Compile Data Set for Download or QSAR
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Found 6 with Last Name = 'schaffer' and Initial = 'sa'
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022279(3-(2,4-Difluoro-phenyl)-1-[4-(2,2-dimethyl-propyl)...)
Affinity DataIC50:  140nMAssay Description:Inhibition of smooth muscle cell ACAT activity for cells stimulated by cationized LDL.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022279(3-(2,4-Difluoro-phenyl)-1-[4-(2,2-dimethyl-propyl)...)
Affinity DataIC50:  740nMAssay Description:Compound was evaluated for the effect on Cholesterol O-Acyltransferase (ACAT) in Liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022279(3-(2,4-Difluoro-phenyl)-1-[4-(2,2-dimethyl-propyl)...)
Affinity DataIC50:  810nMAssay Description:Compound was evaluated for the effect on Cholesterol O-Acyltransferase (ACAT) in intestinal microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022279(3-(2,4-Difluoro-phenyl)-1-[4-(2,2-dimethyl-propyl)...)
Affinity DataIC50:  1.09E+3nMAssay Description:Compound was evaluated for the effect on Cholesterol O-Acyltransferase (ACAT) in Aorta (homogenate Low-density lipoproteins (LDL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022279(3-(2,4-Difluoro-phenyl)-1-[4-(2,2-dimethyl-propyl)...)
Affinity DataIC50:  6.06E+3nMAssay Description:Inhibition of smooth muscle cell ACAT activity for cells stimulated by native LDL.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM8903((1S,2R,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltet...)
Affinity DataIC50:  1.70E+4nMAssay Description:In vitro inhibitory activity against acyl coenzyme A:cholesterol acyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed