in spectrophotometric assay.More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Enzyme activities were measured in the presence of the test inhibitor in spectrophotometric assay.More data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 8.10nMAssay Description:Inhibition of human CYP11B2 expressed in V79 cells incubated for 1 hr before 11-deoxycorticosterone substrate addition by HTRF-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Enzyme activities were measured in the presence of the test inhibitor in spectrophotometric assay.More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Enzyme activities were measured in the presence of the test inhibitor in spectrophotometric assay.More data for this Ligand-Target Pair
Affinity DataIC50: 9.5nMAssay Description:Enzyme activities were measured in the presence of the test inhibitor in spectrophotometric assay.More data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human CYP11B2 expressed in V79 cells incubated for 1 hr before 11-deoxycorticosterone substrate addition by HTRF-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Enzyme activities were measured in the presence of the test inhibitor in spectrophotometric assay.More data for this Ligand-Target Pair