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Found 187 with Last Name = 'ryu' and Initial = 'se'
TargetCarboxypeptidase A1(Bos taurus (bovine))
Pohang University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50121272((2S)-2-[(aminosulfonyl)amino]-3-phenylpropanoic ac...)
Affinity DataKi:  650nMAssay Description:Inhibitory activity of the compound against Carboxypeptidase AMore data for this Ligand-Target Pair
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50253594(1-(3,4-dihydroxyphenyl)-2-[2-(4-methoxyphenyl)-2H-...)
Affinity DataKi:  2.04E+4nMAssay Description:Binding affinity to Cdc25A (336-523) (unknown origin) expressed in Escherichia coli by steady-state kinetic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50253593(2-(3,4-Dimethylphenylamino)-5-(3-furan-2-ylallylid...)
Affinity DataKi:  2.14E+4nMAssay Description:Binding affinity to Cdc25A (336-523) (unknown origin) expressed in Escherichia coli by steady-state kinetic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50237948((E)-2-(2-(5-(4-chlorophenyl)furan-2-yl)vinyl)-6-me...)
Affinity DataKi:  2.92E+4nMAssay Description:Binding affinity to Cdc25A (336-523) (unknown origin) expressed in Escherichia coli by steady-state kinetic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase A1(Bos taurus (bovine))
Pohang University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50121270((2S)-2-({[(phenylmethyl)amino]sulfonyl}amino)-3-ph...)
Affinity DataKi:  3.50E+4nMAssay Description:Inhibitory activity of the compound against Carboxypeptidase AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50253622(2-[4-(4-chlorophenyl)-5-p-tolyl-4H-[1,2,4]triazol-...)
Affinity DataKi:  3.75E+4nMAssay Description:Binding affinity to Cdc25A (336-523) (unknown origin) expressed in Escherichia coli by steady-state kinetic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase A1(Bos taurus (bovine))
Pohang University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50121276((2S)-2-({[(2-phenylethyl)amino]sulfonyl}amino)-3-p...)
Affinity DataKi:  1.80E+5nMAssay Description:Inhibitory activity of the compound against Carboxypeptidase AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase A1(Bos taurus (bovine))
Pohang University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50121275((2S)-2-{[(methylamino)sulfonyl]amino}-3-phenylprop...)
Affinity DataKi:  1.80E+5nMAssay Description:Inhibitory activity of the compound against Carboxypeptidase AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase A1(Bos taurus (bovine))
Pohang University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50121269((2R)-2-[(aminosulfonyl)amino]-3-phenylpropanoic ac...)
Affinity DataKi:  4.70E+5nMAssay Description:Inhibitory activity of the compound against Carboxypeptidase AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase A1(Bos taurus (bovine))
Pohang University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50121273((2S)-2-{[(isopropylamino)sulfonyl]amino}-3-phenylp...)
Affinity DataKi:  6.10E+5nMAssay Description:Inhibitory activity of the compound against Carboxypeptidase AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase A1(Bos taurus (bovine))
Pohang University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50121274((2R)-2-benzyl-3-{[(methyl-lambda~5~-azanyl)sulfony...)
Affinity DataKi:  1.40E+6nMAssay Description:Inhibitory activity of the compound against Carboxypeptidase AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase A1(Bos taurus (bovine))
Pohang University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50121277(2-benzyl-3-{[(methyl-lambda~5~-azanyl)sulfonyl]ami...)
Affinity DataKi:  2.90E+6nMAssay Description:Inhibitory activity of the compound against Carboxypeptidase AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase A1(Bos taurus (bovine))
Pohang University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50121271((2S)-2-[(aminosulfonyl)(methyl)amino]-3-phenylprop...)
Affinity DataKi:  3.50E+6nMAssay Description:Inhibitory activity of the compound against Carboxypeptidase AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine-phosphatase(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50391713(CHEMBL2146956)
Affinity DataIC50:  100nMAssay Description:Inhibition of His-tagged PTPsigma catalytic domain amino acid 1369 to 1948 using DiFMUP as substrate after 20 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine-phosphatase(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50237957(4-(2-((2,5-dioxoimidazolidin-4-ylidene)methyl)-1H-...)
Affinity DataIC50:  200nMAssay Description:Inhibition of His-tagged PTPsigma catalytic domain amino acid 1369 to 1948 using DiFMUP as substrate after 20 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50456401(IRIGENOL)
Affinity DataIC50:  500nMAssay Description:Inhibition of recombinant human PTP-sigma (residues 1367 to 1948) using para-nitrophenylphosphate as substrate for 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein-tyrosine-phosphatase(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50391714(CHEMBL2146957)
Affinity DataIC50:  600nMAssay Description:Inhibition of His-tagged PTPsigma catalytic domain amino acid 1369 to 1948 using DiFMUP as substrate after 20 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM23411(5,6,7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-...)
Affinity DataIC50:  600nMAssay Description:Inhibition of recombinant human PTP-sigma (residues 1367 to 1948) using para-nitrophenylphosphate as substrate for 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine-phosphatase(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50391715(CHEMBL2146960)
Affinity DataIC50:  700nMAssay Description:Inhibition of His-tagged PTPsigma catalytic domain amino acid 1369 to 1948 using DiFMUP as substrate after 20 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50499947(CHEMBL3739950)
Affinity DataIC50:  800nMAssay Description:Inhibition of recombinant human PTP-sigma (residues 1367 to 1948) using para-nitrophenylphosphate as substrate for 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50253622(2-[4-(4-chlorophenyl)-5-p-tolyl-4H-[1,2,4]triazol-...)
Affinity DataIC50:  820nMAssay Description:Inhibition of Cdc25A (336-523) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine-phosphatase(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50391711(CHEMBL2146958)
Affinity DataIC50:  900nMAssay Description:Inhibition of His-tagged PTPsigma catalytic domain amino acid 1369 to 1948 using DiFMUP as substrate after 20 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50499946(CHEMBL3740878)
Affinity DataIC50:  900nMAssay Description:Inhibition of recombinant human PTP-sigma (residues 1367 to 1948) using para-nitrophenylphosphate as substrate for 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50184297(5-(5-(benzo[b]thiophen-3-yl)-2-(benzyloxy)benzylid...)
Affinity DataIC50:  900nMAssay Description:Inhibition of human recombinant PRL-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50184288(5-(2-(2-bromobenzyloxy)-5-bromobenzylidene)-2-thio...)
Affinity DataIC50:  900nMAssay Description:Inhibition of human recombinant PRL-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50296442(5-(2-methyl-3-phenylallylidene)-2-(phenylamino)thi...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of N-terminal 6xHis-tagged (378-566) catalytic domain of Cdc25B expressed in Escherichia coli after 20 mins by by fluorescent plate reader...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine-phosphatase(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50387974(CHEMBL2057830)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of His-tagged PTPsigma catalytic domain amino acid 1369 to 1948 using DiFMUP as substrate after 20 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50184287(5-(5-(benzofuran-3-yl)-2-(benzyloxy)benzylidene)-2...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human recombinant PRL-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine-phosphatase(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50391712(CHEMBL2146959)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of His-tagged PTPsigma catalytic domain amino acid 1369 to 1948 using DiFMUP as substrate after 20 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50296467(2-(5-(4-chlorophenyl)-4-phenyl-4H-1,2,4-triazol-3-...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of N-terminal 6xHis-tagged (378-566) catalytic domain of Cdc25B expressed in Escherichia coli after 20 mins by by fluorescent plate reader...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50184285(5-(2-(4-bromobenzyloxy)benzylidene)-2-thioxothiazo...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human recombinant PRL-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology (Kribb)

Curated by ChEMBL
LigandPNGBDBM50179012(CHEMBL382338 | Sanggenon G)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50184296(5-((3-(2-chloro-6-fluorobenzyloxy)naphthalen-2-yl)...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human recombinant PRL-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50184298(5-(4-Benzyloxy-biphenyl-3-ylmethylene)-2-thioxo-th...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human recombinant PRL-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50296456(1-(3,4-dihydroxyphenyl)-2-(5-(4-methoxyphenyl)-4-p...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of N-terminal 6xHis-tagged (378-566) catalytic domain of Cdc25B expressed in Escherichia coli after 20 mins by by fluorescent plate reader...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50253593(2-(3,4-Dimethylphenylamino)-5-(3-furan-2-ylallylid...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of N-terminal 6xHis-tagged (378-566) catalytic domain of Cdc25B expressed in Escherichia coli after 20 mins by by fluorescent plate reader...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50184293(5-[1-[3-(biphenyl-4-ylmethoxy)-naphthalen-2-yl]-me...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human recombinant PRL-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50253622(2-[4-(4-chlorophenyl)-5-p-tolyl-4H-[1,2,4]triazol-...)
Affinity DataIC50:  1.98E+3nMAssay Description:Inhibition of Cdc25B (378-566) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50184291(5-((3-(benzyloxy)naphthalen-2-yl)methylene)-2-thio...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human recombinant PRL-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50296462(1-(biphenyl-4-yl)-2-(5-(furan-2-yl)-4-methyl-4H-1,...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of N-terminal 6xHis-tagged (378-566) catalytic domain of Cdc25B expressed in Escherichia coli after 20 mins by by fluorescent plate reader...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50296443(2-(2-chlorophenylamino)-5-(3-(furan-2-yl)allyliden...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of N-terminal 6xHis-tagged (378-566) catalytic domain of Cdc25B expressed in Escherichia coli after 20 mins by by fluorescent plate reader...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50296444(2-(2,3-dichlorophenylamino)-5-(3-(furan-2-yl)allyl...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of N-terminal 6xHis-tagged (378-566) catalytic domain of Cdc25B expressed in Escherichia coli after 20 mins by by fluorescent plate reader...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 4(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50391713(CHEMBL2146956)
Affinity DataIC50:  2.29E+3nMAssay Description:Inhibition of MKP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50296466(1-(3,4-dihydroxyphenyl)-2-(4-(furan-2-yl)-5-p-toly...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of N-terminal 6xHis-tagged (378-566) catalytic domain of Cdc25B expressed in Escherichia coli after 20 mins by by fluorescent plate reader...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50296447(2-(3,4-dimethylphenylamino)-5-(2-methyl-3-phenylal...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of N-terminal 6xHis-tagged (378-566) catalytic domain of Cdc25B expressed in Escherichia coli after 20 mins by by fluorescent plate reader...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50296450(2-(3,5-dichlorophenylamino)-5-(3-(furan-2-yl)allyl...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of N-terminal 6xHis-tagged (378-566) catalytic domain of Cdc25B expressed in Escherichia coli after 20 mins by by fluorescent plate reader...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50296453(5-((1H-indol-3-yl)methylene)-2-(3,5-dichlorophenyl...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of N-terminal 6xHis-tagged (378-566) catalytic domain of Cdc25B expressed in Escherichia coli after 20 mins by by fluorescent plate reader...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50184290(5-(2-(2-chlorobenzyloxy)-5-bromobenzylidene)-2-thi...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of human recombinant PRL-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50296465(1-(3,4-dihydroxyphenyl)-2-(4-phenyl-5-p-tolyl-4H-1...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of N-terminal 6xHis-tagged (378-566) catalytic domain of Cdc25B expressed in Escherichia coli after 20 mins by by fluorescent plate reader...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology (Kribb)

Curated by ChEMBL
LigandPNGBDBM50179008(CHEMBL204813 | sanggenon C)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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