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Found 50 with Last Name = 'saberi' and Initial = 'mr'
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10007(4-[(6-methoxy-1-benzofuran-2-yl)(1H-1,2,4-triazol-...)
Affinity DataIC50:  10nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10013(4-[(6-Hydroxybenzofuran-2-yl)-[1,2,4]triazol-1-ylm...)
Affinity DataIC50:  20nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10000((4-fluorophenyl)(6-methoxy-1-benzofuran-2-yl)pyrid...)
Affinity DataIC50:  44nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10005(1-[(4-chlorophenyl)(6-methoxy-1-benzofuran-2-yl)me...)
Affinity DataIC50:  44nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10001((4-chlorophenyl)(6-methoxy-1-benzofuran-2-yl)pyrid...)
Affinity DataIC50:  49nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10004(1-[(4-fluorophenyl)(6-methoxy-1-benzofuran-2-yl)me...)
Affinity DataIC50:  49nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10014(2-[(4-Nitrophenyl)-[1,2,4]triazol-1-ylmethyl]benzo...)
Affinity DataIC50:  60nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10009(1-[(6-Methoxybenzofuran-2-yl)-p-tolylmethyl]-1H-1,...)
Affinity DataIC50:  100nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10003(1-[(6-Methoxybenzofuran-2-yl)-(4-methoxyphenyl)met...)
Affinity DataIC50:  130nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10006(1-[(6-Methoxybenzofuran-2-yl)-(4-methoxyphenyl)met...)
Affinity DataIC50:  130nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10010(1-[(6-Methoxybenzofuran-2-yl)-(4-trifluoromethylph...)
Affinity DataIC50:  130nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10002((6-Methoxybenzofuran-2-yl)-(4-methoxyphenyl)-3-pyr...)
Affinity DataIC50:  160nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308952(4-Methyl-6-({3-[(4-methylpiperidino)carbonyl]-benz...)
Affinity DataIC50:  430nMAssay Description:Inhibition of human PDE3A by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10015(2-[3-(1-cyano-1-methylethyl)-5-(1H-1,2,4-triazol-1...)
Affinity DataIC50:  600nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10015(2-[3-(1-cyano-1-methylethyl)-5-(1H-1,2,4-triazol-1...)
Affinity DataIC50:  600nMT: 2°CAssay Description:The classical 3H2O assay was used to measure the effect of the inhibitor compounds on aromatase activity using human placental microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10008(1-[(6-Methoxybenzofuran-2-yl)-(4-nitrophenyl)methy...)
Affinity DataIC50:  600nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308954(4-Methyl-6-{[3-(tetrahydro-1H-1-pyrrolylcarbonyl)-...)
Affinity DataIC50:  640nMAssay Description:Inhibition of human PDE3A by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308951(4-Methyl-6-{[3-(piperidinocarbonyl)benzyl]oxy}-1,2...)
Affinity DataIC50:  660nMAssay Description:Inhibition of human PDE3A by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308949(1-(3-{[(4-Methyl-2-oxo-1,2-dihydro-6-quinolinyl)ox...)
Affinity DataIC50:  840nMAssay Description:Inhibition of human PDE3A by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308950(6-({3-[(4-Hydroxypiperidino)carbonyl]benzyl}oxy)-4...)
Affinity DataIC50:  910nMAssay Description:Inhibition of human PDE3B by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308948(4-Methyl-6-(3-[(4-oxopiperidino)carbonyl]benzyloxy...)
Affinity DataIC50:  1.14E+3nMAssay Description:Inhibition of human PDE3B by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308954(4-Methyl-6-{[3-(tetrahydro-1H-1-pyrrolylcarbonyl)-...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human PDE3B by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10011(1-[(4-ethylphenyl)(6-methoxy-1-benzofuran-2-yl)met...)
Affinity DataIC50:  1.23E+3nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308948(4-Methyl-6-(3-[(4-oxopiperidino)carbonyl]benzyloxy...)
Affinity DataIC50:  1.26E+3nMAssay Description:Inhibition of human PDE3A by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308949(1-(3-{[(4-Methyl-2-oxo-1,2-dihydro-6-quinolinyl)ox...)
Affinity DataIC50:  1.28E+3nMAssay Description:Inhibition of human PDE3B by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM86018(Pyridylmethanol, 8f)
Affinity DataIC50:  1.30E+3nMT: 2°CAssay Description:The classical 3H2O assay was used to measure the effect of the inhibitor compounds on aromatase activity using human placental microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308953(4-Methyl-6-{[3-(morpholinocarbonyl)benzyl]oxy}-1,2...)
Affinity DataIC50:  1.34E+3nMAssay Description:Inhibition of human PDE3A by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308950(6-({3-[(4-Hydroxypiperidino)carbonyl]benzyl}oxy)-4...)
Affinity DataIC50:  1.35E+3nMAssay Description:Inhibition of human PDE3A by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308946(4-Methyl-6-({3-[(4-ethylpiperazino)carbonyl]-benzy...)
Affinity DataIC50:  1.44E+3nMAssay Description:Inhibition of human PDE3A by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10012(2-[(4-Chlorophenyl)-[1,2,4]triazol-1-ylmethyl]benz...)
Affinity DataIC50:  1.46E+3nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308953(4-Methyl-6-{[3-(morpholinocarbonyl)benzyl]oxy}-1,2...)
Affinity DataIC50:  1.54E+3nMAssay Description:Inhibition of human PDE3B by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308952(4-Methyl-6-({3-[(4-methylpiperidino)carbonyl]-benz...)
Affinity DataIC50:  1.61E+3nMAssay Description:Inhibition of human PDE3B by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308947(6-[(3-{[4-(2-Hydroxyethyl)piperazino]carbonyl}-ben...)
Affinity DataIC50:  1.65E+3nMAssay Description:Inhibition of human PDE3A by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308951(4-Methyl-6-{[3-(piperidinocarbonyl)benzyl]oxy}-1,2...)
Affinity DataIC50:  1.73E+3nMAssay Description:Inhibition of human PDE3B by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308945(4-Methyl-6-({3-[(4-methylpiperazino)carbonyl]-benz...)
Affinity DataIC50:  1.76E+3nMAssay Description:Inhibition of human PDE3A by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308946(4-Methyl-6-({3-[(4-ethylpiperazino)carbonyl]-benzy...)
Affinity DataIC50:  1.93E+3nMAssay Description:Inhibition of human PDE3B by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM86017(Pyridylmethanol, 8e)
Affinity DataIC50:  2.20E+3nMT: 2°CAssay Description:The classical 3H2O assay was used to measure the effect of the inhibitor compounds on aromatase activity using human placental microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308947(6-[(3-{[4-(2-Hydroxyethyl)piperazino]carbonyl}-ben...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of human PDE3B by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308956(6-(3-(4-methylpiperazine-1-carbonyl)benzyloxy)quin...)
Affinity DataIC50:  2.84E+3nMAssay Description:Inhibition of human PDE3A by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308945(4-Methyl-6-({3-[(4-methylpiperazino)carbonyl]-benz...)
Affinity DataIC50:  3.51E+3nMAssay Description:Inhibition of human PDE3B by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM86014(Pyridylmethanol, 8b)
Affinity DataIC50:  4.30E+3nMT: 2°CAssay Description:The classical 3H2O assay was used to measure the effect of the inhibitor compounds on aromatase activity using human placental microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308956(6-(3-(4-methylpiperazine-1-carbonyl)benzyloxy)quin...)
Affinity DataIC50:  5.67E+3nMAssay Description:Inhibition of human PDE3B by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM86013(Pyridylmethanol, 8a)
Affinity DataIC50:  7.00E+3nMT: 2°CAssay Description:The classical 3H2O assay was used to measure the effect of the inhibitor compounds on aromatase activity using human placental microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50016980(6-(4-(3,4-dimethoxybenzoyl)piperazin-1-yl)-3,4-dih...)
Affinity DataIC50:  1.07E+4nMAssay Description:Inhibition of human PDE3A by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM86016(Pyridylmethanol, 8d)
Affinity DataIC50:  1.28E+4nMT: 2°CAssay Description:The classical 3H2O assay was used to measure the effect of the inhibitor compounds on aromatase activity using human placental microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50016980(6-(4-(3,4-dimethoxybenzoyl)piperazin-1-yl)-3,4-dih...)
Affinity DataIC50:  1.32E+4nMAssay Description:Inhibition of human PDE3B by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)
Affinity DataIC50:  1.85E+4nMT: 2°CAssay Description:The classical 3H2O assay was used to measure the effect of the inhibitor compounds on aromatase activity using human placental microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM86015(Pyridylmethanol, 8c)
Affinity DataIC50:  2.51E+4nMT: 2°CAssay Description:The classical 3H2O assay was used to measure the effect of the inhibitor compounds on aromatase activity using human placental microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM86020(Pyridylmethanol, 9b)
Affinity DataIC50: >1.00E+5nMT: 2°CAssay Description:The classical 3H2O assay was used to measure the effect of the inhibitor compounds on aromatase activity using human placental microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM86019(Pyridylmethanol, 9a)
Affinity DataIC50: >1.00E+5nMT: 2°CAssay Description:The classical 3H2O assay was used to measure the effect of the inhibitor compounds on aromatase activity using human placental microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed