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Found 1060 with Last Name = 'russo' and Initial = 'r'
TargetProcathepsin L(Homo sapiens (Human))
Gnf

LigandPNGBDBM19564((2S)-N-{2-[(4-methoxyphenyl)amino]ethyl}-2-[(3-met...)
Affinity DataKi:  1.10nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Gnf

LigandPNGBDBM19566((2S)-N-{2-[(4-methoxyphenyl)amino]ethyl}-2-[(3-met...)
Affinity DataKi:  1.20nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Gnf

LigandPNGBDBM19553((2S)-3-(4-chlorophenyl)-N-{2-[(4-methoxyphenyl)ami...)
Affinity DataKi:  1.40nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Gnf

LigandPNGBDBM19554((2S)-3-(3-chlorophenyl)-N-{2-[(4-methoxyphenyl)ami...)
Affinity DataKi:  1.5nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19577((2S)-3-cyclohexyl-2-({4-[(4,6-dimethylpyrimidin-2-...)
Affinity DataKi:  2nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Gnf

LigandPNGBDBM19557((2S)-N-{2-[(4-methoxyphenyl)amino]ethyl}-2-[(3-met...)
Affinity DataKi:  2.80nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19570((2S)-3-cyclohexyl-N-{2-[(4-methoxyphenyl)amino]eth...)
Affinity DataKi:  2.90nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19582((2S)-3-cyclohexyl-N-{2-[(4-methoxyphenyl)amino]eth...)
Affinity DataKi:  3.30nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Gnf

LigandPNGBDBM19556((2S)-N-{2-[(4-methoxyphenyl)amino]ethyl}-3-(4-meth...)
Affinity DataKi:  3.40nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Gnf

LigandPNGBDBM19552((2S)-N-{2-[(4-methoxyphenyl)amino]ethyl}-2-[(3-met...)
Affinity DataKi:  3.70nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19575((2S)-3-cyclohexyl-N-{2-[(4-methoxyphenyl)amino]eth...)
Affinity DataKi:  4nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Gnf

LigandPNGBDBM19549((2S)-3-cyclohexyl-N-{2-[(4-methoxyphenyl)amino]eth...)
Affinity DataKi:  4.60nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19568((2S)-3-cyclohexyl-N-{2-[(4-methoxyphenyl)amino]eth...)
Affinity DataKi:  5nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Gnf

LigandPNGBDBM19555((2S)-3-(2-chlorophenyl)-N-{2-[(4-methoxyphenyl)ami...)
Affinity DataKi:  5nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19649((2R)-2-(cyclohexylmethyl)-N-[(2S)-4-methanesulfony...)
Affinity DataKi:  5nM ΔG°:  -49.3kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19581((2S)-2-{[5-(4-chlorophenyl)furan-2-yl]formamido}-3...)
Affinity DataKi:  7.10nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Gnf

LigandPNGBDBM19565((2S)-3-(1H-indol-2-yl)-N-{2-[(4-methoxyphenyl)amin...)
Affinity DataKi:  7.20nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Gnf

LigandPNGBDBM19545((2S)-N-{2-[(4-methoxyphenyl)amino]ethyl}-4-methyl-...)
Affinity DataKi:  7.20nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
UniversitÀ

LigandPNGBDBM82141(WIN 55212-2)
Affinity DataKi:  7.30nM ΔG°:  -46.4kJ/molepH: 7.4 T: 2°CAssay Description:CB1 competitive assay were performed in rat cerebellar membranes using [3H]WIN 55212-2 from Perkin-Elmer as a radioligand.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19572((2S)-2-{[4-(3-chlorophenyl)phenyl]formamido}-3-cyc...)
Affinity DataKi:  7.40nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19573((2S)-3-cyclohexyl-N-{2-[(4-methoxyphenyl)amino]eth...)
Affinity DataKi:  8nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
UniversitÀ

LigandPNGBDBM82135(5-Substituted derivative, 5)
Affinity DataKi:  8.40nM ΔG°:  -46.1kJ/molepH: 7.4 T: 2°CAssay Description:CB1 competitive assay were performed in rat cerebellar membranes using [3H]WIN 55212-2 from Perkin-Elmer as a radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19571((2S)-3-cyclohexyl-N-{2-[(4-methoxyphenyl)amino]eth...)
Affinity DataKi:  9.10nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Gnf

LigandPNGBDBM19558((2S)-3-(4-methoxyphenyl)-N-{2-[(4-methoxyphenyl)am...)
Affinity DataKi:  9.30nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19569((2S)-2-[(5-chloro-1-benzofuran-2-yl)formamido]-3-c...)
Affinity DataKi:  9.40nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19549((2S)-3-cyclohexyl-N-{2-[(4-methoxyphenyl)amino]eth...)
Affinity DataKi:  9.70nM ΔG°:  -47.6kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19655((2R)-2-(2-cyclopentylethyl)-N-[(2S)-3-methyl-1-{[4...)
Affinity DataKi:  11nM ΔG°:  -47.3kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19646((2R)-2-(cyclohexylmethyl)-N-[(2S)-3-methyl-1-{[4-(...)
Affinity DataKi:  11nM ΔG°:  -47.3kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19653((2R)-2-(cyclopentylmethyl)-4-(morpholin-4-yl)-4-ox...)
Affinity DataKi:  12nM ΔG°:  -47.0kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19645((2R)-2-(cyclohexylmethyl)-4-(morpholin-4-yl)-4-oxo...)
Affinity DataKi:  13nM ΔG°:  -46.8kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Gnf

LigandPNGBDBM19568((2S)-3-cyclohexyl-N-{2-[(4-methoxyphenyl)amino]eth...)
Affinity DataKi:  13nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19662((2R)-N-[(2S)-3-methyl-1-{[4-(trifluoromethoxy)phen...)
Affinity DataKi:  14nM ΔG°:  -46.6kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Gnf

LigandPNGBDBM19570((2S)-3-cyclohexyl-N-{2-[(4-methoxyphenyl)amino]eth...)
Affinity DataKi:  14nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
UniversitÀ

LigandPNGBDBM82140(4-methyl-N-({1-[2-(morpholin-4-yl)ethyl]-1H-indol-...)
Affinity DataKi:  15.7nM ΔG°:  -44.5kJ/molepH: 7.4 T: 2°CAssay Description:CB1 competitive assay were performed in rat cerebellar membranes using [3H]WIN 55212-2 from Perkin-Elmer as a radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19553((2S)-3-(4-chlorophenyl)-N-{2-[(4-methoxyphenyl)ami...)
Affinity DataKi:  16nM ΔG°:  -46.3kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19644((2R)-2-(cyclohexylmethyl)-4-(morpholin-4-yl)-4-oxo...)
Affinity DataKi:  16nM ΔG°:  -46.3kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19564((2S)-N-{2-[(4-methoxyphenyl)amino]ethyl}-2-[(3-met...)
Affinity DataKi:  16nM ΔG°:  -46.3kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19574((2S)-3-cyclohexyl-N-{2-[(4-methoxyphenyl)amino]eth...)
Affinity DataKi:  17nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19647((2R)-2-(cyclohexylmethyl)-4-(morpholin-4-yl)-4-oxo...)
Affinity DataKi:  18nM ΔG°:  -46.0kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19557((2S)-N-{2-[(4-methoxyphenyl)amino]ethyl}-2-[(3-met...)
Affinity DataKi:  19nM ΔG°:  -45.8kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19656((2R)-2-(2-cyclopentylethyl)-4-(morpholin-4-yl)-4-o...)
Affinity DataKi:  20nM ΔG°:  -45.7kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19667((2S)-2-(4-chlorophenyl)-N-[(2S)-3-methyl-1-{[4-(tr...)
Affinity DataKi:  21nM ΔG°:  -45.6kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Gnf

LigandPNGBDBM19548((2S)-2-cyclohexyl-N-{2-[(4-methoxyphenyl)amino]eth...)
Affinity DataKi:  22nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Gnf

LigandPNGBDBM19559((2S)-3-(4-acetamidophenyl)-N-{2-[(4-methoxyphenyl)...)
Affinity DataKi:  23nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19548((2S)-2-cyclohexyl-N-{2-[(4-methoxyphenyl)amino]eth...)
Affinity DataKi:  23nM ΔG°:  -45.4kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19666((2S)-2-(4-fluorophenyl)-N-[(2S)-3-methyl-1-{[4-(tr...)
Affinity DataKi:  24nM ΔG°:  -45.2kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
UniversitÀ

LigandPNGBDBM82139(4-chloro-N-({1-[2-(morpholin-4-yl)ethyl]-1H-indol-...)
Affinity DataKi:  24.1nM ΔG°:  -43.5kJ/molepH: 7.4 T: 2°CAssay Description:CB1 competitive assay were performed in rat cerebellar membranes using [3H]WIN 55212-2 from Perkin-Elmer as a radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19665((2S)-N-[(2S)-3-methyl-1-{[4-(trifluoromethoxy)phen...)
Affinity DataKi:  25nM ΔG°:  -45.1kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Gnf

LigandPNGBDBM19567((2S)-N-{2-[(4-methoxyphenyl)amino]ethyl}-2-[(3-met...)
Affinity DataKi:  25nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19576((2S)-3-cyclohexyl-N-{2-[(4-methoxyphenyl)amino]eth...)
Affinity DataKi:  26nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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