TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Washington University
Curated by ChEMBL
Washington University
Curated by ChEMBL
Affinity DataIC50: 0.280nMAssay Description:Agonist activity at PPARalpha-LBD expressed in HEK293 cells co-expressing GAL4-DBD after 16 to 19 hrs by beta lactamase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Washington University
Curated by ChEMBL
Washington University
Curated by ChEMBL
Affinity DataIC50: 0.460nMAssay Description:Agonist activity at PPARalpha-LBD expressed in HEK293 cells co-expressing GAL4-DBD after 16 to 19 hrs by beta lactamase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Washington University
Curated by ChEMBL
Washington University
Curated by ChEMBL
Affinity DataIC50: 0.590nMAssay Description:Agonist activity at PPARalpha-LBD expressed in HEK293 cells co-expressing GAL4-DBD after 16 to 19 hrs by beta lactamase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Washington University
Curated by ChEMBL
Washington University
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Agonist activity at PPARalpha-LBD expressed in HEK293 cells co-expressing GAL4-DBD after 16 to 19 hrs by beta lactamase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of human iNOSMore data for this Ligand-Target Pair
Affinity DataIC50: 57.6nMAssay Description:Inhibition of human recombinant iNOS using 1 mM NADH and 2 uM L-arginine after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human nNOSMore data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Washington University
Curated by ChEMBL
Washington University
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of human eNOSMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of human recombinant iNOS using 1 mM NADH and 2 uM L-arginine after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 193nMAssay Description:Inhibition of human recombinant iNOS using 1 mM NADH and 2 uM L-arginine after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of human recombinant iNOS using 1 mM NADH and 2 uM L-arginine after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 282nMAssay Description:Inhibition of human recombinant iNOS using 1 mM NADH and 2 uM L-arginine after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 490nMAssay Description:Inhibition of human recombinant nNOS using 1 mM NADH and 2 uM L-arginine after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 514nMAssay Description:Inhibition of human recombinant nNOS using 1 mM NADH and 2 uM L-arginine after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 685nMAssay Description:Inhibition of human recombinant iNOS using 1 mM NADH and 2 uM L-arginine after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 731nMAssay Description:Inhibition of human recombinant iNOS using 1 mM NADH and 2 uM L-arginine after 30 minsMore data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Washington University
Curated by ChEMBL
Washington University
Curated by ChEMBL
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of human recombinant eNOS using 1 mM NADH and 2 uM L-arginine after 30 minsMore data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Washington University
Curated by ChEMBL
Washington University
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human recombinant eNOS using 1 mM NADH and 2 uM L-arginine after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.78E+3nMAssay Description:Inhibition of human recombinant iNOS using 1 mM NADH and 2 uM L-arginine after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human recombinant iNOS using 1 mM NADH and 2 uM L-arginine after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human recombinant iNOS using 1 mM NADH and 2 uM L-arginine after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human recombinant iNOS using 1 mM NADH and 2 uM L-arginine after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human recombinant iNOS using 1 mM NADH and 2 uM L-arginine after 30 minsMore data for this Ligand-Target Pair