Affinity DataKi: 45nMAssay Description:Binding affinity against Beta-2 adrenergic receptor in guinea pig lung membranesMore data for this Ligand-Target Pair
Affinity DataKi: 49nMAssay Description:Binding affinity against Beta-2 adrenergic receptor in guinea pig lung membranesMore data for this Ligand-Target Pair
Affinity DataKi: 58nMAssay Description:Binding affinity against beta-2 adrenergic receptor in guinea pig lung membranesMore data for this Ligand-Target Pair
Affinity DataKi: 76nMAssay Description:Binding affinity against Beta-1 adrenergic receptor in guinea pig left ventricleMore data for this Ligand-Target Pair
Affinity DataKi: 87nMAssay Description:Binding affinity against Beta-1 adrenergic receptor in guinea pig left ventricleMore data for this Ligand-Target Pair
Affinity DataKi: 98nMAssay Description:Binding affinity against beta-1 adrenergic receptor in guinea pig left ventricleMore data for this Ligand-Target Pair
Affinity DataKi: 372nMAssay Description:Binding affinity against Beta-2 adrenergic receptor in guinea pig lung membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1.15E+3nMAssay Description:Binding affinity against Beta-1 adrenergic receptor in guinea pig left ventricleMore data for this Ligand-Target Pair
Affinity DataIC50: 282nMAssay Description:Inhibitory activity against U-46,619-induced responses in human platelet aggregation (Thromboxane A2 alpha receptor)More data for this Ligand-Target Pair
Affinity DataIC50: 2.46E+3nMAssay Description:Inhibitory activity against U-46,619-induced responses in human platelet aggregation (Thromboxane A2 alpha receptor)More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Tested for its ability to antagonize epinephrine induced primary wave aggregation in human platelets at alpha-2A-adrenergic receptor sites.More data for this Ligand-Target Pair
Affinity DataIC50: 3.09E+3nMAssay Description:Inhibitory activity against U-46,619-induced responses in human platelet aggregation (Thromboxane A2 alpha receptor)More data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+3nMAssay Description:Tested for its ability to antagonize epinephrine induced primary wave aggregation in human platelets at alpha-2A-adrenergic receptor sites.More data for this Ligand-Target Pair
Affinity DataIC50: 9.10E+3nMAssay Description:Tested for its ability to antagonize epinephrine induced primary wave aggregation in human platelets at alpha-2A-adrenergic receptor sites.More data for this Ligand-Target Pair
Affinity DataIC50: 1.23E+4nMAssay Description:Tested for its ability to antagonize epinephrine induced primary wave aggregation in human platelets at alpha-2A-adrenergic receptor sites.More data for this Ligand-Target Pair
Affinity DataIC50: 3.98E+4nMAssay Description:Inhibitory activity against U-46,619-induced responses in human platelet aggregation (Thromboxane A2 alpha receptor)More data for this Ligand-Target Pair
Affinity DataIC50: 6.19E+4nMAssay Description:Tested for its ability to antagonize epinephrine induced primary wave aggregation in human platelets at alpha-2A-adrenergic receptor sites.More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibitory activity against U-46,619-induced responses in human platelet aggregation (Thromboxane A2 alpha receptor)More data for this Ligand-Target Pair
Affinity DataIC50: 1.58E+5nMAssay Description:Inhibitory activity against U-46,619-induced responses in human platelet aggregation (Thromboxane A2 alpha receptor)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7(Homo sapiens (Human))
Ohio State University
Curated by ChEMBL
Ohio State University
Curated by ChEMBL
Affinity DataIC50: 1.62E+5nMAssay Description:Inhibition of AA+phentolamine by the compound in response of SECMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+5nMAssay Description:Tested for its ability to antagonize epinephrine induced primary wave aggregation in human platelets at alpha-2A-adrenergic receptor sites.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7(Homo sapiens (Human))
Ohio State University
Curated by ChEMBL
Ohio State University
Curated by ChEMBL
Affinity DataIC50: 3.47E+5nMAssay Description:Inhibition of ADP by the compound in response of SECMore data for this Ligand-Target Pair
Affinity DataIC50: 3.80E+5nMAssay Description:Tested for its ability to antagonize epinephrine induced primary wave aggregation in human platelets at alpha-2A-adrenergic receptor sites.More data for this Ligand-Target Pair
Affinity DataIC50: 5.80E+5nMAssay Description:Tested for its ability to antagonize epinephrine induced primary wave aggregation in human platelets at alpha-2A-adrenergic receptor sites.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7(Homo sapiens (Human))
Ohio State University
Curated by ChEMBL
Ohio State University
Curated by ChEMBL
Affinity DataIC50: 6.61E+5nMAssay Description:Inhibition of Arachidonic acid by the compound in response of SECMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7(Homo sapiens (Human))
Ohio State University
Curated by ChEMBL
Ohio State University
Curated by ChEMBL
Affinity DataIC50: 8.13E+5nMAssay Description:Inhibition of U-46,619 + phentolamine by the compound in response of SECMore data for this Ligand-Target Pair
Affinity DataIC50: 8.32E+5nMAssay Description:Inhibitory activity against U-46,619-induced responses in human platelet aggregation (Thromboxane A2 alpha receptor)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7(Homo sapiens (Human))
Ohio State University
Curated by ChEMBL
Ohio State University
Curated by ChEMBL
Affinity DataIC50: 1.55E+6nMAssay Description:Inhibition of U-46,619 by the compound in response of SECMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7(Homo sapiens (Human))
Ohio State University
Curated by ChEMBL
Ohio State University
Curated by ChEMBL
Affinity DataIC50: 2.29E+12nMAssay Description:Stimulatory activity against serotonin secretion (SEC).More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7(Homo sapiens (Human))
Ohio State University
Curated by ChEMBL
Ohio State University
Curated by ChEMBL
Affinity DataIC50: 3.63E+13nMAssay Description:Stimulatory activity against serotonin secretion (SEC).More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7(Homo sapiens (Human))
Ohio State University
Curated by ChEMBL
Ohio State University
Curated by ChEMBL
Affinity DataIC50: 5.50E+13nMAssay Description:Stimulatory activity against serotonin secretion (SEC).More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7(Homo sapiens (Human))
Ohio State University
Curated by ChEMBL
Ohio State University
Curated by ChEMBL
Affinity DataIC50: 6.46E+13nMAssay Description:Stimulatory activity against serotonin secretion (SEC).More data for this Ligand-Target Pair
Affinity DataEC50: 3.55E+3nMAssay Description:Inhibitory activity against Beta-2 adrenergic receptor in guinea pig tracheaMore data for this Ligand-Target Pair
Affinity DataEC50: 174nMAssay Description:Inhibitory activity against Beta-1 adrenergic receptor in guinea pig atria after treatment with the compoundMore data for this Ligand-Target Pair
Affinity DataEC50: >3.16E+4nMAssay Description:Inhibitory activity against Beta-1 adrenergic receptor in guinea pig atria after treatment with the compoundMore data for this Ligand-Target Pair
Affinity DataEC50: 2.24E+3nMAssay Description:Inhibitory activity against Beta-2 adrenergic receptor in guinea pig trachea after treatment with the compoundMore data for this Ligand-Target Pair
Affinity DataEC50: 6.03E+3nMAssay Description:Inhibitory activity against Beta-1 adrenergic receptor in guinea pig atriaMore data for this Ligand-Target Pair
Affinity DataEC50: 240nMAssay Description:Inhibitory activity against Beta-2 adrenergic receptor in guinea pig trachea after treatment with the compoundMore data for this Ligand-Target Pair
Affinity DataEC50: 26nMAssay Description:Inhibitory activity against Beta-2 adrenergic receptor in guinea pig trachea after treatment with the compoundMore data for this Ligand-Target Pair
Affinity DataEC50: 1.18E+3nMAssay Description:Inhibitory activity against Beta-2 adrenergic receptor in guinea pig trachea after treatment with the compoundMore data for this Ligand-Target Pair
Affinity DataEC50: 501nMAssay Description:Inhibitory activity against Beta-1 adrenergic receptor in guinea pig atria after treatment with the compoundMore data for this Ligand-Target Pair
Affinity DataEC50: 295nMAssay Description:Inhibitory activity against Beta-2 adrenergic receptor in guinea pig tracheaMore data for this Ligand-Target Pair
Affinity DataEC50: 2.82E+3nMAssay Description:Inhibitory activity against Beta-1 adrenergic receptor in guinea pig atria after treatment with the compoundMore data for this Ligand-Target Pair
Affinity DataEC50: 2.95E+3nMAssay Description:Inhibitory activity against Beta-1 adrenergic receptor in guinea pig atria after treatment with the compoundMore data for this Ligand-Target Pair
Affinity DataEC50: 240nMAssay Description:Inhibitory activity against Beta-1 adrenergic receptor in guinea pig atriaMore data for this Ligand-Target Pair
Affinity DataEC50: 129nMAssay Description:Inhibitory activity against Beta-2 adrenergic receptor in guinea pig trachea after treatment with the compoundMore data for this Ligand-Target Pair