Affinity DataIC50: 0.5nMAssay Description:Inhibition of eIF4A1-mediated protein synthesis in human BJAB cells assessed as inhibition of [35S]Met incorporation after 72 hr by scintillation cou...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF methodMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of eIF4A1-mediated protein synthesis in human BJAB cells assessed as inhibition of [35S]Met incorporation after 1 hr by scintillation coun...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Brain Mind Institute
Curated by ChEMBL
Brain Mind Institute
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of human MIF tautomerase activityMore data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Brain Mind Institute
Curated by ChEMBL
Brain Mind Institute
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of human MIF tautomerase activity in presence of Triton X-100 as detergentMore data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
Affinity DataIC50: 68nMAssay Description:Displacement of [3H]19 from human mGlu2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 71nMAssay Description:Inhibition of BRD2-BD2 (unknown origin) incubated for 6 hrs by HTRF methodMore data for this Ligand-Target Pair
Affinity DataIC50: 72nMAssay Description:Inhibition of BRD3-BD2 (unknown origin) assessed as dissociation constant by TR-FRET methodMore data for this Ligand-Target Pair
Affinity DataIC50: 72nMAssay Description:Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF methodMore data for this Ligand-Target Pair
Affinity DataIC50: 77nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Brain Mind Institute
Curated by ChEMBL
Brain Mind Institute
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of human MIF tautomerase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 85nMAssay Description:Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF methodMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
Affinity DataIC50: 98nMAssay Description:Inhibition of BRD3-BD2 (unknown origin) assessed as dissociation constant by TR-FRET methodMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF methodMore data for this Ligand-Target Pair
Affinity DataIC50: 108nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of BRD2-BD2 (unknown origin) incubated for 6 hrs by HTRF methodMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of BRD4-BD2 (unknown origin) incubated for 6 hrs by HTRF methodMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF methodMore data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Brain Mind Institute
Curated by ChEMBL
Brain Mind Institute
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of human MIF tautomerase activity in presence of Triton X-100 as detergentMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF methodMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF methodMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF methodMore data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF methodMore data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF methodMore data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF methodMore data for this Ligand-Target Pair
Affinity DataIC50: 251nMAssay Description:Inhibition of TEV cleavage site-fused-GST tagged BRD4(BD1) (unknown origin) using SGRGK(Ac)CGK(Ac)-GLGK(Ac)GGAK(Ac)RHRKVG-peptide after 3 hrs by HTRF...More data for this Ligand-Target Pair
Affinity DataIC50: 251nMAssay Description:Inhibition of TEV cleavage site-fused-GST tagged BRD4(BD1) (unknown origin) using SGRGK(Ac)CGK(Ac)-GLGK(Ac)GGAK(Ac)RHRKVG-peptide after 3 hrs by HTRF...More data for this Ligand-Target Pair
Affinity DataIC50: 262nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF methodMore data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Brain Mind Institute
Curated by ChEMBL
Brain Mind Institute
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of human MIF tautomerase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 316nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
Affinity DataIC50: 316nMAssay Description:Inhibition of TEV cleavage site-fused-GST tagged BRD4(BD1) (unknown origin) using SGRGK(Ac)CGK(Ac)-GLGK(Ac)GGAK(Ac)RHRKVG-peptide after 3 hrs by HTRF...More data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF methodMore data for this Ligand-Target Pair
Affinity DataIC50: 325nMAssay Description:Binding affinity to human partial length BRD3-BD2 (G306 to P416) expressed in bacterial system assessed as dissociation constant by BROMOscan methodMore data for this Ligand-Target Pair
Affinity DataIC50: 364nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF methodMore data for this Ligand-Target Pair
Affinity DataIC50: 390nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
Affinity DataIC50: 398nMAssay Description:Inhibition of TEV cleavage site-fused-GST tagged BRD4(BD1) (unknown origin) using SGRGK(Ac)CGK(Ac)-GLGK(Ac)GGAK(Ac)RHRKVG-peptide after 3 hrs by HTRF...More data for this Ligand-Target Pair
Affinity DataIC50: 398nMAssay Description:Inhibition of TEV cleavage site-fused-GST tagged BRD4(BD1) (unknown origin) using SGRGK(Ac)CGK(Ac)-GLGK(Ac)GGAK(Ac)RHRKVG-peptide after 3 hrs by HTRF...More data for this Ligand-Target Pair
Affinity DataIC50: 410nMAssay Description:Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF methodMore data for this Ligand-Target Pair
Affinity DataIC50: 410nMAssay Description:Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF methodMore data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Brain Mind Institute
Curated by ChEMBL
Brain Mind Institute
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of human MIF tautomerase activity in presence of Triton X-100 as detergentMore data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF methodMore data for this Ligand-Target Pair
Affinity DataIC50: 440nMAssay Description:Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF methodMore data for this Ligand-Target Pair
Affinity DataIC50: 470nMAssay Description:Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF methodMore data for this Ligand-Target Pair
Affinity DataIC50: 490nMAssay Description:Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF methodMore data for this Ligand-Target Pair
Affinity DataIC50: 501nMAssay Description:Inhibition of TEV cleavage site-fused-GST tagged BRD4(BD1) (unknown origin) using SGRGK(Ac)CGK(Ac)-GLGK(Ac)GGAK(Ac)RHRKVG-peptide after 3 hrs by HTRF...More data for this Ligand-Target Pair